NEDD8-K556,K567-TGFBR2 [plasma membrane]

Stable Identifier
R-HSA-4332222
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
NEDD8-K556,K567-TGFBR2 [plasma membrane] icon
Locations in the PathwayBrowser for interactor UniProt:P54252 ATXN3
External Reference Information
External Reference
Gene Names
TGFBR2
Chain
signal peptide:1-22, chain:23-567
Other Identifiers
11724682_s_at
11750840_s_at
16938562
1814_at
1815_g_at
207334_PM_s_at
207334_s_at
208944_PM_at
208944_at
2615378
2615379
2615380
2615384
2615393
2615395
2615396
2615401
2615402
2615403
2615410
2615412
2615413
2615414
2615415
2615423
7048
8078350
A_14_P126005
A_23_P211957
D50683_at
GE57247
GE578892
GO:0000166
GO:0001568
GO:0001569
GO:0001570
GO:0001701
GO:0001837
GO:0001947
GO:0002053
GO:0002088
GO:0002376
GO:0002651
GO:0002663
GO:0002666
GO:0003148
GO:0003149
GO:0003151
GO:0003180
GO:0003181
GO:0003186
GO:0003214
GO:0003274
GO:0003417
GO:0003430
GO:0003824
GO:0004672
GO:0004674
GO:0004675
GO:0005024
GO:0005026
GO:0005515
GO:0005524
GO:0005539
GO:0005576
GO:0005829
GO:0005886
GO:0005901
GO:0006468
GO:0006915
GO:0007155
GO:0007178
GO:0007179
GO:0007219
GO:0007224
GO:0007369
GO:0007420
GO:0007507
GO:0008284
GO:0009410
GO:0009893
GO:0009897
GO:0010468
GO:0010634
GO:0010718
GO:0012501
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0017002
GO:0019209
GO:0023052
GO:0030154
GO:0030324
GO:0032147
GO:0032924
GO:0034713
GO:0034714
GO:0035162
GO:0035909
GO:0036211
GO:0038023
GO:0042127
GO:0043011
GO:0043235
GO:0045121
GO:0045766
GO:0046332
GO:0046872
GO:0048185
GO:0048701
GO:0048844
GO:0048856
GO:0048870
GO:0050431
GO:0051138
GO:0051216
GO:0051239
GO:0060021
GO:0060089
GO:0060090
GO:0060391
GO:0060395
GO:0060412
GO:0060425
GO:0060433
GO:0060434
GO:0060439
GO:0060440
GO:0060443
GO:0060463
GO:0061520
GO:0062009
GO:0070021
GO:0070723
GO:0071363
GO:0072091
GO:0098772
GO:0140096
GO:0141091
GO:1905007
GO:1905317
GO:1990086
GO:1990428
GO:2000379
GO:2000563
GO:2000736
HMNXSV003024864
ILMN_1726245
ILMN_1744862
ILMN_2384241
PH_hs_0004687
TC03000149.hg
TC03002268.hg
g1827474_3p_at
g4507468_3p_a_at
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
neddylated lysine (monoNEDD8 [cytosol]) at 556
Coordinate
556
Modification
monoNEDD8 [cytosol]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a nedd8 protein.
Name
neddylated lysine (monoNEDD8 [cytosol]) at 567
Coordinate
567
Modification
monoNEDD8 [cytosol]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a nedd8 protein.
Cross References
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
ZINC - Investigational
GeneCards
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
Interactors (94)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P01137 TGFB1  7 0.886 11
 UniProt:P10600 TGFB3  3 0.765 8
 UniProt:Q9H992 MARH7      0.643 5
 UniProt:Q8IX30 SCUBE3  3 0.632 6
 UniProt:P09471 GNAO1  1 0.556 3
 UniProt:Q99435-2 NELL2      0.556 3
 UniProt:Q969W3 VCF1      0.556 3
 UniProt:Q3SY56 SP6      0.556 3
 UniProt:Q8NCS7 SLC44A5  1 0.556 3
 UniProt:Q96BQ3 TRI43      0.556 3
 UniProt:O14531 DPYSL4  3 0.556 3
 UniProt:P48730-2 CSNK1D      0.556 3
 UniProt:Q9UMR2 DD19B      0.556 3
 UniProt:Q9UHP3 USP25  1 0.556 3
 UniProt:P46977 STT3A  1 0.556 3
 UniProt:P06756 ITGAV  3 0.556 3
 UniProt:Q8TAB5 CA216      0.556 3
 UniProt:P49184 DNASE1L1  2 0.556 3
 UniProt:Q6NTF9-3 Q6NTF93      0.556 3
 UniProt:Q96NA2 RILP  1 0.556 3
 UniProt:P26378-2 P263782      0.556 3
 UniProt:Q9BZ95-3 Q9BZ953      0.556 3
 UniProt:Q93084-2 Q930842      0.556 3
 UniProt:P61966-2 AP1S1      0.556 3
 UniProt:Q8NE08 Q8NE08      0.556 3
 UniProt:Q4VBR4 Q4VBR4      0.556 3
 UniProt:P61513 RPL37A  1 0.556 3
 UniProt:Q16560-2 SNRNP35      0.556 3
 UniProt:O75874 IDH1  10 0.556 3
 UniProt:P19544-6 WT1      0.556 3
 UniProt:Q6PI98 INO80C  1 0.556 3
 UniProt:Q8TBE0 BAHD1      0.556 3
 UniProt:P23276 KEL  1 0.556 3
 UniProt:Q9NP61 ARFGAP3  1 0.556 3
 UniProt:Q8NC51 SERB1      0.556 3
 UniProt:Q8TAT6 NPLOC4  2 0.556 3
 UniProt:Q9Y228 T3JAM      0.556 3
 UniProt:O75143-2 O751432      0.556 3
 UniProt:Q14728 MFS10      0.556 3
 UniProt:P54253 ATX1      0.556 3
 UniProt:Q9ULR0 ISY1  1 0.556 3
 UniProt:Q96IY1 NSL1  1 0.556 3
 UniProt:Q16549 PCSK7      0.556 3
 UniProt:Q99720-4 SIGMAR1      0.556 3
 UniProt:Q16586 SGCA      0.556 3
 UniProt:P40227 CCT6A  1 0.556 3
 IntAct:EBI-25836632 CCSB      0.556 3
 UniProt:Q7Z614-3 SNX20      0.556 3
 UniProt:Q13428-5 TCOF1      0.556 3
 UniProt:Q13702-2 Q137022      0.556 3
 UniProt:Q8TBJ4 PLPPR1  1 0.556 3
 IntAct:EBI-25833683 CCSB      0.556 3
 UniProt:P51674 GPM6A      0.556 3
 UniProt:Q9NPC7 MYNN      0.556 3
 UniProt:Q8N448 LNX2      0.556 3
 UniProt:Q07869 PPARA  2 0.556 3
 UniProt:O60259 KLK8  3 0.556 3
 UniProt:P54252 ATXN3  2 0.556 3
 UniProt:P52756 RBM5  1 0.556 3
 UniProt:P54819 AK2  1 0.556 3
 UniProt:Q9NUD9 PIGV  1 0.556 3
 UniProt:O43463 SUV39H1  1 0.556 3
 UniProt:P21246 PTN  1 0.556 3
 UniProt:Q7Z434 MAVS  2 0.556 3
 UniProt:Q96E93 KLRG1  1 0.556 3
 UniProt:Q13200 PSMD2  5 0.556 3
 UniProt:P15036 ETS2  2 0.556 3
 UniProt:P25490 YY1  1 0.556 3
 UniProt:P42858 HTT  1 0.556 3
 UniProt:P12830 CDH1  8 0.556 3
 UniProt:P01106 MYC  2 0.556 3
 UniProt:P36894 BMPR1A  2 0.527 4
 UniProt:P42338 PIK3CB  1 0.527 3
 UniProt:Q96S97 MYADM      0.527 4
 UniProt:O00459 PIK3R2  3 0.527 3
 UniProt:Q7Z4F1 LRP10  1 0.527 3
 UniProt:Q92569 PIK3R3  2 0.527 3
 UniProt:Q9NZ56 FMN2      0.527 3
 UniProt:Q8IWF6 DENND6A  1 0.527 3
 UniProt:Q13705 ACVR2B  1 0.527 3
 UniProt:Q9NRW1 RAB6B  6 0.527 2
 UniProt:P55082 MFAP3  1 0.527 2
 UniProt:Q969Z4 TR19L      0.527 2
 UniProt:Q6P5Z2 PKN3  2 0.527 3
 UniProt:Q99741 CDC6  4 0.527 2
 UniProt:Q16513 PKN2  2 0.527 3
 UniProt:Q6PJF5 RHBDF2  2 0.527 2
 UniProt:P04626 ERBB2  20 0.527 3
 UniProt:P23458 JAK1  6 0.527 3
 UniProt:P07200  7 0.525 2
 UniProt:Q93074 MED12  1 0.524 3
 UniProt:Q9UER7 DAXX  13 0.508 2
 UniProt:A2AGH6 Med12  2 0.471 3
 UniProt:Q9BYF1 ACE2  5 0.463 2
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