Reactome | CTNND1 [plasma membrane]

CTNND1 [plasma membrane]

Stable Identifier

R-HSA-418996

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

p120 catenin

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O60716 CTNND1

Gene Names

CTNND1, KIAA0384

Chain

chain:1-968

Reference Genes

BioGPS Gene:1500 CTNND1

COSMIC (genes):CTNND1 CTNND1

CTD Gene:1500 CTNND1

dbSNP Gene:1500 CTNND1

ENSEMBL:ENSG00000198561 CTNND1

ENSEMBL:ENSG00000198561.16 CTNND1

HGNC:2515 CTNND1

KEGG Gene (Homo sapiens):1500 CTNND1

Monarch:1500 CTNND1

NCBI Gene:1500 CTNND1

OMIM:601045 CTNND1

UCSC:O60716 CTNND1

Reference Transcript

Other Identifiers

11721647_a_at

11722067_a_at

11750587_a_at

11750588_x_at

11754087_a_at

1500

1557944_3p_s_at

1557944_PM_s_at

1557944_s_at

208407_PM_s_at

208407_s_at

208862_PM_s_at

208862_s_at

211240_PM_x_at

211240_x_at

3331526

3331527

3331528

3331529

3331542

3331544

3331545

3331546

3331551

3331554

3331555

3331557

3331561

3331562

3331564

3331565

3331567

3331568

3331570

3331572

3331573

3331577

3331578

3331579

3331581

3331583

3331584

3331585

3331586

3331587

3331588

3331589

3331590

3331591

3331592

3331593

3827571

40443_at

40444_s_at

61840_s_at

7940079

AB002382_at

A_14_P115076

A_14_P117957

A_23_P251316

A_23_P95080

A_24_P38930

A_33_P3209716

GE54575

GO:0005102

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0005829

GO:0005886

GO:0005911

GO:0005912

GO:0005915

GO:0007043

GO:0007155

GO:0008013

GO:0009986

GO:0016020

GO:0016055

GO:0016342

GO:0019901

GO:0023052

GO:0030027

GO:0030426

GO:0030496

GO:0034330

GO:0043197

GO:0043226

GO:0044331

GO:0045296

GO:0050821

GO:0050839

GO:0051220

GO:0070062

GO:0070161

GO:0090090

GO:0098609

GO:0098685

GO:0098686

GO:0098831

GO:0098978

GO:0099072

GO:0099092

GO:1990782

HMNXSV003012934

Hs.166011.3.A1_3p_a_at

Hs2.426620.1.S1_3p_s_at

ILMN_1696806

ILMN_2293511

PH_hs_0010002

TC11002681.hg

TC11003450.hg

g10835009_3p_a_at

Participates

as an output of

CBLL1 binds SRC-phosphorylated CDH1 complex (Homo sapiens)

as a component of

as an input of

Inferred To

Ctnnd1 [plasma membrane] (Mus musculus)

Ctnnd1 [plasma membrane] (Rattus norvegicus)

ctnnd1 [plasma membrane] (Xenopus tropicalis)

CTNND1 [plasma membrane] (Bos taurus)

CTNND1 [plasma membrane] (Canis familiaris)

CTNND1 [plasma membrane] (Danio rerio)

CTNND1 [plasma membrane] (Gallus gallus)

CTNND1 [plasma membrane] (Sus scrofa)

p120ctn [plasma membrane] (Drosophila melanogaster)

jac-1 [plasma membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001078928.1, NP_001078927.1, NP_001193817.1, NP_001193813.1, NP_001193812.1, NP_001078934.1, NP_001193816.1, NP_001078938.1, NP_001078930.1, NP_001078933.1, NP_001078937.1, NP_001078929.1, NP_001193815.1, NP_001322.1, NP_001078936.1, NP_001193819.1, NP_001193814.1, NP_001193820.1, NP_001078932.1, NP_001078935.1, NP_001193818.1, NP_001078931.1

OpenTargets

ENSG00000198561

GeneCards

O60716

HPA

ENSG00000198561-CTNND1

Ensembl

ENSP00000434017, ENST00000531014, ENST00000399050, ENST00000526772, ENSP00000354823, ENSP00000437327, ENSP00000354785, ENST00000361332, ENST00000526938, ENSP00000436543, ENST00000358694, ENSP00000437156, ENSP00000413586, ENSP00000432623, ENSP00000435379, ENST00000532463, ENST00000526357, ENSP00000435494, ENST00000415361, ENST00000532245, ENST00000673683, ENST00000361796, ENST00000525902, ENSP00000434672, ENSP00000432243, ENST00000530094, ENSG00000198561, ENST00000529873, ENST00000527467, ENST00000529526, ENSP00000351527, ENST00000361391, ENSP00000432041, ENST00000534579, ENST00000528232, ENSP00000435266, ENSP00000500962, ENSP00000435789, ENST00000532787, ENSP00000432075, ENSP00000354907, ENSP00000433158, ENST00000530748, ENST00000532649, ENSP00000433276, ENST00000428599, ENSP00000436744, ENST00000529986, ENSP00000382004, ENST00000533667, ENST00000532844, ENST00000528621, ENSP00000403518, ENSP00000434949, ENST00000524630, ENSP00000434900, ENST00000426142, ENSP00000433334, ENSP00000436323, ENSP00000409930, ENSP00000437051

PRO

O60716

Pharos - Targets

O60716

Orphanet

24444

PDB

3L6X, 3L6Y

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.745	5
UniProt:Q12913 PTPRJ	2	PTPRJ [specific granule membrane] (R-HSA-6799570) PTPRJ [plasma membrane] (R-HSA-6785269)	0.724	5
UniProt:O14495 PLPP3	1	PPAP2B [plasma membrane] (R-HSA-76132)	0.644	9
UniProt:Q6IQ23 PKHA7			0.636	5
UniProt:Q7Z6J6 FRMD5			0.537	3
UniProt:P12830 CDH1	8	CDH1(732-882) [plasma membrane] (R-HSA-3827997) CDH1(155-700) [plasma membrane] (R-HSA-2534244) CDH1(701-882) [extracellular region] (R-HSA-2534158) Ub-K,p-Y753,Y754-CDH1(155-882) [plasma membrane] (R-HSA-8877002) p-Y753,Y754-CDH1(155-882) [plasma membrane] (R-HSA-8876938) CDH1(155-750) [plasma membrane] (R-HSA-202940) CDH1(751-882) [plasma membrane] (R-HSA-202929) CDH1(155-882) [plasma membrane] (R-HSA-198003)	0.483	4
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	9

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