Reactome | SLC10A6 [plasma membrane]

SLC10A6 [plasma membrane]

Stable Identifier

R-HSA-433091

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

SOAT, Solute carrier family 10 member 6, SOAT_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q3KNW5 SLC10A6

Gene Names

SLC10A6, SOAT

Chain

chain:1-377

Reference Genes

BioGPS Gene:345274 SLC10A6

COSMIC (genes):SLC10A6 SLC10A6

CTD Gene:345274 SLC10A6

dbSNP Gene:345274 SLC10A6

ENSEMBL:ENSG00000145283 SLC10A6

ENSEMBL_homo_sapiens_GENE:ENSG00000145283.8 SLC10A6

HGNC:30603 SLC10A6

KEGG Gene (Homo sapiens):345274 SLC10A6

Monarch:345274 SLC10A6

NCBI Gene:345274 SLC10A6

OMIM:613366 SLC10A6

UCSC:Q3KNW5 SLC10A6

Reference Transcript

RefSeq:NM_197965.2 SLC10A6

Other Identifiers

11738425_at

16977760

2776839

2776840

2776841

2776842

2776843

2776844

2776846

2776847

2776848

345274

8101609

A_33_P3212102

GE489993

GO:0005215

GO:0005515

GO:0005886

GO:0006811

GO:0006814

GO:0006869

GO:0008508

GO:0015293

GO:0015721

GO:0016020

GO:0043250

GO:0043251

GO:0055085

HMNXSV003037610

ILMN_1792933

PH_hs_0030422

TC04001359.hg

Inferred To

slc10a6 [plasma membrane] (Xenopus tropicalis)

Dmel\CG11655 [plasma membrane] (Drosophila melanogaster)

SLC10A6 [plasma membrane] (Bos taurus)

SLC10A6 [plasma membrane] (Caenorhabditis elegans)

SLC10A6 [plasma membrane] (Canis familiaris)

SLC10A6 [plasma membrane] (Sus scrofa)

Slc10a6 [plasma membrane] (Mus musculus)

Slc10a6 [plasma membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_932069.1

Guide to Pharmacology - Targets

961

OpenTargets

ENSG00000145283

GeneCards

Q3KNW5

HPA

ENSG00000145283-SLC10A6

Ensembl

ENSP00000273905, ENSG00000145283, ENST00000273905

PRO

Q3KNW5

Pharos - Targets

Q3KNW5

HMDB Protein

HMDBP09095

Interactors (146)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15041 AR6P1			0.556	3
UniProt:Q9NZ01 TECR	1	TECR [endoplasmic reticulum membrane] (R-HSA-548663)	0.556	3
UniProt:Q6ZPD8 DGAT2L6	1	DGAT2L6 [endoplasmic reticulum membrane] (R-HSA-8848588)	0.556	3
UniProt:Q5RI15 COX20	1	COX20 [mitochondrial inner membrane] (R-HSA-5336169)	0.556	3
UniProt:O60636 TSN2			0.556	3
UniProt:Q13021 MALL			0.556	3
UniProt:Q92520 FAM3C	2	FAM3C [extracellular region] (R-HSA-8848922) FAM3C [platelet dense granule lumen] (R-HSA-8848884)	0.556	3
UniProt:Q9H2L4 TMM60			0.556	3
UniProt:Q96MV8 ZDH15			0.556	3
UniProt:B2RUZ4 SMIM1			0.556	3
UniProt:P78329 CYP4F2	1	CYP4F2 [endoplasmic reticulum membrane] (R-HSA-211016)	0.556	3
UniProt:A2RU14 TM218			0.556	3
UniProt:Q86Y82 STX12			0.556	3
UniProt:P57105 SYJ2B			0.556	3
UniProt:O14735 CDIPT	1	CDIPT [endoplasmic reticulum membrane] (R-HSA-1498749)	0.556	3
UniProt:Q9H0Q3 FXYD6	1	FXYD6 [plasma membrane] (R-HSA-2752104)	0.556	3
UniProt:Q99726 SLC30A3	1	SLC30A3 [synaptic vesicle membrane] (R-HSA-437087)	0.556	3
UniProt:Q8N661 TMEM86B	1	TMEM86B [endoplasmic reticulum membrane] (R-HSA-8874443)	0.556	3
UniProt:Q6N075 MFSD5			0.556	3
UniProt:P02808 STAT			0.556	3
UniProt:O95452 GJB6	1	GJB6 [endoplasmic reticulum membrane] (R-HSA-190633)	0.556	3
UniProt:Q9Y3D6 FIS1	2	FIS1 [peroxisomal membrane] (R-HSA-9033123) FIS1 [cytosol] (R-HSA-9033099)	0.556	3
UniProt:Q0VAQ4 SMAGP			0.556	3
UniProt:Q96F05 CK024			0.556	3
UniProt:Q96AG3 S2546			0.556	3
UniProt:Q9H9B4 SFXN1			0.556	3
UniProt:Q9NUM3 S39A9			0.556	3
UniProt:Q8IXM6 NRM			0.556	3
UniProt:Q7Z6L0 PRRT2			0.556	3
UniProt:O95562 SFT2B			0.556	3
UniProt:Q99650 OSMR	1	OSMR [plasma membrane] (R-HSA-448654)	0.556	3
UniProt:P05090 APOD	1	APOD [extracellular region] (R-HSA-5216199)	0.556	3
UniProt:Q9Y6G1 TM14A			0.556	3
UniProt:Q13433-2 SLC39A6			0.556	3
UniProt:Q86T03 TMEM55B	2	TMEM55B [late endosome membrane] (R-HSA-6810395) TMEM55B [nucleoplasm] (R-HSA-6810405)	0.556	3
UniProt:Q8N6L7 TM252			0.556	3
UniProt:O15400 STX7			0.556	3
UniProt:Q6UX40 TM107			0.556	3
UniProt:A0AVG3 A0AVG3			0.556	3
UniProt:Q9Y548 YIPF1			0.556	3
UniProt:Q969E2 SCAM4			0.556	3
UniProt:Q8TDV0 GP151			0.556	3
UniProt:Q8IVJ1 SLC41A1	1	SLC41A1 [plasma membrane] (R-HSA-442659)	0.556	3
UniProt:I3L0A0 I3L0A0			0.556	3
UniProt:Q9Y385 UBE2J1	1	UBE2J1 [cytosol] (R-HSA-947625)	0.556	3
UniProt:Q92903 CDS1	1	CDS1 [endoplasmic reticulum membrane] (R-HSA-1498762)	0.556	3
UniProt:P29400-2 COL4A5			0.556	3
UniProt:O43759-2 SYNGR1			0.556	3
UniProt:O95393 BMP10	2	BMP10(22-424) [extracellular region] (R-HSA-2396409) BMP10 [extracellular region] (R-HSA-8858374)	0.556	3
UniProt:Q9BTX3 TM208			0.556	3
UniProt:P48230 T4S4			0.556	3
UniProt:Q96GQ5 RUSF1			0.556	3
UniProt:E9PQX1 TM262			0.556	3
UniProt:O95159 ZFPL1			0.556	3
UniProt:P02787 TF	6	apoTF [clathrin-coated endocytic vesicle membrane] (R-HSA-8869140) TF [secretory granule lumen] (R-HSA-350704) apoTF [extracellular region] (R-HSA-350754) apoTF [endosome membrane] (R-HSA-917974) p-TF [endoplasmic reticulum lumen] (R-HSA-8957001) TF [endoplasmic reticulum lumen] (R-HSA-8956763)	0.556	3
UniProt:Q96AN5 TM143			0.556	3
UniProt:Q9UNK0 STX8			0.556	3
UniProt:Q96IV6 FXDC2			0.556	3
UniProt:Q5BJH2-2 TMEM128			0.556	3
UniProt:Q6ZSS7 MFSD6			0.556	3
UniProt:P21964 COMT	2	COMT [plasma membrane] (R-HSA-379386) COMT [cytosol] (R-HSA-175974)	0.556	3
UniProt:Q8NBD8 T229B			0.556	3
UniProt:Q8N2U9 S66A2			0.556	3
UniProt:Q8N2M4 TM86A			0.556	3
UniProt:Q6UX34 SNORC			0.556	3
UniProt:Q9Y6X1 SERP1	2	SERP1 [endoplasmic reticulum membrane] (R-HSA-381045) SERP1 [cytosol] (R-HSA-5250574)	0.556	3
UniProt:Q86W74-2 ANKRD46			0.556	3
UniProt:Q9NZG7 NINJ2			0.556	3
UniProt:A0A0C4DFN3 A0A0C4DFN3			0.556	3
UniProt:Q99519 NEU1	8	NEU1 W23* [lysosomal lumen] (R-HSA-5674155) NEU1 W29* [lysosomal lumen] (R-HSA-5674174) NEU1 E377* [lysosomal lumen] (R-HSA-5674181) NEU1 R225P [lysosomal lumen] (R-HSA-5674167) NEU1 L303P [lysosomal lumen] (R-HSA-5674182) NEU1 [extracellular region] (R-HSA-6806158) NEU1 [specific granule lumen] (R-HSA-6806148) NEU1 [lysosomal lumen] (R-HSA-1605788)	0.556	3
UniProt:O60831 PRAF2			0.556	3
UniProt:Q14802-3 FXYD3			0.556	3
UniProt:Q9BV81 EMC6			0.556	3
UniProt:P11836 CD20			0.556	3
UniProt:Q9Y225-2 RNF24			0.556	3
UniProt:Q6PI78 TMM65			0.556	3
UniProt:Q9Y666-2 SLC12A7			0.556	3
UniProt:Q9NZ42 PSENEN	2	PSENEN [endosome membrane] (R-HSA-9010101) PSENEN [plasma membrane] (R-HSA-157331)	0.556	3
UniProt:O75379 VAMP4	4	VAMP4 [transport vesicle] (R-HSA-6811023) VAMP4 [trans-Golgi network membrane] (R-HSA-6811021) VAMP4 [plasma membrane] (R-HSA-8864461) VAMP4 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869133)	0.556	3
UniProt:Q9UBY5 LPAR3	1	LPAR3 [plasma membrane] (R-HSA-419379)	0.556	3
UniProt:Q8WW34-2 TMEM239			0.556	3
UniProt:O14653 GOSR2	4	GOSR2 [endoplasmic reticulum membrane] (R-HSA-5689451) GOSR2 [ER to Golgi transport vesicle membrane] (R-HSA-5689800) GOSR2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-535472) GOSR2 [Golgi membrane] (R-HSA-6807755)	0.556	3
UniProt:P54315 PNLIPRP1	1	PNLIPRP1 [extracellular region] (R-HSA-3902876)	0.556	3
UniProt:Q5TGU0 TSPO2			0.556	3
UniProt:P49768-2 PSEN1			0.556	3
UniProt:Q8N6R1 SERP2			0.556	3
UniProt:Q9BUN8 DERL1	1	DERL1 [endoplasmic reticulum membrane] (R-HSA-6781898)	0.556	3
UniProt:Q969S6 TM203			0.556	3
UniProt:Q9UKR5 ERG28			0.556	3
UniProt:Q8WWP7 GIMA1			0.556	3
UniProt:Q96DZ9-2 CMTM5			0.556	3
UniProt:Q96EC8 YIPF6	2	YIPF6 [Golgi membrane] (R-HSA-434346) YIPF6 [cytoplasmic vesicle membrane] (R-HSA-434199)	0.556	3
UniProt:Q9NTJ5 SACM1L	2	SACM1L [endoplasmic reticulum membrane] (R-HSA-1604637) SACM1L [Golgi membrane] (R-HSA-1806242)	0.556	3
UniProt:Q9NWH2 TM242			0.556	3
UniProt:P16278 GLB1	8	GLB1 W509C [lysosomal lumen] (R-HSA-2262732) GLB1 Y83C [lysosomal lumen] (R-HSA-2262735) GLB1 R482C [lysosomal lumen] (R-HSA-2262739) GLB1 W273L [lysosomal lumen] (R-HSA-2262738) GLB1 [ficolin-1-rich granule lumen] (R-HSA-6800968) GLB1 [lysosomal lumen] (R-HSA-1605623) GLB1 [azurophil granule lumen] (R-HSA-6799124) GLB1 [extracellular region] (R-HSA-6806213)	0.556	3
UniProt:Q14318 FKBP8	2	PolyUb-FKBP8 [mitochondrial outer membrane] (R-HSA-6783001) FKBP8 [mitochondrial outer membrane] (R-HSA-5696928)	0.556	3
UniProt:Q9H2H9 SLC38A1	1	SLC38A1 [plasma membrane] (R-HSA-212663)	0.556	3
UniProt:P00387 CYB5R3	3	MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (R-HSA-198771) CYB5R3(27-301) [extracellular region] (R-HSA-6806205) CYB5R3(27-301) [azurophil granule lumen] (R-HSA-6799217)	0.556	3
UniProt:Q9UHE5 NAT8	1	NAT8 [endoplasmic reticulum membrane] (R-HSA-5692986)	0.556	3
UniProt:O14523 C2C2L			0.556	3
UniProt:Q6ZUI0 TPRG1			0.556	3
UniProt:P48449 LSS	1	LSS [endoplasmic reticulum membrane] (R-HSA-191371)	0.556	3
UniProt:P02724 GYPA	1	GYPA [plasma membrane] (R-HSA-8867204)	0.556	3
UniProt:Q8TAC9 SCAM5			0.556	3
UniProt:A0PK00 T120B			0.556	3
UniProt:P13236 CCL4	1	CCL4(24-92) [extracellular region] (R-HSA-443976)	0.556	3
UniProt:Q8WY98 TM234			0.556	3
UniProt:Q9BUP3-3 HTATIP2			0.556	3
UniProt:Q96FB2 Q96FB2			0.556	3
UniProt:Q8TBE7 S35G2			0.556	3
UniProt:Q03518 TAP1	3	TAP1 [phagocytic vesicle membrane] (R-HSA-1236845) TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-8863953) TAP1 [endoplasmic reticulum membrane] (R-HSA-947474)	0.556	3
UniProt:Q9P0B6 CC167			0.556	3
UniProt:Q9HD20-3 ATP13A1			0.556	3
UniProt:P60201-2 PLP1			0.556	3
UniProt:Q8NHS1 CLDN2			0.556	3
UniProt:Q9Y3E0 GOT1B			0.556	3
UniProt:P11215 ITGAM	3	ITGAM [specific granule membrane] (R-HSA-6799647) ITGAM [tertiary granule membrane] (R-HSA-6800979) ITGAM [plasma membrane] (R-HSA-202757)	0.556	3
UniProt:O95406 CNIH1	3	CNIH1 [endoplasmic reticulum membrane] (R-HSA-5689439) CNIH1 [ER to Golgi transport vesicle membrane] (R-HSA-5689776) CNIH1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5689778)	0.556	3
UniProt:P56557 TM50B			0.556	3
UniProt:Q53HI1 UNC50			0.556	3
UniProt:Q9BWH2 FUND2			0.556	3
UniProt:Q9Y5Y5 PEX16	2	PEX16 [peroxisomal membrane] (R-HSA-9603805) PEX16 [cytosol] (R-HSA-9603790)	0.556	3
UniProt:Q9NQQ7-3 Q9NQQ73			0.556	3
UniProt:Q8N4L2 PP4P2			0.556	3
UniProt:Q9Y342 PLLP			0.556	3
UniProt:Q9BRI3 SLC30A2	2	SLC30A2 [endosome membrane] (R-HSA-435363) SLC30A2 [synaptic vesicle membrane] (R-HSA-4084714)	0.556	3
UniProt:Q8WVV5 BTN2A2	1	BTN2A2 [plasma membrane] (R-HSA-8851047)	0.556	3
UniProt:P24593 IGFBP5	5	IGFBP5 [endoplasmic reticulum lumen] (R-HSA-8956738) p-IGFBP5 [endoplasmic reticulum lumen] (R-HSA-8956988) IGFBP5 [extracellular region] (R-HSA-381414) IGFBP5(21-163) [extracellular region] (R-HSA-381415) IGFBP5(164-272) [extracellular region] (R-HSA-381478)	0.556	3
UniProt:Q5QGT7 RTP2	2	RTP2 [endoplasmic reticulum membrane] (R-HSA-9752982) RTP2 [plasma membrane] (R-HSA-8939446)	0.556	3
UniProt:Q9H2C2 ARV1	1	ARV1 [endoplasmic reticulum membrane] (R-HSA-5216144)	0.556	3
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.556	3
UniProt:P17152 TMEM11	1	TMEM11 [mitochondrial inner membrane] (R-HSA-8949578)	0.556	3
UniProt:O00767 SCD	1	SCD [endoplasmic reticulum membrane] (R-HSA-400117)	0.556	3
UniProt:P04921 GYPC	1	GYPC [plasma membrane] (R-HSA-420422)	0.556	3
UniProt:Q9BWQ6 YIPF2			0.556	3
IntAct:EBI-23683896 CCSB ORF ID			0.556	3
UniProt:Q9NYZ1 TV23B			0.556	3
UniProt:Q7L5A8 FA2H	1	FA2H [endoplasmic reticulum membrane] (R-HSA-5693771)	0.556	3
UniProt:Q9P0S3 ORMDL1	1	ORMDL1 [endoplasmic reticulum membrane] (R-HSA-8865584)	0.556	3
UniProt:O43169 CYB5B	2	CYB5B [endoplasmic reticulum membrane] (R-HSA-9842695) CYB5B [mitochondrial outer membrane] (R-HSA-8943390)	0.556	3
UniProt:Q9NSU2-1 TREX1			0.556	3
UniProt:Q01740 FMO1	1	FMO1 [endoplasmic reticulum lumen] (R-HSA-217270)	0.556	3
UniProt:Q9ULC5 ACSL5	1	ACSL5 [endoplasmic reticulum membrane] (R-HSA-165011)	0.556	3
IntAct:EBI-23343277 CCSB ORF ID			0.556	3
UniProt:Q8NG98 OR7D4	2	OR7D4 [endoplasmic reticulum membrane] (R-HSA-9751364) OR7D4 [plasma membrane] (R-HSA-446823)	0.556	3
UniProt:Q9P0S9 TM14C			0.556	3

Cite Us!