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NHP2 [nucleoplasm]
Stable Identifier
R-HSA-418325
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
H/ACA ribonucleoprotein complex subunit 2, NHP2_HUMAN
Locations in the PathwayBrowser for interactor UniProt:O60832 DKC1
Expand all
Cell Cycle (Homo sapiens)
Chromosome Maintenance (Homo sapiens)
Telomere Maintenance (Homo sapiens)
Extension of Telomeres (Homo sapiens)
Telomere Extension By Telomerase (Homo sapiens)
Biogenesis and assembly of the telomerase RNP (Homo sapiens)
NHP2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NX24 NHP2
Gene Names
NHP2, NOLA2, HSPC286
Chain
chain:1-153
Reference Genes
BioGPS Gene:55651 NHP2
COSMIC (genes):NHP2 NHP2
CTD Gene:55651 NHP2
dbSNP Gene:55651 NHP2
ENSEMBL:ENSG00000145912 NHP2
ENSEMBL_homo_sapiens_GENE:ENSG00000145912.10 NHP2
HGNC:14377 NHP2
KEGG Gene (Homo sapiens):55651 NHP2
Monarch:55651 NHP2
NCBI Gene:55651 NHP2
OMIM:606470 NHP2
UCSC:Q9NX24 NHP2
Reference Transcript
RefSeq:NM_001034833.1 NHP2
RefSeq:NM_017838.3 NHP2
Other Identifiers
11718338_a_at
11757725_a_at
11757726_x_at
17003479
209104_PM_s_at
209104_s_at
2889457
2889458
2889460
2889461
2889463
2889464
2994023
3258088
3258089
3258090
3258091
41322_s_at
55651
7929243
8116168
A_24_P63608
A_33_P3389942
GE55516
GO:0000470
GO:0000781
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005697
GO:0005730
GO:0005732
GO:0005829
GO:0005840
GO:0006364
GO:0007004
GO:0015030
GO:0016073
GO:0022625
GO:0031118
GO:0031120
GO:0031429
GO:0032200
GO:0034513
GO:0042254
GO:0043226
GO:0070034
GO:0072589
GO:0090661
GO:1904874
GO:1990904
HMNXSV003058429
Hs.302184.0.S1_3p_s_at
ILMN_1718672
ILMN_2365544
PH_hs_0024392
g12652540_3p_s_at
Participates
as a component of
Box H/ACA snoRNP [nucleoplasm] (Homo sapiens)
Telomerase RNP [nucleoplasm] (Homo sapiens)
as an input of
Biogenesis and assembly of the telomerase RNP (Homo sapiens)
Inferred To
NHP2 [nucleoplasm]
(Bos taurus)
NHP2 [nucleoplasm]
(Caenorhabditis elegans)
NHP2 [nucleoplasm]
(Canis familiaris)
NHP2 [nucleoplasm]
(Drosophila melanogaster)
NHP2 [nucleoplasm]
(Gallus gallus)
NHP2 [nucleoplasm]
(Rattus norvegicus)
NHP2 [nucleoplasm]
(Saccharomyces cerevisiae)
NHP2 [nucleoplasm]
(Sus scrofa)
Nhp2 [nucleoplasm]
(Mus musculus)
nola2 [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of NHP2 [nucleoplasm]
(Plasmodium falciparum)
nhp2 [nucleoplasm]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_060308.1
,
NP_001030005.1
OpenTargets
ENSG00000145912
GeneCards
Q9NX24
HPA
ENSG00000145912-NHP2
Ensembl
ENSG00000145912
,
ENSP00000274606
,
ENST00000274606
PRO
Q9NX24
Pharos - Targets
Q9NX24
Orphanet
18490
PDB
8OUE
,
7TRC
,
7V9A
,
7BGB
,
8OUF
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NPE3 NOP10
1
NOP10 [nucleoplasm]
(R-HSA-6790665)
0.919
12
UniProt:O60832 DKC1
1
DKC1 [nucleoplasm]
(R-HSA-163102)
0.731
4
UniProt:Q9NX58 LYAR
0.564
2
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
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