Reactome | CDH8 [plasma membrane]

CDH8 [plasma membrane]

Stable Identifier

R-HSA-419000

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Cadherin-8, CADH8_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P55286 CDH8

Gene Names

CDH8

Chain

signal peptide:1-29, propeptide:30-61, chain:62-799

Reference Genes

BioGPS Gene:1006 CDH8

COSMIC (genes):CDH8 CDH8

CTD Gene:1006 CDH8

dbSNP Gene:1006 CDH8

ENSEMBL:ENSG00000150394 CDH8

HGNC:1767 CDH8

KEGG:hsa:1006 CDH8

Monarch:1006 CDH8

NCBI Gene:1006 CDH8

OMIM:603008 CDH8

UCSC:P55286 CDH8

Reference Transcript

RefSeq:NM_001796.4 CDH8

Other Identifiers

1006

11739319_at

1484_at

16827022

210518_PM_at

210518_at

217574_PM_at

217574_at

231438_PM_x_at

231438_x_at

241500_PM_at

241500_at

3694214

3694216

3694217

3694218

3694219

3694221

3694230

3694231

3694232

3694233

3694234

3694235

3694236

3694238

3694239

3694240

3694241

3694242

3694243

3694244

3694255

3694256

3694257

3694258

3694259

3694260

3694263

3694264

3694266

3694271

3694276

3694277

3694278

3694301

3694302

3694303

37289_at

37290_at

42334_at

8001784

A_23_P140797

GE53880

GE604441

GE683032

GO:0000902

GO:0005509

GO:0005576

GO:0005886

GO:0005912

GO:0007043

GO:0007155

GO:0007156

GO:0007268

GO:0008013

GO:0009409

GO:0016020

GO:0016339

GO:0016342

GO:0016477

GO:0023052

GO:0034330

GO:0034332

GO:0035249

GO:0042802

GO:0043083

GO:0043679

GO:0044331

GO:0045296

GO:0046872

GO:0048870

GO:0050807

GO:0097060

GO:0098609

GO:0098978

HMNXSV003038327

Hs.288169.0.A1_3p_at

Hs.298050.0.A1_3p_at

Hs.79133.1.S1_3p_at

ILMN_1757020

L34060_at

PH_hs_0024487

TC16001161.hg

g6483314_3p_at

Participates

as a member of

Classic Cadherin [plasma membrane] (Homo sapiens)

as a component of

CDH8:CTNDD1:CTNNB1/JUP:CTNNA1 [plasma membrane] (Homo sapiens)

Inferred To

CDH8 [plasma membrane] (Bos taurus)

CDH8 [plasma membrane] (Canis familiaris)

CDH8 [plasma membrane] (Gallus gallus)

CDH8 [plasma membrane] (Sus scrofa)

cdh8 [plasma membrane] (Xenopus tropicalis)

Cdh8 [plasma membrane] (Mus musculus)

Cdh8 [plasma membrane] (Rattus norvegicus)

CadN2 [plasma membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_001787.2

ENSEMBL

ENST00000577390, ENSP00000462701

OpenTargets

ENSG00000150394

HPA

ENSG00000150394-CDH8

PRO

P55286

Pharos - Targets

P55286

GlyGen

P55286

HMDB Protein

HMDBP07524

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P35222 CTNNB1	20	CTNNB1 S45A [cytosol] (R-HSA-9663982) CTNNB1 S45F [cytosol] (R-HSA-4791268) CTNNB1 S45C [cytosol] (R-HSA-9663983) CTNNB1 S45Y [cytosol] (R-HSA-9663975) CTNNB1 S45N [cytosol] (R-HSA-9663984) CTNNB1 S45P [cytosol] (R-HSA-4791272) pT41,S45-CTNNB1 S37P [cytosol] (R-HSA-9663981) pT41,S45-CTNNB1 S37F [cytosol] (R-HSA-4839621) CTNNB1 [nucleoplasm] (R-HSA-3451168) CTNNB1 [cytosol] (R-HSA-448839) CTNNB1(1-115) [cytosol] (R-HSA-202930) CTNNB1(116-376) [cytosol] (R-HSA-202950) CTNNB1 [plasma membrane] (R-HSA-9038440) p-S33,S37,T41,S45 CTNNB1 [cytosol] (R-HSA-8942374) p-S37,T41,S45, CTNNB1 [cytosol] (R-HSA-8942369) p-T41,S45 CTNNB1 [cytosol] (R-HSA-8942367) p-S45 CTNNB1 [cytosol] (R-HSA-8942363) p-S552-CTNNB1 [cytosol] (R-HSA-3134933) p-S552-CTNNB1 [nucleoplasm] (R-HSA-3134926) p-Y-CTNNB1 [cytosol] (R-HSA-8876940)	0.527	3
UniProt:P29597 TYK2	5	p-Y1054-TYK2 [cytosol] (R-HSA-1112598) p-Y1054,Y1055-TYK2 [cytosol] (R-HSA-909682) TYK2 [cytosol] (R-HSA-877348) p-Y-TYK2 [cytosol] (R-HSA-6784366) p-TYK2 [cytosol] (R-HSA-8950424)	0.527	2

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