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Reduction of cytosolic Ca++ levels
Stable Identifier
R-HSA-418359
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
Locations in the PathwayBrowser
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Hemostasis (Homo sapiens)
Platelet homeostasis (Homo sapiens)
Platelet calcium homeostasis (Homo sapiens)
Reduction of cytosolic Ca++ levels (Homo sapiens)
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During steady state conditions, cytoplasmic [Ca2+] is reduced by the accumulation of Ca2+ in intracellular stores and Ca2+ extrusion.
Literature References
PubMed ID
Title
Journal
Year
18308196
Intracellular calcium release from human platelets: different messengers for multiple stores
Jardin, I
,
López, JJ
,
Rosado, JA
,
Salido, GM
,
Pariente, JA
Trends Cardiovasc Med
2008
Participants
Events
ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen
(Homo sapiens)
ATP2B1-4 transport cytosolic Ca2+ to extracellular region
(Homo sapiens)
SLC8A1,2,3 exchange 3Na+ for Ca2+
(Homo sapiens)
Participates
as an event of
Platelet calcium homeostasis (Homo sapiens)
Orthologous Events
Reduction of cytosolic Ca++ levels (Bos taurus)
Reduction of cytosolic Ca++ levels (Caenorhabditis elegans)
Reduction of cytosolic Ca++ levels (Canis familiaris)
Reduction of cytosolic Ca++ levels (Danio rerio)
Reduction of cytosolic Ca++ levels (Dictyostelium discoideum)
Reduction of cytosolic Ca++ levels (Drosophila melanogaster)
Reduction of cytosolic Ca++ levels (Gallus gallus)
Reduction of cytosolic Ca++ levels (Mus musculus)
Reduction of cytosolic Ca++ levels (Plasmodium falciparum)
Reduction of cytosolic Ca++ levels (Rattus norvegicus)
Reduction of cytosolic Ca++ levels (Saccharomyces cerevisiae)
Reduction of cytosolic Ca++ levels (Schizosaccharomyces pombe)
Reduction of cytosolic Ca++ levels (Sus scrofa)
Reduction of cytosolic Ca++ levels (Xenopus tropicalis)
Cross References
BioModels Database
BIOMD0000000467
,
BIOMD0000000468
,
BIOMD0000000088
Authored
Akkerman, JW (2009-06-03)
Reviewed
Kunapuli, SP (2010-06-07)
Created
Jupe, S (2009-04-21)
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