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CERS3 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-428159
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
LASS3, LAG1 homolog, ceramide synthase 3
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Sphingolipid metabolism (Homo sapiens)
Sphingolipid de novo biosynthesis (Homo sapiens)
Ceramide synthases transfer acyl-CoA onto sphingoid (Homo sapiens)
Ceramide synthases [endoplasmic reticulum membrane] (Homo sapiens)
CERS3 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IU89 CERS3
Gene Names
CERS3, LASS3
Chain
chain:1-383
Reference Genes
BioGPS Gene:204219 CERS3
COSMIC (genes):CERS3 CERS3
CTD Gene:204219 CERS3
dbSNP Gene:204219 CERS3
ENSEMBL:ENSG00000154227 CERS3
ENSEMBL_homo_sapiens_GENE:ENSG00000154227.14 CERS3
HGNC:23752 CERS3
KEGG Gene (Homo sapiens):204219 CERS3
Monarch:204219 CERS3
NCBI Gene:204219 CERS3
OMIM:615276 CERS3
UCSC:Q8IU89 CERS3
Reference Transcript
RefSeq:XM_017022004.1 CERS3
RefSeq:NM_178842.4 CERS3
RefSeq:NM_001290342.2 CERS3
RefSeq:XM_017022003.1 CERS3
RefSeq:NM_001290343.1 CERS3
RefSeq:NM_001290341.2 CERS3
Other Identifiers
11734264_at
11755423_a_at
1554252_PM_a_at
1554252_a_at
1554253_PM_a_at
1554253_a_at
16813799
204219
3641778
3641779
3641780
3641788
3641791
3641792
3641794
3641795
3641796
3641797
3641798
3641799
3641803
3641807
3641808
3641812
3641813
3641814
3641815
3641816
3641817
75414_at
7991546
A_24_P943017
A_33_P3408305
GO:0003677
GO:0003824
GO:0005515
GO:0005783
GO:0005789
GO:0006629
GO:0006665
GO:0008544
GO:0012501
GO:0016020
GO:0016740
GO:0030148
GO:0030154
GO:0030216
GO:0043226
GO:0046513
GO:0048856
GO:0050291
GO:0070268
HMNXSV003026855
Hs2.97965.1.S1_3p_s_at
Hs2.97965.1.S2_3p_s_at
ILMN_1743142
PH_hs_0025042
TC15001996.hg
Participates
as a member of
Ceramide synthases [endoplasmic reticulum membrane] (Homo sapiens)
Inferred To
crsA [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
cers3 [endoplasmic reticulum membrane]
(Xenopus tropicalis)
LAG1 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
cers2 [endoplasmic reticulum membrane]
(Xenopus tropicalis)
schlank [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Homologues of CERS3 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Homologues of CERS3 [endoplasmic reticulum membrane]
(Danio rerio)
Homologues of CERS3 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
Homologues of CERS3 [endoplasmic reticulum membrane]
(Schizosaccharomyces pombe)
Homologues of CERS3 [endoplasmic reticulum membrane]
(Xenopus tropicalis)
LAC1 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
lag1 [endoplasmic reticulum membrane]
(Schizosaccharomyces pombe)
cers2a [endoplasmic reticulum membrane]
(Danio rerio)
CERS3 [endoplasmic reticulum membrane]
(Bos taurus)
CERS3 [endoplasmic reticulum membrane]
(Canis familiaris)
CERS3 [endoplasmic reticulum membrane]
(Gallus gallus)
CERS3 [endoplasmic reticulum membrane]
(Plasmodium falciparum)
CERS3 [endoplasmic reticulum membrane]
(Sus scrofa)
cers2b [endoplasmic reticulum membrane]
(Danio rerio)
lac1 [endoplasmic reticulum membrane]
(Schizosaccharomyces pombe)
Cers3 [endoplasmic reticulum membrane]
(Mus musculus)
Cers3 [endoplasmic reticulum membrane]
(Rattus norvegicus)
hyl-2 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
hyl-1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001277271.1
,
NP_001277270.1
,
XP_016877493.1
,
NP_849164.2
,
NP_001277272.1
,
XP_016877492.1
Guide to Pharmacology - Targets
2476
OpenTargets
ENSG00000154227
IntEnz
2.3.1.297
,
2.3.1.298
,
2.3.1.24
GeneCards
Q8IU89
HPA
ENSG00000154227-CERS3
Ensembl
ENST00000394113
,
ENSP00000506641
,
ENST00000679737
,
ENSP00000284382
,
ENST00000284382
,
ENSP00000437640
,
ENST00000538112
,
ENSP00000377672
,
ENSG00000154227
PRO
Q8IU89
Pharos - Targets
Q8IU89
Orphanet
22372
HMDB Protein
HMDBP11631
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