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FPR3 [plasma membrane]
Stable Identifier
R-HSA-444569
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
FPRL2, N-formyl peptide receptor 3, FPR3_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
FPR3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
FPR3 [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
FPR3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
FPR3 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
FPR3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
FPR3 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Formyl peptide receptors bind formyl peptides and many other ligands (Homo sapiens)
FPRL2 receptor binds a wide range of ligands (Homo sapiens)
FPR3 [plasma membrane] (Homo sapiens)
FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
FPR3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P25089 FPR3
Gene Names
FPR3, FPRH1, FPRL2
Chain
chain:1-353
Reference Genes
BioGPS Gene:2359 FPR3
COSMIC (genes):FPR3 FPR3
CTD Gene:2359 FPR3
dbSNP Gene:2359 FPR3
ENSEMBL:ENSG00000187474 FPR3
ENSEMBL_homo_sapiens_GENE:ENSG00000187474.5 FPR3
HGNC:3828 FPR3
KEGG Gene (Homo sapiens):2359 FPR3
Monarch:2359 FPR3
NCBI Gene:2359 FPR3
OMIM:136539 FPR3
Reference Transcript
RefSeq:XM_011526687.2 FPR3
RefSeq:NM_002030.4 FPR3
Other Identifiers
11727942_a_at
11727943_a_at
16864756
214560_PM_at
214560_at
230422_PM_at
230422_at
2359
33092_at
3839921
3839924
3839925
3839926
3839927
3839928
3839929
3839930
51754_f_at
56824_at
8030866
ADDON002391.hg
A_14_P138538
A_23_P208167
A_33_P3247042
GE81102
GO:0002376
GO:0002430
GO:0004875
GO:0004930
GO:0004982
GO:0005515
GO:0005886
GO:0006935
GO:0006954
GO:0007165
GO:0007186
GO:0007200
GO:0007204
GO:0016020
GO:0023052
GO:0060089
HMNXSV003043500
Hs.158314.0.S1_3p_at
Hs.238936.0.A1_3p_at
ILMN_2203271
PH_hs_0021691
PH_hs_0030645
TC19000789.hg
Participates
as an input of
FPRL2 receptor binds a wide range of ligands (Homo sapiens)
as a component of
FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
Inferred To
LOC100491504 [plasma membrane]
(Xenopus tropicalis)
Fpr-rs4 [plasma membrane]
(Mus musculus)
Fpr-s1 [plasma membrane]
(Mus musculus)
Fpr2 [plasma membrane]
(Mus musculus)
Fpr2 [plasma membrane]
(Rattus norvegicus)
Fpr-rs3 [plasma membrane]
(Mus musculus)
FPR2 [plasma membrane]
(Canis familiaris)
Fpr-rs6 [plasma membrane]
(Mus musculus)
Fpr2l3 [plasma membrane]
(Rattus norvegicus)
Homologues of FPR3 [plasma membrane]
(Mus musculus)
Homologues of FPR3 [plasma membrane]
(Rattus norvegicus)
Homologues of FPR3 [plasma membrane]
(Xenopus tropicalis)
Fpr-rs7 [plasma membrane]
(Mus musculus)
LOC108648060 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
XP_011524989.1
,
NP_002021.3
Guide to Pharmacology - Targets
224
OpenTargets
ENSG00000187474
GeneCards
P25089
HPA
ENSG00000187474-FPR3
Ensembl
ENST00000595991
,
ENSP00000470471
,
ENST00000339223
,
ENSG00000187474
,
ENSP00000341821
PRO
P25089
Pharos - Targets
P25089
HMDB Protein
HMDBP07689
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