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TAB3 [plasma membrane]
Stable Identifier
R-HSA-446879
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, MAP3K7IP3
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Homo sapiens)
NOD1/2 Signaling Pathway (Homo sapiens)
K63 polyubiquitinated RIP2 associates with the TAK1 complex (Homo sapiens)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:TAK1 complex [plasma membrane] (Homo sapiens)
TAK1 complex [plasma membrane] (Homo sapiens)
TAB2,TAB3 [plasma membrane] (Homo sapiens)
TAB3 [plasma membrane] (Homo sapiens)
TAK1 complex [plasma membrane] (Homo sapiens)
TAB2,TAB3 [plasma membrane] (Homo sapiens)
TAB3 [plasma membrane] (Homo sapiens)
TAK1 is activated (Homo sapiens)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:TAK1 complex [plasma membrane] (Homo sapiens)
TAK1 complex [plasma membrane] (Homo sapiens)
TAB2,TAB3 [plasma membrane] (Homo sapiens)
TAB3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8N5C8 TAB3
Gene Names
TAB3, MAP3K7IP3
Chain
initiator methionine:, chain:2-712
Reference Genes
BioGPS Gene:257397 TAB3
COSMIC (genes):TAB3 TAB3
CTD Gene:257397 TAB3
dbSNP Gene:257397 TAB3
ENSEMBL:ENSG00000157625 TAB3
HGNC:30681 TAB3
KEGG:hsa:257397 TAB3
Monarch:257397 TAB3
NCBI Gene:257397 TAB3
OMIM:300480 TAB3
UCSC:Q8N5C8 TAB3
Reference Transcript
RefSeq:XM_005274483.3 TAB3
RefSeq:NM_152787.4 TAB3
Other Identifiers
11741815_a_at
11741816_s_at
11746378_a_at
11746379_a_at
11752679_a_at
1552927_PM_at
1552927_at
1552928_PM_s_at
1552928_s_at
1558518_PM_at
1558518_at
17109901
227357_PM_at
227357_at
257397
4003961
4003962
4003963
4003964
4003965
4003966
4003967
4003968
4003969
4003970
4003971
4003972
4003973
4003975
4003976
4003977
4003978
4003979
4003980
4003983
4003984
4003985
4003986
4003987
4003988
4003989
4003990
4003992
4003993
4003994
4003996
4003998
4004010
47843_at
76839_at
8171901
88365_at
A_23_P305033
A_32_P162150
A_33_P3251347
GE562106
GE87145
GO:0005515
GO:0005783
GO:0005829
GO:0005886
GO:0008270
GO:0010008
GO:0010507
GO:0038061
GO:0042742
GO:0043123
GO:0043130
GO:0043226
GO:0046872
GO:0060090
GO:0070062
GO:0070530
GO:0098542
HMNXSV003011075
HMNXSV003023596
HMNXSV003039976
Hs.135055.0.A1_3p_at
Hs2.365565.1.S1_3p_s_at
Hs2.365565.2.S1_3p_x_at
ILMN_1671351
ILMN_1748272
PH_hs_0017470
PH_hs_0029904
PH_hs_0039191
TC0X000941.hg
Participates
as a member of
TAB2,TAB3 [plasma membrane] (Homo sapiens)
Other forms of this molecule
TAB3 [endosome membrane]
TAB3 [cytosol]
Inferred To
TAB3 [plasma membrane]
(Bos taurus)
TAB3 [plasma membrane]
(Canis familiaris)
TAB3 [plasma membrane]
(Sus scrofa)
tab3 [plasma membrane]
(Xenopus tropicalis)
Tab3 [plasma membrane]
(Mus musculus)
Tab3 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
XP_005274540.2
,
NP_690000.3
ENSEMBL
ENST00000378932
,
ENST00000288422
,
ENST00000378933
,
ENSP00000368212
,
ENSP00000368214
,
ENSP00000368215
,
ENSP00000288422
,
ENST00000378930
OpenTargets
ENSG00000157625
HPA
ENSG00000157625-TAB3
PRO
Q8N5C8
Pharos - Targets
Q8N5C8
GlyGen
Q8N5C8
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O43318 MAP3K7
10
PolyUb-MAP3K7 [cytosol]
(R-HSA-6782968)
MAP3K7 [plasma membrane]
(R-HSA-9012677)
p-T187-MAP3K7 [cytosol]
(R-HSA-206014)
K63polyUb-34,158-TAK1 [cytosol]
(R-HSA-5607643)
K63polyUb-34,158-p-T178,184,187,S192-TAK1 [cytosol]
(R-HSA-5607649)
p-MAP3K7 [cytosol]
(R-HSA-168163)
MAP3K7 [endosome membrane]
(R-HSA-450315)
p-T184,T187-MAP3K7 [endosome membrane]
(R-HSA-450332)
MAP3K7 [cytosol]
(R-HSA-168156)
p-T184,T187-MAP3K7 [cytosol]
(R-HSA-202527)
0.773
5
UniProt:Q14457 BECN1
4
BECN1 [cytosol]
(R-HSA-1632841)
p-S15-BECN1 [cytosol]
(R-HSA-5682391)
ISG15-K-BECN1 [cytosol]
(R-HSA-9853030)
K63polyUb-BECN1 [cytosol]
(R-HSA-6782989)
0.655
9
UniProt:Q15750 TAB1
6
TAB1 [cytosol]
(R-HSA-167923)
TAB1 [endosome membrane]
(R-HSA-450238)
TAB1(1-444) [cytosol]
(R-HSA-9729751)
TAB1(1-132) [cytosol]
(R-HSA-9729698)
TAB1(133-504) [cytosol]
(R-HSA-9729724)
TAB1(445-504) [cytosol]
(R-HSA-9729691)
0.643
5
UniProt:Q13526 PIN1
2
PIN1 [nucleoplasm]
(R-HSA-936016)
PIN1 [cytosol]
(R-HSA-9626823)
0.556
3
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