Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
NPS [extracellular region]
Stable Identifier
R-HSA-444711
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Neuropeptide S, NPS_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
NPSR1:NPS [plasma membrane] (Homo sapiens)
NPS [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
NPSR1:NPS [plasma membrane] (Homo sapiens)
NPS [extracellular region] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
NPSR1:NPS [plasma membrane] (Homo sapiens)
NPS [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
NPSR1:NPS [plasma membrane] (Homo sapiens)
NPS [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
NPSR1:NPS [plasma membrane] (Homo sapiens)
NPS [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
NPS [extracellular region] (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
NPSR1:NPS [plasma membrane] (Homo sapiens)
NPS [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
NPSR1:NPS [plasma membrane] (Homo sapiens)
NPS [extracellular region] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
NPSR1:NPS [plasma membrane] (Homo sapiens)
NPS [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
NPSR1:NPS [plasma membrane] (Homo sapiens)
NPS [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
NPSR1:NPS [plasma membrane] (Homo sapiens)
NPS [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gs [extracellular region] (Homo sapiens)
NPS [extracellular region] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Neuropeptide S receptor binds neuropeptide S (Homo sapiens)
NPS [extracellular region] (Homo sapiens)
NPSR1:NPS [plasma membrane] (Homo sapiens)
NPS [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P0C0P6 NPS
Gene Names
NPS
Chain
signal peptide:1-23, propeptide:24-67, peptide:70-89
Reference Genes
BioGPS Gene:594857 NPS
COSMIC (genes):NPS NPS
CTD Gene:594857 NPS
dbSNP Gene:594857 NPS
ENSEMBL:ENSG00000214285 NPS
ENSEMBL_homo_sapiens_GENE:ENSG00000214285.3 NPS
HGNC:33940 NPS
KEGG Gene (Homo sapiens):594857 NPS
Monarch:594857 NPS
NCBI Gene:594857 NPS
OMIM:609513 NPS
UCSC:P0C0P6 NPS
Reference Transcript
RefSeq:NM_001030013.1 NPS
Other Identifiers
11742672_at
16710540
3270191
3270192
3270212
594857
A_33_P3232290
GE751518
GO:0005576
GO:0007218
GO:0008542
GO:0010841
GO:0023052
GO:0032230
GO:0035249
GO:0045202
GO:0045760
GO:0050877
GO:0051968
HMNXSV003026236
ILMN_1824874
TC10000920.hg
Participates
as a member of
Ligands of GPCRs that activate Gs [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
as an input of
Neuropeptide S receptor binds neuropeptide S (Homo sapiens)
as a component of
NPSR1:NPS [plasma membrane] (Homo sapiens)
Inferred To
NPS [extracellular region]
(Bos taurus)
NPS [extracellular region]
(Canis familiaris)
NPS [extracellular region]
(Gallus gallus)
NPS [extracellular region]
(Sus scrofa)
Nps [extracellular region]
(Mus musculus)
Nps [extracellular region]
(Rattus norvegicus)
Cross References
RefSeq
NP_001025184.1
OpenTargets
ENSG00000214285
HPA
ENSG00000214285-NPS
GeneCards
P0C0P6
Ensembl
ENST00000398023
,
ENSG00000214285
,
ENSP00000381105
PRO
P0C0P6
Pharos - Targets
P0C0P6
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text