Reactome | PARVA [cytosol]

PARVA [cytosol]

Stable Identifier

R-HSA-432848

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

CH-ILKBP, Alpha-parvin, PARVA_HUMAN, actopaxin

Locations in the PathwayBrowser for interactor UniProt:P54252 ATXN3

Expand all

External Reference Information

External Reference

UniProt:Q9NVD7 PARVA

Gene Names

PARVA, MXRA2

Chain

initiator methionine:, chain:2-372

Reference Genes

BioGPS Gene:55742 PARVA

COSMIC (genes):PARVA PARVA

CTD Gene:55742 PARVA

dbSNP Gene:55742 PARVA

ENSEMBL:ENSG00000197702 PARVA

ENSEMBL_homo_sapiens_GENE:ENSG00000197702.14 PARVA

HGNC:14652 PARVA

KEGG Gene (Homo sapiens):55742 PARVA

Monarch:55742 PARVA

NCBI Gene:55742 PARVA

OMIM:608120 PARVA

Reference Transcript

RefSeq:NM_018222.4 PARVA

Other Identifiers

11721080_at

11721081_at

11751491_a_at

11758841_s_at

16722162

213675_PM_at

213675_at

217890_PM_s_at

217890_s_at

222454_PM_s_at

222454_s_at

222455_PM_s_at

222455_s_at

235279_PM_at

235279_at

3320867

3320868

3320869

3320870

3320887

3320888

3320889

3320895

3320900

3320902

3320904

3320909

3320910

3320912

3320913

3320919

3320920

3320921

3320922

3320923

3320924

3320925

3320926

3320927

3320928

3320929

3320930

3320931

3320932

39750_at

46204_at

52345_s_at

55742

57185_at

7938528

85597_at

A_14_P102805

A_23_P47642

A_24_P124370

A_24_P931944

A_32_P76536

GE55862

GE874979

GO:0001525

GO:0002040

GO:0003148

GO:0003779

GO:0004860

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0005925

GO:0006935

GO:0007010

GO:0007155

GO:0007163

GO:0008092

GO:0008360

GO:0015629

GO:0016020

GO:0030018

GO:0030027

GO:0030030

GO:0030036

GO:0034113

GO:0034446

GO:0043226

GO:0044782

GO:0045296

GO:0048856

GO:0048870

GO:0050821

GO:0060271

GO:0070161

GO:0070252

GO:0071670

GO:0098772

HMNXSV003015480

Hs.14896.1.S1_3p_at

Hs.189752.0.A1_3p_at

Hs.44077.0.A1_3p_a_at

PH_hs_0003199

PH_hs_0020063

TC11000201.hg

TC11002563.hg

g11036539_3p_a_at

g8922672_3p_a_at

Participates

as a component of

as an input of

as a candidate of

alpha/beta parvin [cytosol] (Homo sapiens)

Inferred To

PARVA [cytosol] (Bos taurus)

PARVA [cytosol] (Canis familiaris)

PARVA [cytosol] (Gallus gallus)

PARVA [cytosol] (Sus scrofa)

parva [cytosol] (Xenopus tropicalis)

parvin [cytosol] (Drosophila melanogaster)

Parva [cytosol] (Mus musculus)

Parva [cytosol] (Rattus norvegicus)

parvaa [cytosol] (Danio rerio)

pat-6 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_060692.2

OpenTargets

ENSG00000197702

HPA

ENSG00000197702-PARVA

GeneCards

Q9NVD7

Ensembl

ENST00000334956, ENSP00000334008, ENSG00000197702

PRO

Q9NVD7

Pharos - Targets

Q9NVD7

PDB

2VZI, 3REP, 3KMW, 2VZD, 2K2R, 2VZG, 2VZC, 3KMU, 6MIB

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13418 ILK	1	ILK [cytosol] (R-HSA-432864)	0.97	27
UniProt:Q96EN8 MOCOS	1	PXLP-K264-MOCOS [cytosol] (R-HSA-947549)	0.801	6
UniProt:P48059 LIMS1	1	LIMS1 [cytosol] (R-HSA-432859)	0.643	4
UniProt:Q9H0I2 ENKD1			0.556	3
UniProt:P54252 ATXN3	2	ATXN3 [nucleoplasm] (R-HSA-6783285) ATXN3 [cytosol] (R-HSA-5625607)	0.556	9
UniProt:O60711 LPXN			0.527	2
UniProt:P46940 IQGAP1	3	IQGAP1 [cytosol] (R-HSA-5626371) IQGAP1 [secretory granule membrane] (R-HSA-6804803) IQGAP1 [plasma membrane] (R-HSA-381681)	0.527	2
UniProt:Q9H270 VPS11	1	VPS11 [endosome membrane] (R-HSA-2197802)	0.527	2
UniProt:Q15404 RSU1	1	RSU1 [cytosol] (R-HSA-446297)	0.527	3
UniProt:Q9HBI1 PARVB	1	PARVB [cytosol] (R-HSA-446016)	0.527	2
UniProt:P14635 CCNB1	4	CCNB1 [nucleoplasm] (R-HSA-68901) p-4S-CCNB1 [cytosol] (R-HSA-170058) p-4S-CCNB1 [nucleoplasm] (R-HSA-170049) CCNB1 [cytosol] (R-HSA-157451)	0.527	2
UniProt:O55222	1	ILK [cytosol] (R-MMU-432864)	0.499	2
UniProt:Q14494-2 NFE2L1			0.488	2