NACT co-transports trivalent citrate and a sodium ion

Stable Identifier
R-HSA-433104
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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NACT co-transports trivalent citrate and a sodium ion
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The human SLC13A5 gene encodes a sodium-coupled citrate transporter, NACT. This gene is expressed mainly in the liver, with lower levels in brain and testis. NACT has a preference for trivalent citrate (Inoue K et al, 2002).
Literature References
PubMed ID Title Journal Year
12445824 Human Na+ -coupled citrate transporter: primary structure, genomic organization, and transport function

Zhuang, L, Ganapathy, V, Inoue, K

Biochem Biophys Res Commun 2002
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as an event of
Catalyst Activity

citrate transmembrane transporter activity of SLC13A5 [plasma membrane]

Physical Entity
SLC13A5 [plasma membrane] (Homo sapiens)
Activity
citrate transmembrane transporter activity (GO:0015137)
Orthologous Events
NACT co-transports trivalent citrate and a sodium ion (Bos taurus)
NACT co-transports trivalent citrate and a sodium ion (Caenorhabditis elegans)
NACT co-transports trivalent citrate and a sodium ion (Canis familiaris)
NACT co-transports trivalent citrate and a sodium ion (Drosophila melanogaster)
NACT co-transports trivalent citrate and a sodium ion (Gallus gallus)
NACT co-transports trivalent citrate and a sodium ion (Mus musculus)
NACT co-transports trivalent citrate and a sodium ion (Rattus norvegicus)
NACT co-transports trivalent citrate and a sodium ion (Sus scrofa)
NACT co-transports trivalent citrate and a sodium ion (Xenopus tropicalis)
Authored
Jassal, B  (2009-08-21)
Reviewed
He, L  (2009-11-12)
Created
Jassal, B  (2009-08-21)
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