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SLC15A1 [plasma membrane]
Stable Identifier
R-HSA-428022
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
PEPT1, Solute carrier family 15 member 1, S15A1_HUMAN, Peptide transporter 1
Icon
Locations in the PathwayBrowser for interactor UniProt:Q96DA2 RAB39B
Expand all
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
Proton/oligopeptide cotransporters (Homo sapiens)
SLC25A1 transports di-/tri-peptides and peptide-like drugs (Homo sapiens)
SLC15A1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P46059 SLC15A1
Gene Names
SLC15A1, PEPT1
Chain
chain:1-708
Reference Genes
BioGPS Gene:6564 SLC15A1
COSMIC (genes):SLC15A1 SLC15A1
CTD Gene:6564 SLC15A1
dbSNP Gene:6564 SLC15A1
ENSEMBL:ENSG00000088386 SLC15A1
HGNC:10920 SLC15A1
KEGG:hsa:6564 SLC15A1
Monarch:6564 SLC15A1
NCBI Gene:6564 SLC15A1
OMIM:600544 SLC15A1
UCSC:P46059 SLC15A1
Reference Transcript
RefSeq:NM_005073.3 SLC15A1
Other Identifiers
11735143_at
11752275_a_at
11762662_at
16780481
207254_PM_at
207254_at
211349_PM_at
211349_at
31628_at
32906_at
3522339
3522340
3522341
3522342
3522344
3522347
3522348
3522349
3522354
3522355
3522357
3522359
3522361
3522362
3522363
3522364
3522365
3522367
3522368
3522369
3522370
3522371
3522372
3522373
3522374
3522375
3522376
3522377
3522378
3522379
3522386
6564
7972461
A_23_P128609
A_24_P8165
A_33_P3373273
GE59010
GO:0005215
GO:0005427
GO:0005886
GO:0005903
GO:0006811
GO:0006857
GO:0015031
GO:0015293
GO:0015333
GO:0015833
GO:0016020
GO:0016324
GO:0022857
GO:0035673
GO:0042937
GO:0055085
GO:0071916
GO:0140206
GO:0140207
GO:1902600
HMNXSV003030467
HMNXSV003046981
PH_hs_0026493
TC13000824.hg
U21936_at
g2506042_3p_at
g4827007_3p_at
Inferred To
Homologues of SLC15A1 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SLC15A1 [plasma membrane]
(Dictyostelium discoideum)
Homologues of SLC15A1 [plasma membrane]
(Drosophila melanogaster)
PEPT1 [plasma membrane]
(Gallus gallus)
pept-3 [plasma membrane]
(Caenorhabditis elegans)
CG32780 [plasma membrane]
(Drosophila melanogaster)
SLC15A1 [plasma membrane]
(Bos taurus)
SLC15A1 [plasma membrane]
(Canis familiaris)
SLC15A1 [plasma membrane]
(Dictyostelium discoideum)
SLC15A1 [plasma membrane]
(Sus scrofa)
Slc15a1 [plasma membrane]
(Mus musculus)
Slc15a1 [plasma membrane]
(Rattus norvegicus)
yin [plasma membrane]
(Drosophila melanogaster)
Dmel\CG9444 [plasma membrane]
(Drosophila melanogaster)
pept-1 [plasma membrane]
(Caenorhabditis elegans)
slc15a1b [plasma membrane]
(Danio rerio)
pept-2 [plasma membrane]
(Caenorhabditis elegans)
Cross References
Guide to Pharmacology - Targets
984
OpenTargets
ENSG00000088386
ENSEMBL
ENST00000376503
,
ENSG00000088386
,
ENSP00000365686
ZINC - Substances
S15A1_HUMAN
ZINC - Biogenic
S15A1_HUMAN
ZINC target
P46059
PRO
P46059
GlyGen
P46059
PDB
7PMW
,
7PMX
,
7PN1
ZINC - Metabolites
S15A1_HUMAN
HPA
ENSG00000088386-SLC15A1
GeneCards
SLC15A1
Pharos - Targets
P46059
ZINC - Predictions - Purchasable
S15A1_HUMAN
HMDB Protein
HMDBP02749
Interactors (26)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P23458 JAK1
6
p-Y-JAK1 [cytosol]
(R-HSA-451921)
JAK1 [cytosol]
(R-HSA-451898)
p-Y1034-JAK1 [cytosol]
(R-HSA-1112543)
p-JAK1 [cytosol]
(R-HSA-8950711)
JAK1 [endosome]
(R-HSA-8983168)
p-Y1034,Y1035-JAK1 [cytosol]
(R-HSA-9005335)
0.527
2
UniProt:P24468 NR2F2
1
NR2F2 [nucleoplasm]
(R-HSA-1183002)
0.527
2
UniProt:Q6UXV4 APOOL
3
APOOL (MIC27) [mitochondrial inner membrane]
(R-HSA-8949612)
APOOL [extracellular region]
(R-HSA-8862979)
APOOL [platelet alpha granule lumen]
(R-HSA-8863003)
0.527
2
UniProt:P33897 ABCD1
8
ABCD1 [peroxisomal membrane]
(R-HSA-382566)
ABCD1 [cytosol]
(R-HSA-382587)
ABCD1 G277R [peroxisomal membrane]
(R-HSA-5685058)
ABCD1 M1V [peroxisomal membrane]
(R-HSA-5685059)
ABCD1 R554H [peroxisomal membrane]
(R-HSA-5685072)
ABCD1 S606L [peroxisomal membrane]
(R-HSA-5685104)
ABCD1 T77_L82del [peroxisomal membrane]
(R-HSA-5685088)
ABCD1 R617C [peroxisomal membrane]
(R-HSA-5685069)
0.527
2
UniProt:Q8NE86 MCU
1
MCU [mitochondrial inner membrane]
(R-HSA-8949184)
0.527
2
UniProt:P20337 RAB3B
2
GGC-RAB3B [cytosol]
(R-HSA-8874009)
RAB3B [cytosol]
(R-HSA-8873715)
0.527
2
UniProt:B0YJ81 HACD1
1
PTPLA [endoplasmic reticulum membrane]
(R-HSA-5676076)
0.527
2
UniProt:Q96E52 OMA1
3
OMA1(144-447) [mitochondrial inner membrane]
(R-HSA-9840539)
OMA1(144-524) [mitochondrial inner membrane]
(R-HSA-9840540)
OMA1 [mitochondrial inner membrane]
(R-HSA-8867510)
0.527
2
UniProt:Q9BWM7 SFXN3
0.527
2
UniProt:Q9NR77 PXMP2
2
PXMP2 [cytosol]
(R-HSA-9603794)
PXMP2 [peroxisomal membrane]
(R-HSA-8953432)
0.527
2
UniProt:Q8TD22 SFXN5
0.527
2
UniProt:A6ZKI3 RTL8C
0.527
2
UniProt:O14981 BTAF1
0.527
2
UniProt:Q86Y56 DAAF5
0.527
2
UniProt:P50748 KNTC1
1
KNTC1 [cytosol]
(R-HSA-376233)
0.527
2
UniProt:P84085 ARF5
1
ARF5 [cytosol]
(R-HSA-6807737)
0.527
2
UniProt:Q96DA2 RAB39B
3
GGC-RAB39B [Golgi membrane]
(R-HSA-8877796)
GGC-RAB39B [cytosol]
(R-HSA-8874006)
RAB39B [cytosol]
(R-HSA-8873679)
0.527
2
UniProt:Q02338 BDH1
1
BDH1 [mitochondrial matrix]
(R-HSA-73922)
0.527
2
UniProt:Q96DA6 DNAJC19
1
DNAJC19 [mitochondrial inner membrane]
(R-HSA-1252127)
0.527
2
UniProt:Q14849 STARD3
1
STARD3 [cytosol]
(R-HSA-5216089)
0.527
2
UniProt:A6NJ78 MET15
0.527
2
UniProt:Q96A46 SLC25A28
1
SLC25A28 [mitochondrial inner membrane]
(R-HSA-1362394)
0.527
2
UniProt:Q96BW9 TAM41
0.527
2
UniProt:P68366 TUBA4A
9
TUBA4A [cytosol]
(R-HSA-191694)
TUBA4A [axonemal microtubule]
(R-HSA-5610443)
TUBA4A [extracellular region]
(R-HSA-350734)
Polyglutamyl-TUBA4A [cytosol]
(R-HSA-8867386)
L-isoglutamyl polyglycyl-TUBA4A [cytosol]
(R-HSA-8867378)
TUBA4A unfolded [cytosol]
(R-HSA-392771)
TUBA4A folding intermediate [cytosol]
(R-HSA-392800)
Ac K40 TUBA4A [axonemal microtubule]
(R-HSA-5624859)
AcK-TUBA4A [cytosol]
(R-HSA-5618318)
0.527
2
UniProt:P0C0L4 C4A
11
dNQ-C4A(757-1446) [extracellular region]
(R-HSA-2855053)
C4A(1454-1744) [extracellular region]
(R-HSA-166731)
C4A(20-675) [extracellular region]
(R-HSA-166734)
S-(L-isoglutamyl)-L-cysteine-C4A(757-1446) [extracellular region]
(R-HSA-166736)
C4 alpha [extracellular region]
(R-HSA-166729)
C4A-derived C4a [extracellular region]
(R-HSA-166737)
C4A(956-1336) [plasma membrane]
(R-HSA-981501)
C4A alpha3 [extracellular region]
(R-HSA-981503)
C4A alpha4 fragment [extracellular region]
(R-HSA-981506)
C4A [endoplasmic reticulum lumen]
(R-HSA-8956717)
p-C4A [endoplasmic reticulum lumen]
(R-HSA-8956932)
0.527
2
UniProt:Q29RF7 PDS5A
4
PDS5A [cytosol]
(R-HSA-2484799)
PDS5A [chromosome]
(R-HSA-2466360)
PDS5A [chromosome, centromeric region]
(R-HSA-2468259)
PDS5A [nucleoplasm]
(R-HSA-2468043)
0.527
2
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