Reactome | BOC [plasma membrane]

BOC [plasma membrane]

Stable Identifier

R-HSA-445450

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Brother of CDO, BOC_HUMAN

Icon

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BWV1 BOC

Gene Names

BOC, UNQ604/PRO1190

Chain

signal peptide:1-30, chain:31-1114

Reference Genes

BioGPS Gene:91653 BOC

COSMIC (genes):BOC BOC

CTD Gene:91653 BOC

dbSNP Gene:91653 BOC

ENSEMBL:ENSG00000144857 BOC

HGNC:17173 BOC

KEGG Gene (Homo sapiens):91653 BOC

Monarch:91653 BOC

NCBI Gene:91653 BOC

OMIM:608708 BOC

UCSC:Q9BWV1 BOC

Reference Transcript

Other Identifiers

0004780059

11725693_a_at

16944010

224184_s_at

225990_at

2636338

2636339

2636340

2636342

2636362

2636363

2636364

2636382

2636384

2636388

2636389

2636391

2636392

2636395

2636396

2636398

2636399

2636400

2636401

2636405

2636406

2636407

2636411

2636413

2636415

2636416

2636417

2636418

2636419

2636460

52999_at

64423_s_at

8081686

91653

A_23_P257763

GE83630

GO:0000902

GO:0003674

GO:0005515

GO:0005575

GO:0005886

GO:0005887

GO:0007155

GO:0007165

GO:0007224

GO:0007411

GO:0008150

GO:0016020

GO:0016021

GO:0030154

GO:0040011

GO:0045663

GO:0048856

GO:0051149

HMNXSV003050373

HMNXSV003050750

Hs.153961.2.S2_3p_at

ILMN_1748384

ILMN_1803956

PH_hs_0023101

TC03000577.hg

g13506660_3p_a_at

Participates

as a component of

BOC:PTCH1 [ciliary membrane] (Homo sapiens)

Inferred To

boc [plasma membrane] (Danio rerio)

Boc [plasma membrane] (Mus musculus)

Boc [plasma membrane] (Rattus norvegicus)

BOC [plasma membrane] (Canis familiaris)

Cross References

RefSeq

XP_016862940.1, XP_005247948.1, NP_150279.1, NP_001288790.1, XP_005247949.1, XP_011511607.1

OpenTargets

ENSG00000144857

HPA

ENSG00000144857-BOC

GeneCards

Q9BWV1

Ensembl

ENSP00000347546, ENSP00000418663, ENSP00000273395, ENST00000355385, ENST00000495514, ENST00000273395, ENSG00000144857

PRO

Q9BWV1

Pharos - Targets

Q9BWV1

GlyGen

Q9BWV1

PDB

3N1P, 3N1M, 3N1G

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14623 IHH	10	CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [plasma membrane] (R-HSA-5362425) CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region] (R-HSA-445149) CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [endoplasmic reticulum lumen] (R-HSA-5362445) ub-N4glycoAsn-IHH(203-411) [endoplasmic reticulum lumen] (R-HSA-5362417) ub-N4glycoAsn-IHH(203-411) [cytosol] (R-HSA-5362393) 2xHC-IHH(28-411) [endoplasmic reticulum lumen] (R-HSA-5358277) N4glycoAsn-IHH(203-411) [endoplasmic reticulum lumen] (R-HSA-5358290) CHOL-IHH(28-202) [endoplasmic reticulum lumen] (R-HSA-5358293) N4glycoAsn-2xHC-IHH(28-411) [endoplasmic reticulum lumen] (R-HSA-5362390) IHH [extracellular region] (R-HSA-5362778)	0.558	2
UniProt:O43323 DHH	10	CHOL-N-palmitoyl-L-cysteine-DHH(23-198) [plasma membrane] (R-HSA-5362420) CHOL-N-palmitoyl-L-cysteine-DHH(23-198) [extracellular region] (R-HSA-445155) CHOL-N-palmitoyl-L-cysteine-DHH(23-198) [endoplasmic reticulum lumen] (R-HSA-5362442) ub-N4glycoAsn-DHH(199-396) [endoplasmic reticulum lumen] (R-HSA-5362411) ub-N4glycoAsn-DHH(199-396) [cytosol] (R-HSA-5362368) 2xHC-DHH(23-396) [endoplasmic reticulum lumen] (R-HSA-5358275) N4glycoAsn-DHH(199-396) [endoplasmic reticulum lumen] (R-HSA-5358287) CHOL-DHH(23-198) [endoplasmic reticulum lumen] (R-HSA-5358291) N4glycoAsn-2xHC-DHH(23-396) [endoplasmic reticulum lumen] (R-HSA-5362388) DHH(33-?) [extracellular region] (R-HSA-5362781)	0.558	2
UniProt:Q01721	1	Gas1 [plasma membrane] (R-MMU-449167)	0.524	2
UniProt:O35158	1	Cdon [plasma membrane] (R-RNO-197892)	0.524	2

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