Reactome | PRKG2 [cytosol]

PRKG2 [cytosol]

Stable Identifier

R-HSA-418377

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

cGMP-dependent protein kinase 2, KGP2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q13237 PRKG2

Gene Names

PRKG2, PRKGR2

Chain

initiator methionine:, chain:2-762

Reference Genes

BioGPS Gene:5593 PRKG2

COSMIC (genes):PRKG2 PRKG2

CTD Gene:5593 PRKG2

dbSNP Gene:5593 PRKG2

ENSEMBL:ENSG00000138669 PRKG2

HGNC:9416 PRKG2

KEGG:hsa:5593 PRKG2

Monarch:5593 PRKG2

NCBI Gene:5593 PRKG2

OMIM:601591 PRKG2

UCSC:Q13237 PRKG2

Reference Transcript

Other Identifiers

11740761_at

11746813_a_at

16977286

207505_PM_at

207505_at

2775210

2775211

2775213

2775215

2775216

2775217

2775218

2775219

2775221

2775223

2775224

2775225

2775226

2775227

2775229

2775230

2775231

2775232

2775233

2775238

2775239

2775240

2775241

2775244

2775245

2775246

33536_at

5593

8101284

A_23_P69663

A_33_P3342598

GE60165

GO:0003824

GO:0004672

GO:0004674

GO:0004692

GO:0005524

GO:0005829

GO:0005886

GO:0006468

GO:0007165

GO:0010737

GO:0016324

GO:0016740

GO:0030553

GO:0031965

GO:0032332

GO:0042802

GO:0046146

GO:0051019

GO:0072659

GO:0106310

GO:0140096

GO:1903829

GO:2001226

HMNXSV003012277

ILMN_1804870

PH_hs_0003086

TC04001330.hg

X94612_at

g5453977_3p_at

Participates

as a member of

Cyclic GMP-dependent protein kinases (PKGs) [cytosol] (Homo sapiens)

as a component of

PRKG2 dimer [cytosol] (Homo sapiens)

Inferred To

Dmel\CG4839 [cytosol] (Drosophila melanogaster)

Homologues of PRKG2 [cytosol] (Drosophila melanogaster)

PRKG2 [cytosol] (Bos taurus)

PRKG2 [cytosol] (Canis familiaris)

PRKG2 [cytosol] (Drosophila melanogaster)

PRKG2 [cytosol] (Gallus gallus)

PRKG2 [cytosol] (Mus musculus)

PRKG2 [cytosol] (Rattus norvegicus)

PRKG2 [cytosol] (Sus scrofa)

PRKG2 [cytosol] (Xenopus tropicalis)

Cross References

Guide to Pharmacology - Targets

1493

OpenTargets

ENSG00000138669

ENSEMBL

ENST00000628926, ENST00000395578, ENST00000264399, ENSP00000264399, ENSP00000486129, ENSG00000138669, ENSP00000378945

ZINC - FDA approved

KGP2_HUMAN

ZINC - Substances

KGP2_HUMAN

ZINC - Biogenic

KGP2_HUMAN

ZINC target

Q13237

PRO

Q13237

PDB

5BV6, 5C6C, 5JIZ, 5C8W, 5JIX, 6BQ8

ZINC - Investigational

KGP2_HUMAN

IntEnz

2.7.11.12

HPA

ENSG00000138669-PRKG2

GeneCards

PRKG2

Pharos - Targets

Q13237

ZINC - Predictions - Purchasable

KGP2_HUMAN

HMDB Protein

HMDBP01125

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13432 U119A			0.527	3