Reactome | BOC [plasma membrane]

BOC [plasma membrane]

Stable Identifier

R-HSA-445450

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Brother of CDO, BOC_HUMAN

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BWV1 BOC

Gene Names

BOC, UNQ604/PRO1190

Chain

signal peptide:1-30, chain:31-1114

Reference Genes

BioGPS Gene:91653 BOC

COSMIC (genes):BOC BOC

CTD Gene:91653 BOC

dbSNP Gene:91653 BOC

ENSEMBL:ENSG00000144857 BOC

HGNC:17173 BOC

KEGG:hsa:91653 BOC

Monarch:91653 BOC

NCBI Gene:91653 BOC

OMIM:608708 BOC

UCSC:Q9BWV1 BOC

Reference Transcript

Participates

as a component of

BOC:PTCH1 [ciliary membrane] (Homo sapiens)

Inferred To

Boc [plasma membrane] (Mus musculus)

BOC [plasma membrane] (Bos taurus)

BOC [plasma membrane] (Canis familiaris)

BOC [plasma membrane] (Sus scrofa)

Cross References

ENSEMBL

ENST00000495514, ENSP00000347546, ENSP00000418663, ENSP00000273395, ENSP00000507783, ENST00000273395, ENST00000682979, ENSG00000144857, ENST00000355385

OpenTargets

ENSG00000144857

GeneCards

BOC

HPA

ENSG00000144857-BOC

PRO

Q9BWV1

Pharos - Targets

Q9BWV1

GlyGen

Q9BWV1

PDB

3N1P, 3N1G, 3N1M

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14623 IHH	10	CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region] (R-HSA-445149) CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [plasma membrane] (R-HSA-5362425) CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [endoplasmic reticulum lumen] (R-HSA-5362445) ub-N4glycoAsn-IHH(203-411) [endoplasmic reticulum lumen] (R-HSA-5362417) ub-N4glycoAsn-IHH(203-411) [cytosol] (R-HSA-5362393) 2xHC-IHH(28-411) [endoplasmic reticulum lumen] (R-HSA-5358277) N4glycoAsn-IHH(203-411) [endoplasmic reticulum lumen] (R-HSA-5358290) CHOL-IHH(28-202) [endoplasmic reticulum lumen] (R-HSA-5358293) N4glycoAsn-2xHC-IHH(28-411) [endoplasmic reticulum lumen] (R-HSA-5362390) IHH [extracellular region] (R-HSA-5362778)	0.558	2
UniProt:O43323 DHH	10	DHH(33-?) [extracellular region] (R-HSA-5362781) N4glycoAsn-2xHC-DHH(23-396) [endoplasmic reticulum lumen] (R-HSA-5362388) CHOL-DHH(23-198) [endoplasmic reticulum lumen] (R-HSA-5358291) N4glycoAsn-DHH(199-396) [endoplasmic reticulum lumen] (R-HSA-5358287) 2xHC-DHH(23-396) [endoplasmic reticulum lumen] (R-HSA-5358275) ub-N4glycoAsn-DHH(199-396) [cytosol] (R-HSA-5362368) ub-N4glycoAsn-DHH(199-396) [endoplasmic reticulum lumen] (R-HSA-5362411) CHOL-N-palmitoyl-L-cysteine-DHH(23-198) [endoplasmic reticulum lumen] (R-HSA-5362442) CHOL-N-palmitoyl-L-cysteine-DHH(23-198) [plasma membrane] (R-HSA-5362420) CHOL-N-palmitoyl-L-cysteine-DHH(23-198) [extracellular region] (R-HSA-445155)	0.558	2
UniProt:Q01721	1	Gas1 [plasma membrane] (R-MMU-449167)	0.524	2
UniProt:O35158	1	Cdon [plasma membrane] (R-RNO-197892)	0.524	2

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