Zinc is an agonist of GPR39

Stable Identifier
R-HSA-444572
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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Zinc is an agonist of GPR39
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Zn2+ is a potent and effective agonist of GPR39, signaling effectively through the Gq pathway (Holst et al. 2004, 2007) and Gs (Zhang et al. 2005, Holst et al. 2007).
Literature References
PubMed ID Title Journal Year
18588883 Molecular mechanism of Zn2+ agonism in the extracellular domain of GPR39

Storjohann, L, Holst, B, Schwartz, TW

FEBS Lett 2008
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Authored
Jupe, S  (2009-10-21)
Reviewed
D'Eustachio, P  (2009-12-12)
Created
Jupe, S  (2009-10-23)
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