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SLC30A5 [secretory granule membrane]
Stable Identifier
R-HSA-437105
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
secretory granule membrane
Synonyms
ZnT5, Zinc transporter 5, ZNT5_HUMAN
Locations in the PathwayBrowser for interactor UniProt:P27930 IL1R2
Expand all
Metabolism of proteins (Homo sapiens)
Peptide hormone metabolism (Homo sapiens)
Insulin processing (Homo sapiens)
ZnT5 transports zinc into secretory granules in pancreatic beta cells (Homo sapiens)
SLC30A5 [secretory granule membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Metal ion SLC transporters (Homo sapiens)
Zinc transporters (Homo sapiens)
Zinc efflux and compartmentalization by the SLC30 family (Homo sapiens)
ZnT5 transports zinc into secretory granules in pancreatic beta cells (Homo sapiens)
SLC30A5 [secretory granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8TAD4 SLC30A5
Gene Names
SLC30A5, ZNT5, ZNTL1, ZTL1, UNQ863/PRO1879
Chain
chain:1-765
Reference Genes
BioGPS Gene:64924 SLC30A5
COSMIC (genes):SLC30A5 SLC30A5
CTD Gene:64924 SLC30A5
dbSNP Gene:64924 SLC30A5
ENSEMBL:ENSG00000145740 SLC30A5
ENSEMBL_homo_sapiens_GENE:ENSG00000145740.20 SLC30A5
HGNC:19089 SLC30A5
KEGG Gene (Homo sapiens):64924 SLC30A5
Monarch:64924 SLC30A5
NCBI Gene:64924 SLC30A5
OMIM:607819 SLC30A5
UCSC:Q8TAD4 SLC30A5
Reference Transcript
RefSeq:NM_001251969.1 SLC30A5
RefSeq:NM_024055.4 SLC30A5
RefSeq:NM_022902.4 SLC30A5
Other Identifiers
11731851_x_at
11732282_a_at
11732283_x_at
11744973_a_at
11747225_x_at
11759084_a_at
1555334_3p_s_at
1555334_PM_s_at
1555334_s_at
16985572
218989_PM_x_at
218989_x_at
220181_PM_x_at
220181_x_at
232432_PM_s_at
232432_s_at
243166_PM_at
243166_at
2813365
2813366
2813367
2813371
2813373
2813375
2813376
2813377
2813378
2813379
2813381
2813382
2813383
2813384
2813385
2813386
2813387
2813388
2813389
2813390
2813391
2813394
2813395
2813397
2813398
2813401
2813402
2813403
2813404
2813405
2813407
59029_at
64924
65193_at
66873_at
8105801
91769_at
A_14_P108551
A_14_P130102
A_23_P160103
A_23_P218988
A_24_P257585
A_24_P37946
A_33_P3384988
GE82778
GE87008
GO:0000139
GO:0005215
GO:0005385
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006506
GO:0006629
GO:0006811
GO:0006812
GO:0006824
GO:0006829
GO:0006882
GO:0008324
GO:0012507
GO:0015297
GO:0016020
GO:0016324
GO:0030070
GO:0030141
GO:0030658
GO:0030667
GO:0031410
GO:0032580
GO:0032588
GO:0036211
GO:0043226
GO:0046872
GO:0051604
GO:0055065
GO:0055085
GO:0062111
GO:0071577
GO:0140826
GO:1901135
GO:1904257
GO:1990674
HMNXSV003020587
HMNXSV003037282
HMNXSV003038906
Hs.129445.2.S1_3p_a_at
Hs.165490.0.A1_3p_at
Hs2Affx.1.207.S1_3p_s_at
ILMN_1664153
ILMN_1709728
ILMN_1732079
ILMN_2258471
PH_hs_0020783
TC05000296.hg
g13443011_3p_at
g13443011_3p_x_at
Other forms of this molecule
SLC30A5 [Golgi membrane]
Inferred To
Slc30a5 [secretory granule membrane]
(Rattus norvegicus)
SLC30A5 [secretory granule membrane]
(Bos taurus)
SLC30A5 [secretory granule membrane]
(Canis familiaris)
SLC30A5 [secretory granule membrane]
(Danio rerio)
SLC30A5 [secretory granule membrane]
(Dictyostelium discoideum)
SLC30A5 [secretory granule membrane]
(Gallus gallus)
SLC30A5 [secretory granule membrane]
(Mus musculus)
SLC30A5 [secretory granule membrane]
(Sus scrofa)
SLC30A5 [secretory granule membrane]
(Xenopus tropicalis)
slc-30a5 [secretory granule membrane]
(Caenorhabditis elegans)
MSC2 [secretory granule membrane]
(Saccharomyces cerevisiae)
cis4 [secretory granule membrane]
(Schizosaccharomyces pombe)
Homologues of SLC30A5 [secretory granule membrane]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_001238898.1
,
NP_076960.1
,
NP_075053.2
Guide to Pharmacology - Targets
1125
OpenTargets
ENSG00000145740
HPA
ENSG00000145740-SLC30A5
GeneCards
Q8TAD4
Ensembl
ENSP00000370241
,
ENSP00000421251
,
ENSG00000145740
,
ENST00000502979
,
ENST00000396591
,
ENSP00000379836
,
ENST00000380860
PRO
Q8TAD4
Pharos - Targets
Q8TAD4
HMDB Protein
HMDBP10922
Interactors (17)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q6NXT4 ZNT6
0.791
14
UniProt:Q9H8X2 IPPK
2
IPPK [cytosol]
(R-HSA-1604598)
IPPK [nucleoplasm]
(R-HSA-2023949)
0.527
2
UniProt:Q9Y2A9 B3GNT3
1
B3GNT3 [Golgi membrane]
(R-HSA-916819)
0.527
2
UniProt:Q8WUJ1 NEUFC
0.527
2
UniProt:P25090 FPR2
4
FPR2 [specific granule membrane]
(R-HSA-6803319)
FPR2 [ficolin-1-rich granule membrane]
(R-HSA-6803335)
FPR2 [tertiary granule membrane]
(R-HSA-6803296)
FPR2 [plasma membrane]
(R-HSA-416408)
0.527
3
UniProt:P16444 DPEP1
1
DPEP1 [plasma membrane]
(R-HSA-2142820)
0.527
2
UniProt:P27930 IL1R2
1
IL1R2 [plasma membrane]
(R-HSA-197598)
0.527
2
UniProt:P21217 FUT3
1
FUT3 [Golgi membrane]
(R-HSA-5693934)
0.527
2
UniProt:A2RUU4 COLL1
0.527
2
UniProt:P04201 MAS
0.527
2
UniProt:Q9UGM1 CHRNA9
1
CHRNA9 [plasma membrane]
(R-HSA-507827)
0.527
2
UniProt:P49755 TMED10
5
TMED10 [Golgi membrane]
(R-HSA-6808801)
TMED10 [transport vesicle]
(R-HSA-6808802)
TMED10 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5689845)
TMED10 [ER to Golgi transport vesicle membrane]
(R-HSA-5689843)
TMED10 [endoplasmic reticulum membrane]
(R-HSA-5689479)
0.527
2
UniProt:Q01151 CD83
0.527
2
UniProt:Q8TCT7 SPPL2B
1
SPPL2B [plasma membrane]
(R-HSA-8863116)
0.527
4
UniProt:Q9H8Y8 GORASP2
2
GORASP2 [Golgi membrane]
(R-HSA-2422385)
p-T222,T225-GORASP2 [Golgi membrane]
(R-HSA-2422965)
0.527
2
UniProt:Q8N6G5 CSGALNACT2
1
CSGALNACT2 [Golgi membrane]
(R-HSA-1971506)
0.527
3
UniProt:P32970 CD70
1
CD70 [plasma membrane]
(R-HSA-5667139)
0.527
2
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