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PICALM [Golgi membrane]
Stable Identifier
R-HSA-434341
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
Phosphatidylinositol-binding clathrin assembly protein, PICAL_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
trans-Golgi Network Vesicle Budding (Homo sapiens)
Golgi Associated Vesicle Biogenesis (Homo sapiens)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture (Homo sapiens)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
PICALM [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
PICALM [Golgi membrane] (Homo sapiens)
trans-Golgi Network Coat Assembly (Homo sapiens)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
PICALM [Golgi membrane] (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
PICALM [Golgi membrane] (Homo sapiens)
trans-Golgi Network Vesicle Scission (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
PICALM [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13492 PICALM
Gene Names
PICALM, CALM
Chain
initiator methionine:, chain:2-652
Reference Genes
BioGPS Gene:8301 PICALM
COSMIC (genes):PICALM PICALM
CTD Gene:8301 PICALM
dbSNP Gene:8301 PICALM
ENSEMBL:ENSG00000073921 PICALM
ENSEMBL_homo_sapiens_GENE:ENSG00000073921.18 PICALM
HGNC:15514 PICALM
KEGG Gene (Homo sapiens):8301 PICALM
Monarch:8301 PICALM
NCBI Gene:8301 PICALM
OMIM:603025 PICALM
UCSC:Q13492 PICALM
Reference Transcript
RefSeq:NM_001008660.2 PICALM
RefSeq:NM_007166.3 PICALM
RefSeq:XM_005274331.2 PICALM
RefSeq:NM_001206946.1 PICALM
RefSeq:NM_001206947.1 PICALM
Other Identifiers
11719909_s_at
11719910_a_at
11747548_a_at
11747549_x_at
11748665_a_at
11755506_a_at
11755507_x_at
16743017
212506_PM_at
212506_at
212511_PM_at
212511_at
215236_PM_s_at
215236_s_at
215832_PM_x_at
3385176
3385177
3385178
3385179
3385180
3385181
3385182
3385194
3385198
3385203
3385204
3385205
3385208
3385211
3385215
3385216
3385217
3385218
3385223
3385228
3385229
3385231
3385234
3385236
3385238
3385251
3385252
3385253
3385254
3385255
3385256
37685_at
73192_at
78074_i_at
78076_r_at
7950838
8301
A_23_P203658
A_33_P3382157
GE59183
GO:0000149
GO:0001540
GO:0005515
GO:0005543
GO:0005545
GO:0005546
GO:0005634
GO:0005768
GO:0005769
GO:0005794
GO:0005829
GO:0005886
GO:0005905
GO:0006351
GO:0006355
GO:0006879
GO:0006897
GO:0006898
GO:0006900
GO:0007409
GO:0007611
GO:0008021
GO:0008092
GO:0008289
GO:0009986
GO:0010629
GO:0016020
GO:0016185
GO:0016188
GO:0016192
GO:0016197
GO:0030097
GO:0030100
GO:0030132
GO:0030136
GO:0030154
GO:0030276
GO:0031267
GO:0031410
GO:0031623
GO:0031982
GO:0032050
GO:0032880
GO:0035459
GO:0042734
GO:0043025
GO:0043226
GO:0043231
GO:0043547
GO:0045211
GO:0045296
GO:0045334
GO:0045893
GO:0048156
GO:0048261
GO:0048268
GO:0048471
GO:0048813
GO:0048856
GO:0050750
GO:0050877
GO:0055065
GO:0060586
GO:0061024
GO:0065003
GO:0070381
GO:0072583
GO:0072659
GO:0097418
GO:0097494
GO:0097753
GO:0098894
GO:0150093
GO:1902004
GO:1902959
GO:1902961
GO:1902963
GO:1903077
GO:2000009
HMNXSV003051276
Hs.7885.1.S1_3p_at
Hs.7885.1.S2_3p_at
Hs.7885.2.S1_3p_x_at
Hs.7885.3.S1_3p_s_at
ILMN_1715273
ILMN_1778709
PH_hs_0022107
TC11002165.hg
U45976_at
Participates
as a candidate of
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
Other forms of this molecule
PICALM [cytosol]
PICALM [cytoplasmic vesicle membrane]
Inferred To
clmA [Golgi membrane]
(Dictyostelium discoideum)
PICALM [Golgi membrane]
(Bos taurus)
PICALM [Golgi membrane]
(Canis familiaris)
PICALM [Golgi membrane]
(Gallus gallus)
PICALM [Golgi membrane]
(Sus scrofa)
lap [Golgi membrane]
(Drosophila melanogaster)
YAP1802 [Golgi membrane]
(Saccharomyces cerevisiae)
unc-11 [Golgi membrane]
(Caenorhabditis elegans)
Homologues of PICALM [Golgi membrane]
(Saccharomyces cerevisiae)
Picalm [Golgi membrane]
(Mus musculus)
Picalm [Golgi membrane]
(Rattus norvegicus)
YAP1801 [Golgi membrane]
(Saccharomyces cerevisiae)
Cross References
RefSeq
NP_001193876.1
,
XP_005274388.1
,
NP_009097.2
,
NP_001008660.1
,
NP_001193875.1
OpenTargets
ENSG00000073921
HPA
ENSG00000073921-PICALM
GeneCards
Q13492
Ensembl
ENST00000526033
,
ENSG00000073921
,
ENSP00000377015
,
ENSP00000433846
,
ENST00000528398
,
ENST00000356360
,
ENSP00000436958
,
ENST00000393346
,
ENST00000532317
,
ENSP00000434884
,
ENSP00000348718
PRO
Q13492
Pharos - Targets
Q13492
Orphanet
22520
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q14192 FHL2
1
FHL2 [nucleoplasm]
(R-HSA-561161)
0.645
8
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.615
8
UniProt:P42566 EPS15
2
p-Y849 EPS15 [cytosol]
(R-HSA-8867028)
EPS15 [cytosol]
(R-HSA-182920)
0.59
2
UniProt:Q9NYZ3 GTSE1
4
GTSE1 [cytosol]
(R-HSA-8852264)
p-S435-GTSE1 [cytosol]
(R-HSA-8852316)
p-S435-GTSE1 [nucleoplasm]
(R-HSA-8852332)
p-T513,T526-GTSE1 [cytosol]
(R-HSA-8852308)
0.527
2
UniProt:O00443 PIK3C2A
3
PIK3C2A [Golgi membrane]
(R-HSA-432679)
PIK3C2A [cytosol]
(R-HSA-1604624)
PIK3C2A [cytoplasmic vesicle membrane]
(R-HSA-432683)
0.527
2
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