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SLC6A2 [plasma membrane]
Stable Identifier
R-HSA-444009
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
NAT1, Sodium-dependent noradrenaline transporter, SC6A2_HUMAN
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Na+/Cl- dependent neurotransmitter transporters (Homo sapiens)
SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Homo sapiens)
SLC6A2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P23975 SLC6A2
Gene Names
SLC6A2, NAT1, NET1, SLC6A5
Chain
chain:1-617
Reference Genes
BioGPS Gene:6530 SLC6A2
COSMIC (genes):NAT1 SLC6A2
COSMIC (genes):NET1 SLC6A2
COSMIC (genes):SLC6A2 SLC6A2
COSMIC (genes):SLC6A5 SLC6A2
CTD Gene:6530 SLC6A2
dbSNP Gene:6530 SLC6A2
ENSEMBL:ENSG00000103546 SLC6A2
HGNC:11048 SLC6A2
KEGG:hsa:6530 SLC6A2
Monarch:6530 SLC6A2
NCBI Gene:6530 SLC6A2
OMIM:163970 SLC6A2
UCSC:P23975 SLC6A2
Reference Transcript
RefSeq:NM_001172504.1 SLC6A2
RefSeq:XM_011523295.1 SLC6A2
RefSeq:NM_001043.3 SLC6A2
RefSeq:NM_001172501.1 SLC6A2
RefSeq:NM_001172502.1 SLC6A2
RefSeq:XM_006721263.2 SLC6A2
Other Identifiers
11740324_a_at
11740325_a_at
11753967_a_at
16819109
210353_PM_s_at
210353_s_at
215715_PM_at
215715_at
216611_PM_s_at
216611_s_at
217621_PM_at
217621_at
239394_PM_at
239394_at
3661769
3661770
3661771
3661772
3661775
3661776
3661777
3661778
3661782
3661784
3661785
3661786
3661787
3661788
3661790
3661791
3661792
3661793
3661794
3661795
3661797
40402_at
65249_at
6530
70572_at
7995714
A_14_P106852
A_14_P116863
A_23_P358345
A_24_P910660
A_33_P3259022
A_33_P3394689
GE60137
GE689390
GO:0003779
GO:0005215
GO:0005326
GO:0005328
GO:0005330
GO:0005334
GO:0005515
GO:0005886
GO:0006836
GO:0006865
GO:0007268
GO:0008092
GO:0008504
GO:0009410
GO:0009986
GO:0015293
GO:0015844
GO:0015874
GO:0016020
GO:0022857
GO:0023052
GO:0030424
GO:0030672
GO:0032809
GO:0035725
GO:0042734
GO:0043014
GO:0046872
GO:0048265
GO:0048487
GO:0051583
GO:0051620
GO:0055085
GO:0070050
GO:0098810
HMNXSV003034135
HMNXSV003036203
Hs.14468.0.A1_3p_at
Hs.14468.0.A1_3p_x_at
Hs.208021.0.A1_3p_at
Hs.78036.1.S1_3p_at
ILMN_1765607
PH_hs_0004507
TC16000458.hg
X91117_rna1_at
g189257_3p_a_at
Other forms of this molecule
SLC6A2 A457P [plasma membrane]
Inferred To
Homologues of SLC6A2 [plasma membrane]
(Plasmodium falciparum)
SLC6A2 [plasma membrane]
(Bos taurus)
SLC6A2 [plasma membrane]
(Caenorhabditis elegans)
SLC6A2 [plasma membrane]
(Canis familiaris)
SLC6A2 [plasma membrane]
(Danio rerio)
SLC6A2 [plasma membrane]
(Drosophila melanogaster)
SLC6A2 [plasma membrane]
(Gallus gallus)
SLC6A2 [plasma membrane]
(Mus musculus)
SLC6A2 [plasma membrane]
(Plasmodium falciparum)
SLC6A2 [plasma membrane]
(Rattus norvegicus)
SLC6A2 [plasma membrane]
(Sus scrofa)
SLC6A2 [plasma membrane]
(Xenopus tropicalis)
Cross References
ZINC - World Drugs
SC6A2_HUMAN
Guide to Pharmacology - Targets
926
OpenTargets
ENSG00000103546
ENSEMBL
ENST00000219833
,
ENST00000379906
,
ENSP00000457473
,
ENSP00000457375
,
ENST00000568943
,
ENSP00000219833
,
ENSP00000369237
,
ENST00000567238
ZINC - FDA approved
SC6A2_HUMAN
ZINC - Substances
SC6A2_HUMAN
ZINC - Biogenic
SC6A2_HUMAN
ZINC target
P23975
PRO
P23975
GlyGen
P23975
PDB
8Y8Z
,
8YR2
,
8Y95
,
8HFL
,
8Y94
,
8Y91
,
8Y93
,
8Y92
,
8HFG
,
8HFE
,
8Y90
,
8HFI
,
8HFF
ZINC - Investigational
SC6A2_HUMAN
ZINC - Metabolites
SC6A2_HUMAN
HPA
ENSG00000103546-SLC6A2
Pharos - Targets
P23975
Orphanet
SLC6A2
ZINC - Predictions - Purchasable
SC6A2_HUMAN
HMDB Protein
HMDBP02154
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NRD5 PICK1
2
PICK1 [plasma membrane]
(R-HSA-416989)
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
0.508
3
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