Reactome | PUM1 [cytosol]

PUM1 [cytosol]

Stable Identifier

R-HSA-434211

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Pumilio homolog 1, PUM1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P06427 VE6

Expand all

External Reference Information

External Reference

UniProt:Q14671 PUM1

Gene Names

PUM1, KIAA0099, PUMH1

Chain

initiator methionine:, chain:2-1186

Reference Genes

BioGPS Gene:9698 PUM1

COSMIC (genes):PUM1 PUM1

CTD Gene:9698 PUM1

dbSNP Gene:9698 PUM1

ENSEMBL:ENSG00000134644 PUM1

HGNC:14957 PUM1

KEGG:hsa:9698 PUM1

Monarch:9698 PUM1

NCBI Gene:9698 PUM1

OMIM:607204 PUM1

UCSC:Q14671 PUM1

Reference Transcript

Other Identifiers

11716473_at

11716474_a_at

16684344

16684385

16684387

201164_PM_s_at

201164_s_at

201165_PM_s_at

201165_s_at

201166_PM_s_at

201166_s_at

2404255

2404256

2404259

2404260

2404263

2404264

2404265

2404267

2404268

2404269

2404270

2404271

2404272

2404275

2404276

2404277

2404278

2404279

2404280

2404281

2404282

2404284

2404285

2404286

2404289

2404290

2404291

2404295

2404298

2404299

2404304

2404305

2404312

2404313

2404315

2404316

2404317

2404318

2404319

40048_at

7914296

7914322

7914324

9698

A_23_P10815

A_23_P170820

A_24_P171345

D43951_at

GE57220

GO:0000932

GO:0003723

GO:0003730

GO:0005515

GO:0005654

GO:0005737

GO:0005829

GO:0006417

GO:0007283

GO:0008344

GO:0010494

GO:0010608

GO:0016441

GO:0022414

GO:0030154

GO:0030424

GO:0035196

GO:0035198

GO:0043226

GO:0043488

GO:0048863

GO:0051726

GO:0051983

GO:0060964

GO:0061157

GO:0061158

GO:1900246

GO:2000637

HMNXSV003028335

HMNXSV003041126

Hs.153834.0.S1_3p_a_at

Hs.153834.0.S2_3p_a_at

ILMN_1783424

ILMN_2401155

PH_hs_0009253

PH_hs_0040230

RNA33594|snoRNA_scaRNA_190_91

TC01002445.hg

TC01002446.hg

TC01002447.hg

g13491165_3p_a_at

Participates

as a component of

Golgi-associated vesicle interacting proteins [cytosol] (Homo sapiens)

as an input of

Recruitment Of Cytoplasmic Proteins To Vesicles (Homo sapiens)

Inferred To

pum1 [cytosol] (Xenopus tropicalis)

Pum1 [cytosol] (Mus musculus)

Pum1 [cytosol] (Rattus norvegicus)

puf-9 [cytosol] (Caenorhabditis elegans)

puf-3 [cytosol] (Caenorhabditis elegans)

puf-5 [cytosol] (Caenorhabditis elegans)

pum [cytosol] (Drosophila melanogaster)

fbf-2 [cytosol] (Caenorhabditis elegans)

PUM1 [cytosol] (Bos taurus)

PUM1 [cytosol] (Canis familiaris)

PUM1 [cytosol] (Gallus gallus)

PUM1 [cytosol] (Sus scrofa)

fbf-1 [cytosol] (Caenorhabditis elegans)

puf-11 [cytosol] (Caenorhabditis elegans)

puf-6 [cytosol] (Caenorhabditis elegans)

puf-8 [cytosol] (Caenorhabditis elegans)

puf-7 [cytosol] (Caenorhabditis elegans)

Homologues of PUM1 [cytosol] (Caenorhabditis elegans)

Cross References

OpenTargets

ENSG00000134644

ENSEMBL

ENSP00000362847, ENSP00000257075, ENSG00000134644, ENST00000373742, ENST00000257075, ENSP00000391723, ENST00000440538, ENST00000426105, ENSP00000401777

HPA

ENSG00000134644-PUM1

GeneCards

PUM1

PRO

Q14671

Pharos - Targets

Q14671

GlyGen

Q14671

PDB

5YKH, 5YKI, 1IB2, 3Q0L, 3Q0O, 3BSX, 3Q0N, 3Q0M, 3Q0P, 3BSB, 2YJY, 1M8Y, 1M8W, 1M8Z, 1M8X

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.671	5
UniProt:O15354 GPR37	1	GPR37 [plasma membrane] (R-HSA-5333623)	0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P28799-2 GRN			0.556	3
UniProt:P28799 GRN	2	GRN [azurophil granule lumen] (R-HSA-6799168) GRN [extracellular region] (R-HSA-6806217)	0.556	3
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.539	5
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.528	5
UniProt:Q96PV0 SYNGAP1	1	SYNGAP1 [cytosol] (R-HSA-5658217)	0.527	2
UniProt:P06427 VE6			0.488	2
UniProt:Q84291 VE6			0.488	2
UniProt:P06929 VE6			0.488	2
UniProt:P31947 SFN	1	SFN [cytosol] (R-HSA-1445105)	0.471	4