Reactome | NCOA3 [nucleoplasm]

NCOA3 [nucleoplasm]

Stable Identifier

R-HSA-442488

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Nuclear receptor coactivator 3, NCOA3_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Y6Q9 NCOA3

Gene Names

NCOA3, AIB1, BHLHE42, RAC3, TRAM1

Chain

initiator methionine:, chain:2-1424

Reference Genes

COSMIC (genes):NCOA3 NCOA3

COSMIC (genes):RAC3 NCOA3

COSMIC (genes):TRAM1 NCOA3

dbSNP Gene:8202 NCOA3

ENSEMBL:ENSG00000124151 NCOA3

Participates

as a member of

as a component of

as an input of

Other forms of this molecule

p-S857 NCOA3 [nucleoplasm]

Inferred To

Ncoa3 [nucleoplasm] (Mus musculus)

Ncoa3 [nucleoplasm] (Rattus norvegicus)

NCOA3 [nucleoplasm] (Bos taurus)

NCOA3 [nucleoplasm] (Canis familiaris)

NCOA3 [nucleoplasm] (Gallus gallus)

NCOA3 [nucleoplasm] (Sus scrofa)

ncoa3 [nucleoplasm] (Xenopus tropicalis)

tai [nucleoplasm] (Drosophila melanogaster)

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.688	4
UniProt:O43791 SPOP	1	SPOP [nucleoplasm] (R-HSA-5635035)	0.632	6
UniProt:Q86X55 CARM1	1	CARM1 [nucleoplasm] (R-HSA-400139)	0.623	13
UniProt:P61289 PSME3	1	PSME3 [cytosol] (R-HSA-68816)	0.602	5
UniProt:P28065 PSMB9	3	pro-PSMB9 [cytosol] (R-HSA-9908136) PSMB9 [cytosol] (R-HSA-68765) PSMB9(1-20) [cytosol] (R-HSA-9908132)	0.581	3
UniProt:P10276 RARA	3	RARA [nucleoplasm] (R-HSA-446164) polySUMO2-K166,K171,K399-RARA [nucleoplasm] (R-HSA-4341042) SUMO2-K166,177,399-p-S219,269-RARA [nucleoplasm] (R-HSA-5334830)	0.564	2
ChEBI:90954 MCB-613			0.558	2
UniProt:Q8VIM5-1 MYOCD			0.544	5
UniProt:Q09472 EP300	5	EP300 [nucleoplasm] (R-HSA-381325) p-S,T-EP300 [nucleoplasm] (R-HSA-8878072) FOXO4-S-S-EP300 [nucleoplasm] (R-HSA-9617691) Foxo4-S-S-EP300 [nucleoplasm] (R-HSA-9617720) monoSUMO1-K1020,1024-EP300 [nucleoplasm] (R-HSA-3899306)	0.536	2
UniProt:Q92793 CREBBP	4	CREBBP [nucleoplasm] (R-HSA-193545) CREBBP [cytosol] (R-HSA-9756493) FOXO4-S-S-CREBBP [nucleoplasm] (R-HSA-9617684) monoSUMO1-K998,K1033,K1056-CREBBP [nucleoplasm] (R-HSA-3927877)	0.527	12
UniProt:Q6PL18 ATAD2	1	ATAD2 [nucleoplasm] (R-HSA-8937250)	0.524	2
UniProt:P48281	2	polySUMO2-VDR [nucleoplasm] (R-MMU-4546376) VDR [nucleoplasm] (R-MMU-375512)	0.508	2
UniProt:P51157 RAB28			0.508	2
UniProt:P10275 AR	4	AR [cytosol] (R-HSA-5618082) AR [nucleoplasm] (R-HSA-446174) monoSUMO1-K386,520-AR [nucleoplasm] (R-HSA-4090320) PolyUb-AR [nucleoplasm] (R-HSA-6782984)	0.483	3
UniProt:Q92731 ESR2	5	ESR2 [cytosol] (R-HSA-9020970) ESR2 [nucleoplasm] (R-HSA-446165) Me-PalmS-ESR2 [plasma membrane] (R-HSA-9637787) PalmS-ESR2 [plasma membrane] (R-HSA-9021059) PalmS-ESR2 [cytosol] (R-HSA-9020979)	0.462	2

© 2025 Reactome

Cite Us!