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VIP(125-152) [extracellular region]
Stable Identifier
R-HSA-420208
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
VIP, Vasoactive intestinal peptide, VIP_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
VIPR1,VIPR2:VIP(125-152) [plasma membrane] (Homo sapiens)
VIP(125-152) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
VIPR1,VIPR2:VIP(125-152) [plasma membrane] (Homo sapiens)
VIP(125-152) [extracellular region] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
VIPR1,VIPR2:VIP(125-152) [plasma membrane] (Homo sapiens)
VIP(125-152) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
VIPR1,VIPR2:VIP(125-152) [plasma membrane] (Homo sapiens)
VIP(125-152) [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
VIPR1,VIPR2:VIP(125-152) [plasma membrane] (Homo sapiens)
VIP(125-152) [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gs [extracellular region] (Homo sapiens)
VIP(125-152) [extracellular region] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class B/2 (Secretin family receptors) (Homo sapiens)
Glucagon-type ligand receptors (Homo sapiens)
VIP receptors bind VIP (Homo sapiens)
VIP(125-152) [extracellular region] (Homo sapiens)
VIPR1,VIPR2:VIP(125-152) [plasma membrane] (Homo sapiens)
VIP(125-152) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01282 VIP
Gene Names
VIP
Chain
signal peptide:1-20, propeptide:21-79, peptide:81-122, peptide:81-107, peptide:125-152, propeptide:156-170
Reference Genes
BioGPS Gene:7432 VIP
COSMIC (genes):VIP VIP
CTD Gene:7432 VIP
dbSNP Gene:7432 VIP
ENSEMBL:ENSG00000146469 VIP
ENSEMBL_homo_sapiens_GENE:ENSG00000146469.13 VIP
HGNC:12693 VIP
KEGG Gene (Homo sapiens):7432 VIP
Monarch:7432 VIP
NCBI Gene:7432 VIP
OMIM:192320 VIP
UCSC:P01282 VIP
Reference Transcript
RefSeq:NM_194435.2 VIP
RefSeq:NM_003381.3 VIP
Other Identifiers
11733966_at
11733967_at
17013856
206577_PM_at
206577_at
2931996
2931997
2931998
2931999
2932001
2932002
2932003
2932004
2932005
2932006
2932008
2932009
334_s_at
33567_at
7432
8122865
A_23_P19650
GE57953
GO:0001938
GO:0005102
GO:0005179
GO:0005184
GO:0005515
GO:0005576
GO:0007186
GO:0007189
GO:0007200
GO:0007589
GO:0007611
GO:0008284
GO:0012501
GO:0016071
GO:0022414
GO:0023052
GO:0030163
GO:0032812
GO:0032879
GO:0032880
GO:0043005
GO:0043066
GO:0043267
GO:0045732
GO:0048018
GO:0048242
GO:0048255
GO:0048662
GO:0050877
GO:0051428
GO:0060406
GO:0070459
GO:0098772
HMNXSV003054049
ILMN_1794638
ILMN_2357542
M36634_at
PH_hs_0028906
TC06001110.hg
g4507896_3p_at
Participates
as an input of
VIP receptors bind VIP (Homo sapiens)
as a member of
Ligands of GPCRs that activate Gs [extracellular region] (Homo sapiens)
as a component of
VIPR1,VIPR2:VIP(125-152) [plasma membrane] (Homo sapiens)
Inferred To
VIP [extracellular region]
(Bos taurus)
VIP [extracellular region]
(Canis familiaris)
VIP [extracellular region]
(Gallus gallus)
VIP [extracellular region]
(Sus scrofa)
vip [extracellular region]
(Xenopus tropicalis)
Vip [extracellular region]
(Mus musculus)
Vip [extracellular region]
(Rattus norvegicus)
Cross References
RefSeq
NP_003372.1
,
NP_919416.1
OpenTargets
ENSG00000146469
GeneCards
P01282
HPA
ENSG00000146469-VIP
Ensembl
ENST00000367244
,
ENST00000367243
,
ENSP00000356213
,
ENSP00000356212
,
ENSG00000146469
PRO
P01282
Pharos - Targets
P01282
HMDB Protein
HMDBP12707
PDB
2RRH
,
8E3Z
,
2RRI
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O43765 SGTA
1
SGTA [cytosol]
(R-HSA-5423595)
0.556
3
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