Other interleukin signaling

Stable Identifier
R-HSA-449836
DOI
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Interleukins are low molecular weight proteins that bind to cell surface receptors and act in an autocrine and/or paracrine fashion. They were first identified as factors produced by leukocytes but are now known to be produced by many other cells throughout the body. They have pleiotropic effects on cells which bind them, impacting processes such as tissue growth and repair, hematopoietic homeostasis, and multiple levels of the host defense against pathogens where they are an essential part of the immune system.
Literature References
PubMed ID Title Journal Year
21377040 Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases

Meyer, N, Akdis, M, Zimmermann, M, Ouaked, N, O'Mahony, L, Quaked, N, Gomez, E, Rhyner, C, Crameri, R, Klunker, S, Schaffartzik, A, Akdis, CA, Palomares, O, Fujita, H, Burgler, S, Zeller, S, Van De Veen, W, Eiwegger, T

J. Allergy Clin. Immunol. 2011
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