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Cleavage of intergenic spacer RNA to yield fragments of 150-300 nucleotides
Stable Identifier
R-HSA-427394
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Negative epigenetic regulation of rRNA expression (Homo sapiens)
NoRC negatively regulates rRNA expression (Homo sapiens)
Cleavage of intergenic spacer RNA to yield fragments of 150-300 nucleotides (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
As inferred from mouse cell models, long Intergenic Spacer RNA of about 2 Kb is cleaved to yield shorter fragments of 150-300 nucleotides. The enzyme responsible for the cleavage is unknown.
Participants
Input
Intergenic rRNA transcript [nucleoplasm]
(Homo sapiens)
Output
pRNA (intergenic rRNA) [nucleoplasm]
(Homo sapiens)
Participates
as an event of
NoRC negatively regulates rRNA expression (Homo sapiens)
Inferred From
Cleavage of intergenic spacer RNA to yield fragments of 150-300 nucleotides (Mus musculus)
Authored
May, B (2009-06-19)
Reviewed
Shiao, YH (2014-02-18)
Created
May, B (2009-06-20)
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