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GRIK2 [plasma membrane]
Stable Identifier
R-HSA-450192
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Glutamate receptor, ionotropic kainate 2, GRIK2_HUMAN, GluR6
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of kainate receptors upon glutamate binding (Homo sapiens)
Ionotropic activity of kainate receptors (Homo sapiens)
Activation of Ca-permeable Kainate Receptor (Homo sapiens)
Activation of Ca-permeable Kainate receptors (Homo sapiens)
Kainate receptor-glutamate complex [plasma membrane] (Homo sapiens)
Kainate Receptors [plasma membrane] (Homo sapiens)
GRIK 2 homomer [plasma membrane] (Homo sapiens)
GRIK2 [plasma membrane] (Homo sapiens)
GRIK1 and 2 heterotetramer [plasma membrane] (Homo sapiens)
GRIK2 [plasma membrane] (Homo sapiens)
GRIK4 heteromer with GRIK1/2/3 [plasma membrane] (Homo sapiens)
GRIK1, GRIK2, GRIK3 [plasma membrane] (Homo sapiens)
GRIK2 [plasma membrane] (Homo sapiens)
GRIK5 heteromer with GRIk1/2/3 [plasma membrane] (Homo sapiens)
GRIK1, GRIK2, GRIK3 [plasma membrane] (Homo sapiens)
GRIK2 [plasma membrane] (Homo sapiens)
kainate receptor binds glutamate (Homo sapiens)
Kainate Receptors [plasma membrane] (Homo sapiens)
GRIK 2 homomer [plasma membrane] (Homo sapiens)
GRIK2 [plasma membrane] (Homo sapiens)
GRIK1 and 2 heterotetramer [plasma membrane] (Homo sapiens)
GRIK2 [plasma membrane] (Homo sapiens)
GRIK4 heteromer with GRIK1/2/3 [plasma membrane] (Homo sapiens)
GRIK1, GRIK2, GRIK3 [plasma membrane] (Homo sapiens)
GRIK2 [plasma membrane] (Homo sapiens)
GRIK5 heteromer with GRIk1/2/3 [plasma membrane] (Homo sapiens)
GRIK1, GRIK2, GRIK3 [plasma membrane] (Homo sapiens)
GRIK2 [plasma membrane] (Homo sapiens)
Kainate receptor-glutamate complex [plasma membrane] (Homo sapiens)
Kainate Receptors [plasma membrane] (Homo sapiens)
GRIK 2 homomer [plasma membrane] (Homo sapiens)
GRIK2 [plasma membrane] (Homo sapiens)
GRIK1 and 2 heterotetramer [plasma membrane] (Homo sapiens)
GRIK2 [plasma membrane] (Homo sapiens)
GRIK4 heteromer with GRIK1/2/3 [plasma membrane] (Homo sapiens)
GRIK1, GRIK2, GRIK3 [plasma membrane] (Homo sapiens)
GRIK2 [plasma membrane] (Homo sapiens)
GRIK5 heteromer with GRIk1/2/3 [plasma membrane] (Homo sapiens)
GRIK1, GRIK2, GRIK3 [plasma membrane] (Homo sapiens)
GRIK2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13002 GRIK2
Gene Names
GRIK2, GLUR6
Chain
signal peptide:1-31, chain:32-908
Reference Genes
BioGPS Gene:2898 GRIK2
COSMIC (genes):GRIK2 GRIK2
CTD Gene:2898 GRIK2
dbSNP Gene:2898 GRIK2
ENSEMBL:ENSG00000164418 GRIK2
ENSEMBL_homo_sapiens_GENE:ENSG00000164418.22 GRIK2
HGNC:4580 GRIK2
KEGG Gene (Homo sapiens):2898 GRIK2
Monarch:2898 GRIK2
NCBI Gene:2898 GRIK2
OMIM:138244 GRIK2
UCSC:Q13002 GRIK2
Reference Transcript
RefSeq:NM_021956.4 GRIK2
RefSeq:NM_175768.3 GRIK2
RefSeq:XM_005266945.2 GRIK2
RefSeq:XM_011535777.2 GRIK2
RefSeq:XM_011535778.2 GRIK2
RefSeq:NM_001166247.1 GRIK2
Other Identifiers
11741955_a_at
11746867_a_at
11758524_s_at
1560142_PM_at
1560142_at
1563754_PM_at
1563754_at
17011217
213845_PM_at
213845_at
2898
2918981
2918983
2918986
2918987
2919001
2919002
2919003
2919016
2919017
2919018
2919032
2919033
2919036
2919037
2919042
2919044
2919045
2919057
2919062
2919063
2919080
2919082
2919084
2919085
2919087
2919088
2919089
2919090
3928259
39572_at
39573_at
8121225
A_14_P108416
A_14_P139842
A_23_P250136
A_24_P935839
A_32_P115796
A_33_P3307133
A_33_P3307144
A_33_P3307147
GE82629
GO:0000149
GO:0001662
GO:0004970
GO:0005215
GO:0005216
GO:0005234
GO:0005886
GO:0006811
GO:0006874
GO:0007215
GO:0007268
GO:0008066
GO:0008328
GO:0012501
GO:0014069
GO:0015276
GO:0015277
GO:0016020
GO:0019228
GO:0023052
GO:0030165
GO:0030424
GO:0030425
GO:0031624
GO:0031625
GO:0032839
GO:0032983
GO:0034220
GO:0035235
GO:0035249
GO:0038023
GO:0042391
GO:0042734
GO:0042802
GO:0043025
GO:0043113
GO:0043195
GO:0043204
GO:0043226
GO:0043524
GO:0043525
GO:0045202
GO:0045211
GO:0046328
GO:0048169
GO:0048172
GO:0050804
GO:0050806
GO:0050877
GO:0051402
GO:0051967
GO:0055065
GO:0055085
GO:0060079
GO:0060080
GO:0060089
GO:0097110
GO:0097471
GO:0098686
GO:0098815
GO:0098839
GO:0098978
GO:0099171
GO:0099505
GO:0099507
GO:0120169
GO:1904315
HMNXSV003056832
Hs.301676.0.S2_3p_at
Hs2.301676.4.S1_3p_at
Hs2.301676.4.S1_3p_s_at
Hs2.301676.5.S1_3p_at
Hs2.301676.5.S1_3p_x_at
ILMN_1661376
ILMN_1666934
ILMN_2396697
ILMN_2396702
PH_hs_0023669
TC06000836.hg
U16126_at
Participates
as a component of
GRIK 2 homomer [plasma membrane] (Homo sapiens)
GRIK1 and 2 heterotetramer [plasma membrane] (Homo sapiens)
as a member of
GRIK1, GRIK2, GRIK3 [plasma membrane] (Homo sapiens)
Other forms of this molecule
Edited GRIK2 (GluR6) [plasma membrane]
Inferred To
GluRIIC [plasma membrane]
(Drosophila melanogaster)
GluRIIA [plasma membrane]
(Drosophila melanogaster)
grik2 [plasma membrane]
(Xenopus tropicalis)
GluRIIE [plasma membrane]
(Drosophila melanogaster)
Homologues of GRIK2 [plasma membrane]
(Drosophila melanogaster)
GRIK2 [plasma membrane]
(Bos taurus)
GRIK2 [plasma membrane]
(Canis familiaris)
GRIK2 [plasma membrane]
(Drosophila melanogaster)
GRIK2 [plasma membrane]
(Gallus gallus)
GRIK2 [plasma membrane]
(Mus musculus)
GRIK2 [plasma membrane]
(Rattus norvegicus)
GRIK2 [plasma membrane]
(Sus scrofa)
Ghost homologue of GRIK2 [plasma membrane]
(Caenorhabditis elegans)
GluRIID [plasma membrane]
(Drosophila melanogaster)
Grik [plasma membrane]
(Drosophila melanogaster)
clumsy [plasma membrane]
(Drosophila melanogaster)
Cross References
RefSeq
XP_011534080.1
,
XP_011534079.1
,
NP_786944.1
,
NP_001159719.1
,
NP_068775.1
,
XP_005267002.1
ZINC - World Drugs
GRIK2_HUMAN
Guide to Pharmacology - Targets
451
OpenTargets
ENSG00000164418
ZINC - FDA approved
GRIK2_HUMAN
ZINC - Substances
GRIK2_HUMAN
ZINC - Biogenic
GRIK2_HUMAN
ZINC target
Q13002
PRO
Q13002
PDB
5CMM
,
3QXM
ZINC - Metabolites
GRIK2_HUMAN
GeneCards
Q13002
HPA
ENSG00000164418-GRIK2
Ensembl
ENSP00000358134
,
ENST00000682090
,
ENSP00000508130
,
ENSP00000508175
,
ENSP00000507424
,
ENSP00000397026
,
ENSG00000164418
,
ENST00000683215
,
ENST00000684068
,
ENST00000413795
,
ENST00000421544
,
ENSP00000405596
,
ENST00000369134
,
ENST00000369138
,
ENSP00000358130
Pharos - Targets
Q13002
ZINC - Predictions - Purchasable
GRIK2_HUMAN
Orphanet
18489
HMDB Protein
HMDBP01813
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