NOTCH1 Coactivator Complex binds MYC promoter

Stable Identifier
R-HSA-4396371
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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NICD1, as a part of the NOTCH1 Coactivator Complex, binds to the MYC promoter (Palomero et al. 2006).
Literature References
PubMed ID Title Journal Year
17114293 NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

Sulis, ML, Look, AT, Palomero, T, Soulier, J, Ferrando, AA, Real, PJ, Neuberg, D, Lim, WK, Weng, AP, Sigaux, F, Margolin, A, Young, RA, O'Neil, J, Odom, DT, Aster, JC, Califano, A, Barnes, KC

Proc Natl Acad Sci U S A 2006
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