Reactome | monoSUMO1-K263-NPM1 [nucleoplasm]

monoSUMO1-K263-NPM1 [nucleoplasm]

Stable Identifier

R-HSA-4086039

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Nucleophosmin, NPM_HUMAN

Locations in the PathwayBrowser for interactor UniProt:O00566 MPHOSPH10

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External Reference Information

External Reference

UniProt:P06748 NPM1

Gene Names

NPM1, NPM

Chain

chain:1-294

Reference Genes

BioGPS Gene:4869 NPM1

COSMIC (genes):NPM1 NPM1

CTD Gene:4869 NPM1

dbSNP Gene:4869 NPM1

ENSEMBL:ENSG00000181163 NPM1

ENSEMBL_homo_sapiens_GENE:ENSG00000181163.14 NPM1

HGNC:7910 NPM1

KEGG Gene (Homo sapiens):4869 NPM1

Monarch:4869 NPM1

NCBI Gene:4869 NPM1

OMIM:164040 NPM1

UCSC:P06748 NPM1

Reference Transcript

Other Identifiers

11730790_x_at

11730912_at

11754066_x_at

11757362_x_at

11757386_x_at

16656591

16656593

16656595

18670158

18670159

18670165

18670166

18670167

200063_PM_s_at

200063_s_at

221691_3p_x_at

221691_PM_x_at

221691_x_at

221923_PM_s_at

221923_s_at

2326906

2666248

2840617

2840618

2840620

2840621

2840623

2840626

2840627

2840628

2840629

2840631

2840633

2840638

2840640

2840641

2840642

2840643

2840646

2840647

2840648

2867271

2867272

2867273

2867274

2867275

2867281

2867283

2960052

2960054

3100478

3100479

3136166

3404467

3404471

38542_at

4869

78344_at

7892530

7892853

7893382

7893420

7893571

7893657

7894485

7894919

7895119

7895225

7895472

7895509

7896054

8109975

8180407

8180408

8180409

88066_s_at

A_14_P116462

A_14_P127485

A_23_P214037

A_24_P188941

GE79895

GO:0000055

GO:0000056

GO:0001046

GO:0001558

GO:0001652

GO:0003676

GO:0003677

GO:0003682

GO:0003713

GO:0003723

GO:0004860

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005813

GO:0005815

GO:0005829

GO:0005840

GO:0005856

GO:0005925

GO:0006281

GO:0006325

GO:0006334

GO:0006338

GO:0006351

GO:0006355

GO:0006407

GO:0006884

GO:0006886

GO:0006913

GO:0007010

GO:0007098

GO:0007165

GO:0008104

GO:0008284

GO:0008285

GO:0010608

GO:0010629

GO:0010824

GO:0010825

GO:0010826

GO:0012501

GO:0015934

GO:0015935

GO:0016020

GO:0016071

GO:0016607

GO:0019843

GO:0019901

GO:0023052

GO:0030957

GO:0031328

GO:0031398

GO:0031616

GO:0031647

GO:0032071

GO:0032991

GO:0032993

GO:0034644

GO:0036211

GO:0042254

GO:0042255

GO:0042273

GO:0042274

GO:0042393

GO:0042802

GO:0042803

GO:0043023

GO:0043024

GO:0043066

GO:0043226

GO:0043516

GO:0044387

GO:0045727

GO:0045893

GO:0045944

GO:0046599

GO:0048025

GO:0050821

GO:0051059

GO:0051082

GO:0051092

GO:0051726

GO:0060090

GO:0060699

GO:0060735

GO:0065003

GO:0090398

GO:0098772

GO:0140110

GO:0140297

GO:0140693

GO:1902629

GO:1902751

GO:1904751

GO:1990904

HMNXSV003029586

HMNXSV003034873

HMNXSV003056309

Hs.9614.1.A1_3p_a_at

ILMN_1678775

M23613_at

PH_hs_0030093

TC01000357.hg

TC05000942.hg

g12803184_3p_a_at

g13536990_3p_s_at

Participates

as an output of

SUMOylation of NPM1 with SUMO1 (Homo sapiens)

Other forms of this molecule

polySUMO2,3-K263-NPM1 [nucleoplasm]

NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm]

NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol]

NPM1(1-117)-ALK(1068-1620) fusion [cytosol]

NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol]

NPM1(1-117)-ALK(1058-1620) fusion [cytosol]

NPM1 [granular component]

NPM1 [nucleoplasm]

NPM1 [cytosol]

p-S4-NPM1 [cytosol]

Inferred To

LOC511386 [nucleoplasm] (Bos taurus)

NPM1 [nucleoplasm] (Bos taurus)

NPM1 [nucleoplasm] (Sus scrofa)

monoSUMO1-K263-NPM1 [nucleoplasm] (Bos taurus)

monoSUMO1-K263-NPM1 [nucleoplasm] (Gallus gallus)

npm1 [nucleoplasm] (Xenopus tropicalis)

Homologues of monoSUMO1-K263-NPM1 [nucleoplasm] (Bos taurus)

Npm1 [nucleoplasm] (Mus musculus)

Npm1 [nucleoplasm] (Rattus norvegicus)

Modified Residues

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 263

Coordinate

263

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

NP_001032827.1, NP_002511.1, NP_954654.1

OpenTargets

ENSG00000181163

GeneCards

P06748

HPA

ENSG00000181163-NPM1

Ensembl

ENSG00000181163, ENSP00000341168, ENSP00000296930, ENST00000678280, ENST00000517671, ENST00000393820, ENST00000351986, ENSP00000377408, ENST00000296930, ENSP00000428755, ENSP00000503235

PRO

P06748

Pharos - Targets

P06748

Orphanet

17401

PDB

8AS5, 2P1B, 5EHD, 8AH2, 7OBG, 7OBH, 2VXD, 2LLH

Interactors (143)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H4L4 SENP3	1	SENP3 [nucleoplasm] (R-HSA-2984296)	0.78	7
UniProt:Q96BK5 PINX1			0.757	12
UniProt:Q86SE8 NPM2	1	NPM2 [nucleoplasm] (R-HSA-9821980)	0.743	8
UniProt:O75607 NPM3			0.725	6
UniProt:Q9BQG0 MYBBP1A	1	MYBBP1A [nucleoplasm] (R-HSA-5250650)	0.712	4
UniProt:Q00987 MDM2	11	PolyUb-MDM2 [nucleoplasm] (R-HSA-6782472) monoSUMO1-K182-MDM2 [nucleoplasm] (R-HSA-3000408) p-S166,S188,T218-MDM2 [nucleoplasm] (R-HSA-6792862) p-5S,T-MDM2 [nucleoplasm] (R-HSA-6804954) PolyUb,p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6795669) MDM2 [plasma membrane] (R-HSA-416843) MDM2 [endocytic vesicle membrane] (R-HSA-416849) MDM2 [nucleoplasm] (R-HSA-69486) MDM2 [cytosol] (R-HSA-198644) p-S166,S188-MDM2 [cytosol] (R-HSA-198638) p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6793669)	0.697	5
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.676	6
UniProt:Q71RC2 LARP4			0.669	3
UniProt:Q8IZL8 PELP1	1	PELP1 [nucleoplasm] (R-HSA-3826531)	0.664	4
UniProt:P62753 RPS6	4	RPS6 [nucleoplasm] (R-HSA-6790606) 3OHR147-RPS6 [cytosol] (R-HSA-9629876) p-5S-RPS6 [cytosol] (R-HSA-165727) RPS6 [cytosol] (R-HSA-72381)	0.65	3
UniProt:Q96CT7 CC124			0.649	8
UniProt:Q9BZE4 GTPB4			0.643	4
UniProt:Q13823 NOG2			0.643	3
UniProt:P61313 RPL15	1	RPL15 [cytosol] (R-HSA-72416)	0.643	3
UniProt:Q14690 PDCD11	1	PDCD11 [nucleoplasm] (R-HSA-6790646)	0.643	3
UniProt:Q14684 RRP1B			0.643	4
UniProt:Q15397 PUM3			0.643	4
UniProt:P46777 RPL5	1	RPL5 [cytosol] (R-HSA-72482)	0.643	3
UniProt:P46781 RPS9	2	RPS9 [nucleoplasm] (R-HSA-6790663) RPS9 [cytosol] (R-HSA-72387)	0.643	3
UniProt:Q14137 BOP1	1	BOP1 [nucleoplasm] (R-HSA-6791206)	0.643	3
UniProt:B1Q2W9 B1Q2W9			0.639	8
UniProt:Q96GD4 AURKB	3	polySUMO2,3-K202-AURKB [cytosol] (R-HSA-4655414) AURKB [nucleoplasm] (R-HSA-4655360) AURKB [cytosol] (R-HSA-174231)	0.626	5
UniProt:P24938 CORE5			0.623	4
UniProt:Q6UPD4 Q6UPD4			0.619	4
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	15
UniProt:P19338 NCL	3	NCL [plasma membrane] (R-HSA-9836466) NCL [macropinosome membrane] (R-HSA-9837666) NCL [nucleoplasm] (R-HSA-6791213)	0.615	3
UniProt:Q9BZQ8 NIBA1			0.602	7
UniProt:P19525 EIF2AK2	5	p-EIF2AK2 [nucleoplasm] (R-HSA-9836332) SUMO-EIF2AK2 [cytosol] (R-HSA-9834829) ISG15-EIF2AK2 [cytosol] (R-HSA-9833968) p-EIF2AK2 [cytosol] (R-HSA-9833834) EIF2AK2 [cytosol] (R-HSA-168699)	0.602	4
UniProt:Q9BXL5 HEMGN			0.599	7
UniProt:P49450 CENPA	2	CENPA [nucleoplasm] (R-HSA-606322) CENPA [cytosol] (R-HSA-375317)	0.597	4
UniProt:P68951 NP			0.591	5
UniProt:P05549 TFAP2A	1	TFAP2A [nucleoplasm] (R-HSA-8864280)	0.591	6
UniProt:O00505 KPNA3	2	KPNA3 [nucleoplasm] (R-HSA-1176061) KPNA3 [cytosol] (R-HSA-1176070)	0.59	2
UniProt:O14746 TERT	1	TERT [nucleoplasm] (R-HSA-163076)	0.576	5
UniProt:P0DOE7 M	5	p-S95,T205-M [cytosol] (R-RSY-9831678) p-S95,T205-M [nucleoplasm] (R-RSY-9831706) M [nucleoplasm] (R-RSY-9831711) Nascent M [cytosol] (R-RSY-9828672) p-S95,T205-M [viral tegument] (R-RSY-9836531)	0.576	3
UniProt:P49207 RPL34	1	RPL34 [cytosol] (R-HSA-72458)	0.564	2
UniProt:Q9NX58 LYAR			0.564	2
UniProt:P63104 YWHAZ	2	YWHAZ [nucleoplasm] (R-HSA-450469) YWHAZ [cytosol] (R-HSA-206099)	0.564	2
UniProt:Q96MT8 CEP63	1	CEP63 [cytosol] (R-HSA-380267)	0.564	2
UniProt:Q8N726 CDKN2A	12	p14ARF [nucleoplasm] (R-HSA-1629813) p14ARF [cytosol] (R-HSA-9645669) p14ARF [mitochondrial matrix] (R-HSA-9645695) p14ARF R98L;R99S [cytosol] (R-HSA-9645730) p14ARF R82C [cytosol] (R-HSA-9645750) p14ARF R90H [cytosol] (R-HSA-9645755) p14ARF R88Q [cytosol] (R-HSA-9645754) p14ARF R87C [cytosol] (R-HSA-9645759) p14ARF R81G [cytosol] (R-HSA-9645741) p14ARF R98Q [cytosol] (R-HSA-9645757) p14ARF R99C [cytosol] (R-HSA-9645756) p14ARF V22Pfs*46 [cytosol] (R-HSA-9646285)	0.564	2
UniProt:Q92876 KLK6			0.556	3
UniProt:Q86SE8-2 NPM2			0.556	5
UniProt:P10176 COX8A	1	COX8A [mitochondrial inner membrane] (R-HSA-164313)	0.556	3
UniProt:P60228 EIF3E	1	EIF3E [cytosol] (R-HSA-72552)	0.547	2
UniProt:P03427 PB2			0.547	3
UniProt:P03372 ESR1	8	p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) Me260-ESR1 [cytosol] (R-HSA-9632177) PalmS-ESR1 [cytosol] (R-HSA-9020974) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.532	3
UniProt:O76021 RL1D1			0.527	2
UniProt:Q92522 H1X			0.527	2
UniProt:P62424 RPL7A	1	RPL7A [cytosol] (R-HSA-72488)	0.527	2
UniProt:Q6PGP7 SKIC3	1	TTC37 [cytosol] (R-HSA-8931541)	0.527	2
UniProt:Q9Y3C1 NOP16			0.527	3
UniProt:P22087 FBL	1	FBL [nucleoplasm] (R-HSA-6790638)	0.527	2
UniProt:Q07020 RPL18	1	RPL18 [cytosol] (R-HSA-72420)	0.527	2
UniProt:Q9HCM4 EPB41L5	1	EPB41L5 [cytosol] (R-HSA-6797564)	0.527	2
UniProt:Q99848 EBNA1BP2	1	EBNA1BP2 [nucleoplasm] (R-HSA-8869325)	0.527	3
UniProt:P39019 RPS19	2	RPS19 [nucleoplasm] (R-HSA-6798710) RPS19 [cytosol] (R-HSA-72343)	0.527	2
UniProt:Q15050 RRS1			0.527	3
UniProt:O00566 MPHOSPH10	1	MPHOSPH10 [nucleoplasm] (R-HSA-6790661)	0.527	2
UniProt:P63220 RPS21	2	RPS21 [nucleoplasm] (R-HSA-6798732) RPS21 [cytosol] (R-HSA-72351)	0.527	2
UniProt:O00567 NOP56	2	NOP56 [nucleoplasm] (R-HSA-6790696) NOP56 [cytosol] (R-HSA-391293)	0.527	2
UniProt:Q1ED39 KNOP1			0.527	2
UniProt:O15381 NVL			0.527	2
UniProt:P10636-8 MAPT	3	p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) MAPT-8 [cytosol] (R-HSA-9619519)	0.527	6
UniProt:Q96PV0 SYNGAP1	1	SYNGAP1 [cytosol] (R-HSA-5658217)	0.527	2
UniProt:Q7Z478 DHX29			0.527	2
UniProt:Q14692 BMS1	1	BMS1 [nucleoplasm] (R-HSA-6790720)	0.527	2
UniProt:Q9ULW3 ABT1			0.527	2
UniProt:P35268 RPL22	1	RPL22 [cytosol] (R-HSA-72428)	0.527	2
UniProt:Q06787 FMR1			0.527	3
UniProt:Q12788 TBL3	1	TBL3 [nucleoplasm] (R-HSA-6790620)	0.527	2
UniProt:P60866 RPS20	2	RPS20 [nucleoplasm] (R-HSA-6798727) RPS20 [cytosol] (R-HSA-72349)	0.527	2
UniProt:Q5JTH9 RRP12			0.527	2
UniProt:Q9Y3B9 RRP15			0.527	2
UniProt:O75683 SURF6			0.527	3
UniProt:P62750 RPL23A	1	RPL23A [cytosol] (R-HSA-72432)	0.527	3
UniProt:Q6P158 DHX57			0.527	2
UniProt:O76094 SRP72	1	SRP72 [cytosol] (R-HSA-265069)	0.527	2
UniProt:P05386 RPLP1	1	RPLP1 [cytosol] (R-HSA-72398)	0.527	2
UniProt:Q6PK04 CC137			0.527	2
UniProt:Q8TDN6 BRX1			0.527	3
UniProt:Q9NW13 RBM28	1	RBM28 [nucleoplasm] (R-HSA-6791192)	0.527	2
UniProt:Q96GQ7 DDX27			0.527	3
UniProt:Q9NRX1 PNO1	2	PNO1 [nucleoplasm] (R-HSA-6791540) PNO1 [cytosol] (R-HSA-6791509)	0.527	2
UniProt:Q49A26 GLYR1			0.527	3
UniProt:P49711 CTCF	1	CTCF [nucleoplasm] (R-HSA-3782562)	0.527	2
UniProt:Q14694 USP10	3	USP10 [nucleoplasm] (R-HSA-3222218) K63polyUb-USP10 [cytosol] (R-HSA-6782986) USP10 [cytosol] (R-HSA-6782974)	0.527	2
UniProt:Q9GZL7 WDR12	1	WDR12 [nucleoplasm] (R-HSA-6791215)	0.527	2
UniProt:P62861 FAU	2	FAU [nucleoplasm] (R-HSA-6798717) FAU [cytosol] (R-HSA-72371)	0.527	2
UniProt:Q969S3 ZN622			0.527	2
UniProt:P36578 RPL4	1	RPL4 [cytosol] (R-HSA-72474)	0.527	3
UniProt:Q14152 EIF3A	1	EIF3A [cytosol] (R-HSA-72546)	0.527	2
UniProt:P42696 RBM34			0.527	3
UniProt:P50914 RPL14	1	RPL14 [cytosol] (R-HSA-72414)	0.527	2
UniProt:Q9GZR2 REXO4			0.527	3
UniProt:P46013 KI67			0.527	2
UniProt:O75818 RPP40	1	RPP40 [nucleoplasm] (R-HSA-5696801)	0.527	3
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:O95707 POP4	1	POP4 [nucleoplasm] (R-HSA-5696789)	0.527	3
UniProt:O15226 NKRF			0.527	2
UniProt:P15880 RPS2	3	RPS2 [nucleoplasm] (R-HSA-6790655) Me2aR-RPS2 [cytosol] (R-HSA-8879138) RPS2 [cytosol] (R-HSA-72347)	0.527	2
UniProt:Q15477 SKIC2	1	SKIV2L [cytosol] (R-HSA-391294)	0.527	2
UniProt:Q9UNX4 WDR3	1	WDR3 [nucleoplasm] (R-HSA-6790724)	0.527	2
UniProt:P62906 RPL10A	1	RPL10A [cytosol] (R-HSA-72404)	0.527	2
UniProt:P35251 RFC1	1	RFC1 [nucleoplasm] (R-HSA-68435)	0.527	2
UniProt:Q96HI0 SENP5	1	SENP5 [nucleoplasm] (R-HSA-2984297)	0.527	3
UniProt:Q8TDD1 DDX54			0.527	3
UniProt:P46783 RPS10	2	RPS10 [nucleoplasm] (R-HSA-6798733) RPS10 [cytosol] (R-HSA-72325)	0.527	2
UniProt:P46782 RPS5	2	RPS5 [nucleoplasm] (R-HSA-6791188) RPS5 [cytosol] (R-HSA-72379)	0.527	2
UniProt:Q9P287 BCCIP			0.527	2
UniProt:P62857 RPS28	2	RPS28 [nucleoplasm] (R-HSA-6791202) RPS28 [cytosol] (R-HSA-72365)	0.527	2
UniProt:O60264 SMARCA5	1	SMARCA5 [nucleoplasm] (R-HSA-417140)	0.527	2
UniProt:Q9BYG3 MK67I			0.527	2
UniProt:Q9H7B2 RPF2			0.527	2
UniProt:P61513 RPL37A	1	RPL37A [cytosol] (R-HSA-72468)	0.527	2
UniProt:Q99613 EIF3C	1	EIF3C [cytosol] (R-HSA-72550)	0.527	2
UniProt:Q13283 G3BP1	1	G3BP1 [cytosol] (R-HSA-9729517)	0.527	2
UniProt:P62280 RPS11	2	RPS11 [nucleoplasm] (R-HSA-6791212) RPS11 [cytosol] (R-HSA-72327)	0.527	2
UniProt:Q99575 POP1	1	POP1 [nucleoplasm] (R-HSA-5696802)	0.527	2
UniProt:Q9BQ39 DDX50			0.527	2
UniProt:Q9NXF1 TEX10	1	TEX10 [nucleoplasm] (R-HSA-3826589)	0.527	3
UniProt:P78346 RPP30	1	RPP30 [nucleoplasm] (R-HSA-5696779)	0.527	2
UniProt:Q7KZF4 SND1	2	SND1(1-593)-BRAF(381-766) fusion [cytosol] (R-HSA-6802469) SND1(1-593)-p-BRAF(381-766) fusion [cytosol] (R-HSA-6802552)	0.527	2
UniProt:Q9Y4W2 LAS1L	1	LAS1L [nucleoplasm] (R-HSA-6791521)	0.527	2
UniProt:Q6NW34 NEPRO			0.527	3
UniProt:Q9H6F5 CCD86			0.527	2
UniProt:Q6DKI1 RL7L			0.527	3
UniProt:P62263 RPS14	2	RPS14 [nucleoplasm] (R-HSA-6790669) RPS14 [cytosol] (R-HSA-72333)	0.527	2
UniProt:Q01780 EXOSC10	1	EXOSC10 [nucleoplasm] (R-HSA-6791547)	0.527	2
UniProt:O43159 RRP8	1	RRP8 [nucleoplasm] (R-HSA-427524)	0.527	3
UniProt:O96028 NSD2	2	p-S102-WHSC1 [nucleoplasm] (R-HSA-5682984) WHSC1 [nucleoplasm] (R-HSA-1183215)	0.527	2
UniProt:Q71UM5 RPS27L	2	RPS27L [nucleoplasm] (R-HSA-6791197) RPS27L [cytosol] (R-HSA-8868849)	0.527	2
UniProt:P62241 RPS8	2	RPS8 [nucleoplasm] (R-HSA-6791203) RPS8 [cytosol] (R-HSA-72385)	0.527	2
UniProt:Q8IY81 FTSJ3	1	FTSJ3 [nucleoplasm] (R-HSA-6791507)	0.527	3
UniProt:P40429 RPL13A	2	p-RPL13A [cytosol] (R-HSA-156829) RPL13A [cytosol] (R-HSA-72412)	0.527	2
UniProt:Q6PKG0 LARP1	1	LARP1 [cytosol] (R-HSA-9760421)	0.527	2
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.524	2
UniProt:Q98147 Q98147			0.524	2
UniProt:Q14684-1 RRP1B			0.512	4
UniProt:Q10570 CPSF1	1	CPSF1 [nucleoplasm] (R-HSA-71989)	0.499	2
UniProt:Q9UQ80 PA2G4	2	PA2G4 [extracellular region] (R-HSA-6806200) PA2G4 [azurophil granule lumen] (R-HSA-6799205)	0.491	3
UniProt:O14965 AURKA	6	SUMO1-K258-AURKA [cytosol] (R-HSA-4655367) p-T288-AURKA [nucleoplasm] (R-HSA-6805089) AURKA [nucleoplasm] (R-HSA-4655443) PolyUb-AURKA [cytosol] (R-HSA-8854040) AURKA [cytosol] (R-HSA-174254) p-T288-AURKA [cytosol] (R-HSA-2574832)	0.489	3
UniProt:Q8IUH3 RBM45			0.462	2
UniProt:P11387 TOP1	2	monoSUMO1-K117-TOP1 [nucleoplasm] (R-HSA-4641364) TOP1 [nucleoplasm] (R-HSA-4641363)	0.462	3

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