Myosin Binds ATP

Stable Identifier
R-HSA-445700
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Myosin Binds ATP
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With the expulsion of ADP from the nucleotide binding pocket, ATP, if available will immediately bind myosin. When bound to ATP, the myosin head is in its low-energy configuration and the cross-bridge with the actin filament is disrupted.
Literature References
PubMed ID Title Journal Year
2526655 Characterization and differential expression of human vascular smooth muscle myosin light chain 2 isoform in nonmuscle cells

Kumar, CC, Mohan, SR, Zavodny, PJ, Narula, SK, Leibowitz, PJ

Biochemistry 1989
3780718 Isoforms of myosin and actin in human, monkey and rat myometrium. Comparison of pregnant and non-pregnant uterus proteins

Cavaillé, F, Janmot, C, Ropert, S, d'Albis, A

Eur J Biochem 1986
2764880 The distribution of heavy-chain isoforms of myosin in airways smooth muscle from adult and neonate humans

Mohammad, MA, Sparrow, MP

Biochem J 1989
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Orthologous Events
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Myosin Binds ATP (Gallus gallus)
Myosin Binds ATP (Mus musculus)
Myosin Binds ATP (Rattus norvegicus)
Myosin Binds ATP (Sus scrofa)
Myosin Binds ATP (Xenopus tropicalis)
Authored
Gillespie, ME  (2003-07-01)
Reviewed
Rush, MG  (2008-01-11)
Created
Gillespie, ME  (2009-11-05)
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