Reactome | PPARD [nucleoplasm]

PPARD [nucleoplasm]

Stable Identifier

R-HSA-446176

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Peroxisome proliferator-activated receptor delta, PPARD_HUMAN

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External Reference Information

External Reference

UniProt:Q03181 PPARD

Gene Names

PPARD, NR1C2, PPARB

Chain

chain:1-441

Reference Genes

COSMIC (genes):PPARD PPARD

dbSNP Gene:5467 PPARD

ENSEMBL:ENSG00000112033 PPARD

Participates

as a member of

NR [nucleoplasm] (Homo sapiens)

as a component of

RXRA:PPARD [nucleoplasm] (Homo sapiens)

Inferred To

ppardb [nucleoplasm] (Danio rerio)

Homologues of PPARD [nucleoplasm] (Caenorhabditis elegans)

nhr-2 [nucleoplasm] (Caenorhabditis elegans)

Eip75B [nucleoplasm] (Drosophila melanogaster)

Ppard [nucleoplasm] (Mus musculus)

nhr-7 [nucleoplasm] (Caenorhabditis elegans)

nhr-85 [nucleoplasm] (Caenorhabditis elegans)

PPARD [nucleoplasm] (Bos taurus)

PPARD [nucleoplasm] (Canis familiaris)

PPARD [nucleoplasm] (Gallus gallus)

PPARD [nucleoplasm] (Rattus norvegicus)

PPARD [nucleoplasm] (Sus scrofa)

ppard [nucleoplasm] (Xenopus tropicalis)

sex-1 [nucleoplasm] (Caenorhabditis elegans)

unc-55 [nucleoplasm] (Caenorhabditis elegans)

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P31749 AKT1	14	p-T308,S473-AKT1 [nucleoplasm] (R-HSA-198357) p-T308,S473-AKT1 [cytosol] (R-HSA-198356) p-S473-AKT1 [plasma membrane] (R-HSA-377265) AKT1 [plasma membrane] (R-HSA-199416) AKT1 [cytosol] (R-HSA-58252) p-T308-AKT1 [cytosol] (R-HSA-198634) p-Y315,Y326-AKT1 [cytosol] (R-HSA-8848757) p-T308,S473-AKT1 [plasma membrane] (R-HSA-199430) p-S473-AKT1 [cytosol] (R-HSA-9841264) AKT1 E17K [plasma membrane] (R-HSA-1500573) p-S473-AKT1 E17K [plasma membrane] (R-HSA-2243944) AKT1 E17K [cytosol] (R-HSA-2219526) p-T308,S473-AKT1 E17K [cytosol] (R-HSA-2243935) p-T308,S473-AKT1 E17K [nucleoplasm] (R-HSA-2399994)	0.553	3
UniProt:O60341 KDM1A	1	KDM1A [nucleoplasm] (R-HSA-996769)	0.508	2
UniProt:P15056 BRAF	20	p-S,T-BRAF [cytosol] (R-HSA-169856) BRAF(1-380)-MACF1(600-7388)fusion [cytosol] (R-HSA-6802402) p-BRAF(1-380)-MACF1(600-7388) fusion [cytosol] (R-HSA-6802536) BRAF E501G [cytosol] (R-HSA-9651132) BRAF D594N [cytosol] (R-HSA-6802299) BRAF D638E [cytosol] (R-HSA-9651125) BRAF G596R [cytosol] (R-HSA-6802385) BRAF D594V [cytosol] (R-HSA-6802305) BRAF G596V [cytosol] (R-HSA-9651138) BRAF G466E [cytosol] (R-HSA-6802374) BRAF D594G [cytosol] (R-HSA-6802295) BRAF L505H [cytosol] (R-HSA-9648845) BRAF F595L [cytosol] (R-HSA-6802316) BRAF L597V [cytosol] (R-HSA-6802397) BRAF G464E [cytosol] (R-HSA-6802369) BRAF N581D [cytosol] (R-HSA-9651152) BRAF E586K [cytosol] (R-HSA-6802308) BRAF V600K [cytosol] (R-HSA-6802502) BRAF A246P [cytosol] (R-HSA-9651123) BRAF G469V [cytosol] (R-HSA-9648620)	0.471	2

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