Reactome | SNX9 [cytoplasmic vesicle membrane]

SNX9 [cytoplasmic vesicle membrane]

Stable Identifier

R-HSA-432990

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytoplasmic vesicle membrane

Synonyms

Sorting nexin-9, SNX9_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Y5X1 SNX9

Gene Names

SNX9, SH3PX1, SH3PXD3A

Chain

chain:1-595

Reference Genes

BioGPS Gene:51429 SNX9

COSMIC (genes):SNX9 SNX9

CTD Gene:51429 SNX9

dbSNP Gene:51429 SNX9

ENSEMBL:ENSG00000130340 SNX9

HGNC:14973 SNX9

Monarch:51429 SNX9

NCBI Gene:51429 SNX9

OMIM:605952 SNX9

UCSC:Q9Y5X1 SNX9

Reference Transcript

RefSeq:NM_016224.4 SNX9

Other Identifiers

11731784_a_at

11746543_a_at

11756208_a_at

17014087

17014091

223027_PM_at

223027_at

223028_PM_s_at

223028_s_at

2494795

2933330

2933332

2933338

2933339

2933341

2933342

2933346

2933349

2933353

2933354

2933355

2933358

2933362

2933364

2933366

2933368

2933371

2933372

2933373

2933374

2933375

2933376

2933377

2933378

2933379

2933380

2933381

2933382

2933383

2933384

2933385

2933386

2933387

46285_at

51429

51748_at

65579_at

8122986

A_21_P0005142

A_23_P214789

A_24_P179044

GE58706

GO:0000278

GO:0000281

GO:0000910

GO:0001726

GO:0005515

GO:0005545

GO:0005737

GO:0005794

GO:0005802

GO:0005829

GO:0005886

GO:0005905

GO:0006886

GO:0006897

GO:0006898

GO:0008289

GO:0015031

GO:0016020

GO:0016192

GO:0016197

GO:0030136

GO:0030659

GO:0030838

GO:0031410

GO:0031625

GO:0032437

GO:0035091

GO:0036089

GO:0042802

GO:0042803

GO:0042995

GO:0043226

GO:0043547

GO:0045296

GO:0045860

GO:0051044

GO:0051301

GO:0060988

GO:0061024

GO:0065003

GO:0070062

GO:0071933

GO:0097320

GO:0098793

GO:1900242

HMNXSV003053337

HMNXSV003058447

Hs.7905.0.S2_3p_at

ILMN_1726366

PH_hs_0000815

TC06001126.hg

TC06003151.hg

TC06003152.hg

g13477130_3p_a_at

p23569

Participates

as a candidate of

Golgi-associated Vesicle Cargo [cytoplasmic vesicle membrane] (Homo sapiens)

Other forms of this molecule

SNX9 [cytosol]

SNX9 [Golgi membrane]

Inferred To

lst-4 [cytoplasmic vesicle membrane] (Caenorhabditis elegans)

SNX9 [cytoplasmic vesicle membrane] (Bos taurus)

SNX9 [cytoplasmic vesicle membrane] (Canis familiaris)

SNX9 [cytoplasmic vesicle membrane] (Drosophila melanogaster)

SNX9 [cytoplasmic vesicle membrane] (Gallus gallus)

SNX9 [cytoplasmic vesicle membrane] (Mus musculus)

SNX9 [cytoplasmic vesicle membrane] (Rattus norvegicus)

SNX9 [cytoplasmic vesicle membrane] (Sus scrofa)

SNX9 [cytoplasmic vesicle membrane] (Xenopus tropicalis)

Cross References

ENSEMBL

ENST00000679814, ENSP00000376024, ENST00000392185, ENSP00000506326

OpenTargets

ENSG00000130340

HPA

ENSG00000130340-SNX9

PRO

Q9Y5X1

Pharos - Targets

Q9Y5X1

GlyGen

Q9Y5X1

PDB

3DYU, 3LGE, 2RAI, 2RAJ, 2RAK, 7OJ9, 3DYT

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P50570 DNM2	5	DNM2 [Golgi membrane] (R-HSA-2980842) DNM2 [endocytic vesicle membrane] (R-HSA-2029000) DNM2 [cytosol] (R-HSA-2213180) DNM2 [lysosomal membrane] (R-HSA-2980840) DNM2 [plasma membrane] (R-HSA-2984201)	0.887	11
UniProt:Q05193 DNM1	3	DNM1 [plasma membrane] (R-HSA-177488) DNM1 [lysosomal membrane] (R-HSA-196150) DNM1 [cytosol] (R-HSA-2213182)	0.825	6
UniProt:Q96J02 ITCH	2	Ub-C871-ITCH [cytosol] (R-HSA-8864515) ITCH [cytosol] (R-HSA-975995)	0.623	7
UniProt:P42768 WAS	2	p-Y291-WAS [cytosol] (R-HSA-2197668) WAS [cytosol] (R-HSA-201879)	0.573	2
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2
UniProt:O14965 AURKA	6	p-T288-AURKA [cytosol] (R-HSA-2574832) AURKA [cytosol] (R-HSA-174254) p-T288-AURKA [nucleoplasm] (R-HSA-6805089) AURKA [nucleoplasm] (R-HSA-4655443) PolyUb-AURKA [cytosol] (R-HSA-8854040) SUMO1-K258-AURKA [cytosol] (R-HSA-4655367)	0.527	3
UniProt:Q7L190 DPPA4	1	DPPA4 [nucleoplasm] (R-HSA-452999)	0.527	2
UniProt:Q07889 SOS1	3	SOS1 [cytosol] (R-HSA-64847) SOS1 [plasma membrane] (R-HSA-983559) p-4S-SOS1 [cytosol] (R-HSA-109821)	0.524	2
UniProt:O00401 WASL	4	p-Y256-WASL [cytosol] (R-HSA-2197672) N-WASP [cytosol] (R-HSA-201873) WASL [plasma membrane] (R-HSA-203010) WASL [endocytic vesicle membrane] (R-HSA-535012)	0.524	2
UniProt:P48023 FASLG	1	FASLG(1-281) [extracellular region] (R-HSA-66212)	0.524	2
UniProt:P0CG48 UBC	20	UBC(381-456) [endocytic vesicle membrane] (R-HSA-939218) UBC(533-608) [endocytic vesicle membrane] (R-HSA-939220) UBC(609-684) [endocytic vesicle membrane] (R-HSA-939223) UBC(457-532) [endocytic vesicle membrane] (R-HSA-939195) UBC(153-228) [endocytic vesicle membrane] (R-HSA-939194) UBC(305-380) [endocytic vesicle membrane] (R-HSA-939228) UBC(229-304) [endocytic vesicle membrane] (R-HSA-939177) UBC(77-152) [endocytic vesicle membrane] (R-HSA-939210) UBC(1-76) [endocytic vesicle membrane] (R-HSA-939245) Ub-565-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783166) Ub-337-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783121) Ub-185-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783154) Ub-261-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783028) Ub-413-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783061) Ub-109-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783158) Ub-641-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783182) Ub-33-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783073) Ub-489-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783078) Ub-291-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783193) Ub-595-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783130)	0.499	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	7

Cite Us!