IRAK1 binds to MYD88 within the IL1R complex

Stable Identifier
R-HSA-446692
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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IRAK1 binds to MYD88 within the IL1R complex
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MYD88 recruits unphosphorylated, inactive IRAK1 to the IL1 receptor complex.
Literature References
PubMed ID Title Journal Year
9430229 MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

Henzel, WJ, Wesche, H, Li, S, Cao, Z, Shillinglaw, W

Immunity 1997
8599092 IRAK: a kinase associated with the interleukin-1 receptor

Henzel, WJ, Cao, Z, Gao, X

Science 1996
Participants
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Output
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as an event of
Orthologous Events
IRAK1 binds to MYD88 within the IL1R complex (Bos taurus)
IRAK1 binds to MYD88 within the IL1R complex (Canis familiaris)
IRAK1 binds to MYD88 within the IL1R complex (Mus musculus)
IRAK1 binds to MYD88 within the IL1R complex (Rattus norvegicus)
IRAK1 binds to MYD88 within the IL1R complex (Sus scrofa)
Authored
Ray, KP  (2010-05-17)
Reviewed
Pinteaux, E  (2010-05-17)
Created
Jupe, S  (2009-11-16)
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