monoSUMO1-5K-ESR1 [nucleoplasm]

Stable Identifier
R-HSA-4090302
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Estrogen receptor, ESR1_HUMAN
monoSUMO1-5K-ESR1 [nucleoplasm] icon
Locations in the PathwayBrowser for interactor UniProt:P42229 STAT5A
External Reference Information
External Reference
Gene Names
ESR1, ESR, NR3A1
Chain
chain:1-595
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 266
Coordinate
266
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 268
Coordinate
268
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 299
Coordinate
299
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 302
Coordinate
302
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 303
Coordinate
303
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Interactors (271)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P03372 ESR1  10 0.87 11
 UniProt:P12931 SRC  6 0.848 12
 UniProt:Q15788 NCOA1  3 0.835 8
 UniProt:Q04206 RELA  7 0.832 9
 UniProt:P38398 BRCA1  20 0.811 16
 IntAct:EBI-5590876 TFF1      0.788 6
 UniProt:P06401 PGR  3 0.774 20
 UniProt:P55345 ANM2      0.75 9
 UniProt:Q6PL18 ATAD2  1 0.737 5
 UniProt:Q9H1R3 MYLK2      0.725 5
 UniProt:P60709 ACTB  5 0.723 6
 UniProt:P62701 RPS4X  2 0.69 4
 UniProt:P05388 RPLP0  1 0.69 4
 UniProt:P62854 RPS26  2 0.69 5
 UniProt:Q969Q0 RPL36AL  1 0.69 5
 UniProt:Q9BQ69 MACD1      0.69 6
 UniProt:Q9Y6Q9 NCOA3  2 0.688 4
 UniProt:P29279 CTGF  1 0.682 7
 UniProt:P19838-PRO_0000030311 NFKB1      0.676 3
 UniProt:Q02447 SP3  3 0.667 4
 UniProt:Q6NYC1 JMJD6  1 0.649 8
 UniProt:Q9Y294 ASF1A  1 0.647 4
 UniProt:P06576 ATP5F1B  6 0.643 4
 UniProt:P17844 DDX5  4 0.643 4
 UniProt:P60660 MYL6  2 0.642 3
 UniProt:O15164 TRIM24  4 0.641 3
 UniProt:P60763 RAC3  3 0.639 5
 UniProt:Q8N895 ZN366      0.633 6
 UniProt:O43524 FOXO3  11 0.632 7
 UniProt:Q03989 ARI5A      0.625 9
 UniProt:P53041 PPP5C  2 0.625 4
 UniProt:P23771 GATA3  2 0.623 4
 UniProt:P05627 Jun  5 0.616 6
 UniProt:Q9Y3R0 GRIP1  2 0.609 2
 UniProt:P62263 RPS14  2 0.597 3
 UniProt:P35579 MYH9  3 0.597 3
 UniProt:Q5JTH9 RRP12      0.597 4
 UniProt:P10276 RARA  3 0.597 4
 UniProt:Q00610 CLTC  10 0.597 3
 UniProt:P11142 HSPA8  10 0.597 3
 UniProt:P61513 RPL37A  1 0.597 4
 UniProt:P27635 RPL10  1 0.597 4
 UniProt:P06396 GSN  7 0.597 3
 UniProt:Q8IZL8 PELP1  1 0.597 3
 UniProt:Q13547 HDAC1  2 0.597 4
 UniProt:Q96GQ7 DDX27      0.597 4
 UniProt:Q9BVP2 GNL3  1 0.597 4
 UniProt:O43823 AKAP8      0.597 4
 UniProt:Q92841 DDX17  2 0.597 3
 UniProt:P21333 FLNA  3 0.597 3
 UniProt:Q01130 SRSF2  1 0.597 4
 UniProt:P06401-1 PGR      0.593 4
 UniProt:Q12802 AKAP13  1 0.593 3
 UniProt:Q9Y6C7 L3R2A      0.593 3
 UniProt:O60869 EDF1      0.59 3
 UniProt:P17676 CEBPB  3 0.59 2
 UniProt:P18846 ATF1  2 0.59 3
 UniProt:Q15596 NCOA2  3 0.584 5
 UniProt:O43251 RBFOX2  1 0.581 4
 UniProt:Q96AQ6-1 PBXIP1      0.576 3
 IntAct:EBI-10099285 VITA2      0.576 5
 UniProt:Q86Y37 CACL1      0.571 5
 UniProt:P36873 PPP1CC  1 0.564 3
 UniProt:P48552 NRIP1  2 0.564 3
 UniProt:Q15648 MED1  1 0.564 3
 UniProt:Q9UHF7 TRPS1      0.564 4
 UniProt:P00523 SRC  9 0.564 2
 UniProt:P08047 SP1  1 0.558 2
 UniProt:O76024 WFS1  3 0.556 3
 UniProt:Q6ZQX7-4 Q6ZQX74      0.556 3
 UniProt:Q16881-4 TXNRD1      0.556 4
 UniProt:P62962 Pfn1  2 0.556 3
 UniProt:Q6XD76 ASCL4      0.556 3
 UniProt:Q9UBK2 PPARGC1A  4 0.553 2
 UniProt:Q9BZ95 NSD3  1 0.547 3
 IntAct:EBI-2695616 ERE      0.544 2
 UniProt:Q96Q04 LMTK3      0.544 3
 UniProt:Q14151 SAFB2      0.544 2
 UniProt:Q09472 EP300  5 0.536 2
 UniProt:Q92731 ESR2  5 0.532 3
 UniProt:P06748 NPM1  11 0.532 3
 UniProt:P82673 MRPS35  1 0.527 3
 UniProt:P62269 RPS18  2 0.527 2
 UniProt:Q99832 CCT7  1 0.527 2
 UniProt:P68363 TUBA1B  9 0.527 3
 UniProt:P05109 S100A8  3 0.527 2
 UniProt:Q96SB4 SRPK1  2 0.527 3
 UniProt:Q9HCM4 EPB41L5  1 0.527 3
 UniProt:Q9NX58 LYAR      0.527 3
 UniProt:Q8NI36 WDR36  1 0.527 3
 UniProt:O00165 HAX1      0.527 2
 IntAct:EBI-1265559 MYC      0.527 3
 UniProt:Q13823 NOG2      0.527 3
 UniProt:P08865 RPSA  2 0.527 3
 UniProt:Q9NSY1 BMP2K      0.527 3
 UniProt:Q9UPN3 MACF1      0.527 3
 UniProt:Q14684 RRP1B      0.527 3
 UniProt:P60866 RPS20  2 0.527 2
 UniProt:Q9NPD3 EXOSC4  2 0.527 3
 UniProt:Q7Z406 MYH14  1 0.527 2
 UniProt:O95793 STAU1      0.527 2
 UniProt:Q9BY89 K1671      0.527 3
 UniProt:Q5M775 CYTSB      0.527 3
 UniProt:P27708 CAD  1 0.527 3
 UniProt:Q9Y399 MRPS2  2 0.527 3
 UniProt:Q15084 PDIA6  3 0.527 3
 UniProt:P07205 PGK2  1 0.527 2
 UniProt:Q9BUF5 TUBB6  6 0.527 3
 UniProt:Q9NPJ6 MED4  1 0.527 3
 UniProt:P56192 MARS1  1 0.527 3
 UniProt:Q04637 EIF4G1  2 0.527 3
 UniProt:P42224 STAT1  8 0.527 3
 UniProt:O75146 HIP1R  3 0.527 3
 UniProt:Q96L91 EP400  1 0.527 3
 UniProt:P46940 IQGAP1  3 0.527 3
 UniProt:O60784 TOM1  3 0.527 3
 UniProt:O75110 ATP9A  1 0.527 3
 UniProt:P28290 ITPI2      0.527 3
 UniProt:P82650 MRPS22  1 0.527 3
 UniProt:P12268 IMPDH2  4 0.527 3
 UniProt:Q92665 MRPS31  1 0.527 3
 UniProt:O43432 EIF4G3  1 0.527 3
 UniProt:Q96EY7 PTCD3  1 0.527 3
 UniProt:Q8IYT4 KATL2      0.527 2
 UniProt:P53680 AP2S1  4 0.527 3
 UniProt:Q9UBF2 COPG2  4 0.527 3
 UniProt:P62158 CALM      0.527 3
 UniProt:Q92552 MRPS27  1 0.527 3
 UniProt:P62952 BLCAP      0.527 2
 UniProt:O60568 PLOD3  1 0.527 2
 UniProt:P12814 ACTN1  3 0.527 3
 UniProt:Q9Y4P3 TBL2      0.527 3
 UniProt:Q9NQZ2 UTP3  1 0.527 3
 UniProt:P32455 GBP1  1 0.527 2
 UniProt:Q9BRD0 BUD13  1 0.527 3
 UniProt:Q9UN36 NDRG2      0.527 2
 UniProt:Q7Z2W4 ZC3HAV1  2 0.527 3
 UniProt:O43175 PHGDH  1 0.527 3
 UniProt:Q15291 RBBP5  1 0.527 4
 UniProt:P05089 ARG1  4 0.527 2
 UniProt:Q8WUY1 THEM6      0.527 3
 UniProt:Q9Y2R5 MRPS17  1 0.527 2
 UniProt:Q6NYC8 PPR18      0.527 3
 UniProt:Q8NHW5 RLA0L      0.527 2
 UniProt:Q9BVJ6 UTP14A  1 0.527 3
 UniProt:Q9UBL3 ASH2L  1 0.527 4
 UniProt:Q9H3U1 UN45A      0.527 3
 UniProt:P62191 PSMC1  2 0.527 3
 UniProt:P60842 EIF4A1  1 0.527 3
 UniProt:Q96KN2 CNDP1      0.527 2
 UniProt:Q9Y4I1 MYO5A  2 0.527 3
 UniProt:P25398 RPS12  2 0.527 2
 UniProt:Q9UM54 MYO6  3 0.527 2
 UniProt:Q15233 NONO      0.527 3
 UniProt:P78362 SRPK2  1 0.527 3
 UniProt:Q96HI0 SENP5  1 0.527 2
 UniProt:Q9BUP0 EFHD1      0.527 2
 UniProt:Q16576 RBBP7  1 0.527 3
 UniProt:Q7L2E3 DHX30      0.527 3
 UniProt:Q99575 POP1  1 0.527 3
 UniProt:Q9BQ39 DDX50      0.527 3
 UniProt:Q9Y3U8 RPL36  1 0.527 3
 UniProt:Q8N201 INTS1  1 0.527 3
 UniProt:Q8IXJ9 ASXL1  1 0.527 2
 UniProt:Q9Y230 RUVBL2  1 0.527 2
 UniProt:Q92754 TFAP2C  3 0.527 3
 UniProt:O00429 DNM1L  2 0.527 2
 UniProt:P62244 RPS15A  2 0.527 3
 UniProt:P50454 SERPINH1  1 0.527 3
 UniProt:O14686 KMT2D  1 0.525 3
 UniProt:P42229 STAT5A  4 0.524 2
 UniProt:Q9H467 CUED2      0.524 2
 UniProt:Q9BTK6 PAGR1  1 0.524 5
 UniProt:Q99966 CITED1  1 0.524 3
 UniProt:Q9JLI4 NCOA6      0.508 2
 UniProt:Q99623 PHB2  1 0.508 4
 UniProt:P59598  1 0.508 2
 UniProt:Q12778 FOXO1  5 0.508 2
 UniProt:P20290-2 BTF3      0.508 5
 UniProt:Q00987 MDM2  11 0.508 2
 UniProt:Q60974 Ncor1  3 0.508 2
 UniProt:Q9NV06 DCAF13  1 0.499 2
 UniProt:O95835 LATS1  2 0.499 2
 UniProt:PGR ENSG00000082175      0.499 3
 UniProt:Q9NPJ4 PNRC2  1 0.488 2
 UniProt:P27986 PIK3R1  16 0.483 7
 UniProt:Q925T6  2 0.482 2
 UniProt:P83881 RPL36A  1 0.462 2
 UniProt:O76021 RL1D1      0.462 2
 UniProt:hCG_2020860 A0A024RC46      0.462 2
 UniProt:P38159 RBMX  2 0.462 2
 UniProt:Q9NYF8 BCLF1      0.462 2
 UniProt:Q07020 RPL18  1 0.462 2
 UniProt:Q92769 HDAC2  2 0.462 2
 UniProt:Q01844 EWS      0.462 2
 UniProt:P39023 RPL3  1 0.462 2
 UniProt:O00159 MYO1C  1 0.462 2
 UniProt:Q08211 DHX9  3 0.462 2
 UniProt:Q16629 SRSF7  1 0.462 2
 UniProt:Q14444 CAPR1      0.462 2
 UniProt:P17480 UBTF  2 0.462 2
 UniProt:Q6PJG2 MDEAS      0.462 2
 UniProt:P05141 SLC25A5  1 0.462 2
 UniProt:Q9NVP1 DDX18      0.462 2
 UniProt:P02787 TF  6 0.462 2
 UniProt:P02786 TFRC  5 0.462 2
 UniProt:P62917 RPL8  3 0.462 2
 UniProt:P04843 RPN1  1 0.462 2
 UniProt:P04844 RPN2  1 0.462 2
 UniProt:P36578 RPL4  1 0.462 2
 UniProt:P46013 KI67      0.462 2
 UniProt:Q14669 TRIP12  1 0.462 2
 UniProt:Q9P035 HACD3  1 0.462 2
 UniProt:P11387 TOP1  2 0.462 2
 UniProt:P83731 RPL24  1 0.462 2
 UniProt:P68032 ACTC1  1 0.462 2
 UniProt:P09651 HNRNPA1  2 0.462 2
 UniProt:Q02543 RPL18A  1 0.462 2
 UniProt:P19338 NCL  3 0.462 2
 UniProt:O43795 MYO1B      0.462 2
 UniProt:Q12905 ILF2  5 0.462 2
 UniProt:P18124 RPL7  1 0.462 2
 UniProt:O00571 DDX3X  3 0.462 2
 UniProt:P62424 RPL7A  1 0.462 2
 UniProt:Q32P51 RA1L2      0.462 2
 UniProt:Q14980 NUMA1  3 0.462 2
 UniProt:Q9BZE4 GTPB4      0.462 2
 UniProt:O00567 NOP56  2 0.462 2
 UniProt:Q9NVI7 ATD3A      0.462 2
 UniProt:P61313 RPL15  1 0.462 2
 UniProt:P35268 RPL22  1 0.462 2
 UniProt:P14923 JUP  6 0.462 2
 UniProt:Q96HS1 PGAM5      0.462 2
 UniProt:P52272 HNRNPM  1 0.462 2
 UniProt:Q02878 RPL6  1 0.462 2
 UniProt:P62753 RPS6  4 0.462 2
 UniProt:Q8IY81 FTSJ3  1 0.462 2
 UniProt:P51991 HNRNPA3  1 0.462 2
 UniProt:P50914 RPL14  1 0.462 2
 UniProt:P18621 RPL17  1 0.462 2
 UniProt:P26373 RPL13  1 0.462 2
 UniProt:P84098 RPL19  1 0.462 2
 UniProt:O43390 HNRNPR  1 0.462 2
 UniProt:P61247 RPS3A  2 0.462 2
 UniProt:Q8TDD1 DDX54      0.462 2
 UniProt:O43143 DHX15  1 0.462 2
 UniProt:Q9H0A0 NAT10  1 0.462 2
 UniProt:P35637 FUS  1 0.462 2
 UniProt:Q9NR30 DDX21  1 0.462 2
 UniProt:Q14498 RBM39  1 0.462 2
 UniProt:P40429 RPL13A  2 0.462 2
 UniProt:P62249 RPS16  2 0.462 2
 UniProt:Q8IYB3 SRRM1  2 0.462 2
 UniProt:P26368 U2AF2  2 0.462 2
 UniProt:O60832 DKC1  1 0.462 2
 UniProt:Q96PK6 RBM14  1 0.462 2
 UniProt:P11388 TOP2A  3 0.462 2
 UniProt:P46776 RPL27A  3 0.462 2
 UniProt:P0CG47 UBB  20 0.462 2
 UniProt:Q9BQG0 MYBBP1A  1 0.462 2
 UniProt:P62266 RPS23  3 0.462 2
 UniProt:P62241 RPS8  2 0.462 2
 UniProt:P11940 PABPC1  1 0.462 2
 UniProt:Q07955 SRSF1  1 0.462 2
 UniProt:P15880 RPS2  3 0.462 2
 UniProt:Q02880 TOP2B  2 0.462 2
 UniProt:P09874 PARP1  4 0.462 2
 UniProt:P61978 HNRNPK  2 0.462 2
 UniProt:P52597 HNRNPF  2 0.462 2
 UniProt:P46781 RPS9  2 0.462 2
 UniProt:Q9Y2W1 THRAP3  1 0.462 2
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