Reactome | MPP1 [plasma membrane]

MPP1 [plasma membrane]

Stable Identifier

R-HSA-420423

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

55 kDa erythrocyte membrane protein, EM55_HUMAN, p55

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q00013 MPP1

Gene Names

MPP1, DXS552E, EMP55

Chain

initiator methionine:1, chain:2-466

Reference Genes

BioGPS Gene:4354 MPP1

COSMIC (genes):MPP1 MPP1

CTD Gene:4354 MPP1

dbSNP Gene:4354 MPP1

ENSEMBL:ENSG00000130830.15 MPP1

HGNC:7219 MPP1

KEGG Gene (Homo sapiens):4354 MPP1

Monarch:4354 MPP1

NCBI Gene:4354 MPP1

OMIM:305360 MPP1

UCSC:Q00013 MPP1

Reference Transcript

Other Identifiers

0007040369

11722558_x_at

11745504_a_at

11746893_a_at

11746894_x_at

11752958_a_at

17115692

202974_PM_at

202974_at

32207_at

4027587

4027588

4027589

4027590

4027591

4027592

4027593

4027594

4027596

4027598

4027600

4027602

4027603

4027604

4027605

4027607

4027608

4027609

4027611

4027620

4027621

4027622

4354

8176174

A_23_P171296

A_33_P3247858

GE58289

GO:0002376

GO:0004385

GO:0005102

GO:0005515

GO:0005622

GO:0005737

GO:0005815

GO:0005856

GO:0005886

GO:0005911

GO:0007165

GO:0016020

GO:0016740

GO:0023052

GO:0030863

GO:0032420

GO:0034451

GO:0042995

GO:0043226

GO:0046037

GO:0046710

GO:0048870

GO:0055086

GO:0090022

GO:1901135

HMNXSV003056743

ILMN_1733675

M64925_at

PH_hs_0025154

TC0X001544.hg

g6006024_3p_at

Participates

as a component of

Outer hair cell stereocilium tip [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001159932.1, NP_001159934.1, NP_002427.1, NP_001159933.1

OpenTargets

ENSG00000130830

GeneCards

Q00013

HPA

ENSG00000130830-MPP1

Ensembl

ENSG00000130830, ENSP00000358547, ENSP00000400155, ENSP00000377165, ENST00000393531, ENST00000413259, ENST00000369534

PRO

Q00013

Pharos - Targets

Q00013

PDB

3NEY, 2EJY, 2EV8

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O15439 ABCC4	2	ABCC4 [platelet dense granule membrane] (R-HSA-391972) ABCC4 [plasma membrane] (R-HSA-1454927)	0.707	10
UniProt:Q96CW1 AP2M1	6	AP2M1 [plasma membrane] (R-HSA-167585) AP2M1 [lysosomal membrane] (R-HSA-196144) AP2M1 [cytosol] (R-HSA-182227) AP2M1 [clathrin-coated endocytic vesicle membrane] (R-HSA-2130423) AP2M1 [endolysosome membrane] (R-HSA-6784828) p-T156 AP2M1 [cytosol] (R-HSA-8856805)	0.556	5
UniProt:P06396 GSN	7	GSN(200-270) [extracellular region] (R-HSA-976940) GSN [secretory granule lumen] (R-HSA-6801486) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3
UniProt:Q9NRZ7 AGPAT3	2	AGPAT3 [Golgi membrane] (R-HSA-8849239) AGPAT3 [endoplasmic reticulum membrane] (R-HSA-61807)	0.556	3
UniProt:Q6ZPD8 DGAT2L6	1	DGAT2L6 [endoplasmic reticulum membrane] (R-HSA-8848588)	0.556	3
UniProt:Q9UBK9 UXT	1	UXT [nucleoplasm] (R-HSA-9007484)	0.556	3
UniProt:Q8TDN7 ACER1	1	ACER1 [endoplasmic reticulum membrane] (R-HSA-428221)	0.556	3
UniProt:Q96CV9 OPTN	5	OPTN [recycling endosome membrane] (R-HSA-8854141) p-S177-OPTN [nucleoplasm] (R-HSA-2562595) p-S177-OPTN [cytosol] (R-HSA-2562525) OPTN [Golgi membrane] (R-HSA-2161111) OPTN [cytosol] (R-HSA-9687907)	0.499	2

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