Reactome | YWHAZ [nucleoplasm]

YWHAZ [nucleoplasm]

Stable Identifier

R-HSA-450469

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

14-3-3zeta

Locations in the PathwayBrowser for interactor UniProt:Q6P1L5 F117B

Expand all

External Reference Information

External Reference

UniProt:P63104 YWHAZ

Gene Names

YWHAZ

Chain

chain:1-245

Reference Genes

BioGPS Gene:7534 YWHAZ

COSMIC (genes):YWHAZ YWHAZ

CTD Gene:7534 YWHAZ

dbSNP Gene:7534 YWHAZ

ENSEMBL:ENSG00000164924 YWHAZ

ENSEMBL_homo_sapiens_GENE:ENSG00000164924.18 YWHAZ

HGNC:12855 YWHAZ

KEGG Gene (Homo sapiens):7534 YWHAZ

Monarch:7534 YWHAZ

NCBI Gene:7534 YWHAZ

OMIM:601288 YWHAZ

UCSC:P63104 YWHAZ

Reference Transcript

Other Identifiers

11756181_x_at

11758667_x_at

11758711_x_at

11758750_x_at

11758751_at

11758752_x_at

1235_at

1556496_PM_a_at

1556496_a_at

17079711

17120418

200638_PM_s_at

200638_s_at

200639_PM_s_at

200639_s_at

200640_PM_at

200640_at

200641_PM_s_at

200641_s_at

214848_PM_at

214848_at

2574516

2574517

2924960

3146891

3146893

3146895

3146897

3146899

3146900

3146901

3146902

3146903

3146904

3146905

3146906

3146911

3146912

3146913

3146930

3146931

3146933

3146939

3146940

3146941

3146942

3146943

3146944

3146950

3146951

3146952

3146953

3146954

3146955

3204097

3204098

3238808

3238818

3238820

3262898

34642_at

36760_at

3694476

3749823

4005925

4005976

55272_at

7534

8152096

A_19_P00802601

A_24_P209571

A_24_P532478

GE548889

GE58115

GE59443

GE80033

GO:0000122

GO:0002376

GO:0003723

GO:0003824

GO:0004497

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005925

GO:0006351

GO:0006355

GO:0006468

GO:0007165

GO:0012501

GO:0016491

GO:0019901

GO:0023052

GO:0031410

GO:0031625

GO:0031982

GO:0034330

GO:0036211

GO:0042149

GO:0042470

GO:0042802

GO:0043066

GO:0043226

GO:0044325

GO:0045296

GO:0045824

GO:0048856

GO:0050815

GO:0051683

GO:0070062

GO:0070372

GO:0072562

GO:0090128

GO:0090168

GO:0098542

GO:0098978

GO:0140297

GO:0140311

GO:0140313

GO:1900181

GO:1904262

HMNXSV003006124

HMNXSV003052498

Hs.71848.0.S1_3p_at

Hs2.58429.1.S1_3p_s_at

ILMN_1669286

ILMN_1801928

M86400_at

PH_hs_0040263

TC08001485.hg

TC08002448.hg

TC08002449.hg

TC08002451.hg

TC10000164.hg

U79277_at

g13177678_3p_a_at

g4507952_3p_a_at

g899458_3p_a_at

p15857

Participates

as a component of

as an input of

Other forms of this molecule

YWHAZ [cytosol]

Inferred To

14-3-3zeta [nucleoplasm] (Drosophila melanogaster)

14-3-3I [nucleoplasm] (Plasmodium falciparum)

par-5 [nucleoplasm] (Caenorhabditis elegans)

ywhaz [nucleoplasm] (Xenopus tropicalis)

Homologues of YWHAZ [nucleoplasm] (Caenorhabditis elegans)

ftt-2 [nucleoplasm] (Caenorhabditis elegans)

ywhabl [nucleoplasm] (Danio rerio)

YWHAZ [nucleoplasm] (Bos taurus)

YWHAZ [nucleoplasm] (Canis familiaris)

YWHAZ [nucleoplasm] (Gallus gallus)

YWHAZ [nucleoplasm] (Sus scrofa)

Ywhaz [nucleoplasm] (Mus musculus)

Ywhaz [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001129172.1, XP_005251118.1, NP_663723.1, NP_001129174.1, NP_001129173.1, XP_016869300.1, NP_003397.1, XP_005251120.1, NP_001129171.1, XP_016869299.1

OpenTargets

ENSG00000164924

GeneCards

P63104

HPA

ENSG00000164924-YWHAZ

Ensembl

ENST00000419477, ENSG00000164924, ENSP00000395114, ENST00000353245, ENSP00000309503, ENSP00000379283, ENST00000395956, ENSP00000430072, ENST00000395957, ENST00000395958, ENST00000457309, ENST00000395951, ENSP00000379287, ENSP00000379288, ENST00000395953, ENSP00000379281, ENSP00000379286, ENSP00000398599, ENST00000522542

PRO

P63104

Pharos - Targets

P63104

HMDB Protein

HMDBP02552

PDB

7D8H, 6FNC, 6U2H, 7MFD, 7MFE, 5ULO, 5WXN, 1QJB, 5D2D, 7D8P, 4FJ3, 3RDH, 6YO8, 2O02, 6ZFD, 7ZIT, 1QJA, 6XAG, 5J31, 4ZDR, 5NAS, 8A9G, 1IB1, 5EWZ, 6YOS, 3NKX, 4WRQ, 6EWW, 7D9V, 5XY9, 5M37, 5M36, 2C1J, 7Q16, 6F09, 4N84, 5M35, 4N7Y, 6F08, 7MFF, 4HKC, 5EXA, 2WH0, 6FN9, 5D3F, 6ZFG, 4N7G, 6YMO, 4IHL, 2C1N, 6EJL, 8AH2, 5JM4, 4BG6, 6FNA, 6RLZ, 6FNB, 3CU8, 6Q0K, 6EF5

Interactors (347)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04049 RAF1	20	p-S338,Y340,Y341-RAF1 [cytosol] (R-HSA-5624465) p-S338-RAF1 [cytosol] (R-HSA-5624469) p-S621-RAF1 S259F [cytosol] (R-HSA-9656124) p-S621-RAF1 S257L [cytosol] (R-HSA-9656121) p-S621-RAF1 P261L [cytosol] (R-HSA-9656106) p-S621-RAF1 N262K [cytosol] (R-HSA-9656101) p-S621-RAF1 P261A [cytosol] (R-HSA-9656103) p-S621-RAF1 P261S [cytosol] (R-HSA-9656113) p-S621-RAF1 S259T [cytosol] (R-HSA-9656130) p-S621-RAF1 P261T [cytosol] (R-HSA-9656115) p-S621-RAF1 P261R [cytosol] (R-HSA-9656110) p-S621-RAF1 S259P [cytosol] (R-HSA-9656127) p-S621-RAF1 T260I [cytosol] (R-HSA-9656136) p-S621-RAF1 T260R [cytosol] (R-HSA-9656139) p-S621-RAF1 V263A [cytosol] (R-HSA-9656148) p-S621-RAF1 R256S [cytosol] (R-HSA-9656119) p-S621-RAF1 T491I [cytosol] (R-HSA-9656143) p-S621-RAF1 D486N [cytosol] (R-HSA-9656088) p-S621-RAF1 S427G [cytosol] (R-HSA-9656134) p-S621-RAF1 L613V [cytosol] (R-HSA-9656098)	0.966	35
UniProt:P27448 MARK3	1	MARK3 [cytosol] (R-HSA-5672591)	0.944	17
UniProt:P30305 CDC25B	3	p-S50,T69,S160,S321,S470-CDC25B [cytosol] (R-HSA-8863644) CDC25B [cytosol] (R-HSA-157412) CDC25B [nucleoplasm] (R-HSA-69734)	0.937	12
UniProt:P49815 TSC2	4	p-S939,S1130,T1462-TSC2 [cytosol] (R-HSA-165164) p-S939,T1462-TSC2 [cytosol] (R-HSA-199484) TSC2 [cytosol] (R-HSA-2980548) p-S1387-TSC2 [cytosol] (R-HSA-3132769)	0.937	12
UniProt:Q7KZI7 MARK2			0.929	12
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.924	17
UniProt:P15056 BRAF	20	BRAF(1-380)-MACF1(600-7388)fusion [cytosol] (R-HSA-6802402) p-BRAF(1-380)-MACF1(600-7388) fusion [cytosol] (R-HSA-6802536) BRAF E501G [cytosol] (R-HSA-9651132) BRAF D594N [cytosol] (R-HSA-6802299) BRAF D638E [cytosol] (R-HSA-9651125) BRAF G596R [cytosol] (R-HSA-6802385) BRAF D594V [cytosol] (R-HSA-6802305) BRAF G596V [cytosol] (R-HSA-9651138) BRAF G466E [cytosol] (R-HSA-6802374) BRAF D594G [cytosol] (R-HSA-6802295) BRAF L505H [cytosol] (R-HSA-9648845) BRAF F595L [cytosol] (R-HSA-6802316) BRAF L597V [cytosol] (R-HSA-6802397) BRAF G464E [cytosol] (R-HSA-6802369) BRAF N581D [cytosol] (R-HSA-9651152) BRAF E586K [cytosol] (R-HSA-6802308) BRAF V600K [cytosol] (R-HSA-6802502) BRAF A246P [cytosol] (R-HSA-9651123) BRAF G469V [cytosol] (R-HSA-9648620) BRAF T244P [cytosol] (R-HSA-9651165)	0.924	13
UniProt:Q02241 KIF23	3	KIF23 [nucleoplasm] (R-HSA-156709) p-S911,S912-KIF23 [nucleoplasm] (R-HSA-156695) KIF23 [cytosol] (R-HSA-1015863)	0.923	10
UniProt:O96013 PAK4	1	PAK4 [cytosol] (R-HSA-428461)	0.916	10
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.907	11
UniProt:Q92934 BAD	4	p-S99-BAD [cytosol] (R-HSA-198335) BAD [cytosol] (R-HSA-50662) BAD [mitochondrial outer membrane] (R-HSA-114242) p-S91-BAD [cytosol] (R-HSA-217297)	0.901	10
UniProt:P56524 HDAC4	3	polySUMO2,3-K559-HDAC4 [nucleoplasm] (R-HSA-4616029) monoSUMO1-K559-HDAC4 [nucleoplasm] (R-HSA-4616016) HDAC4 [nucleoplasm] (R-HSA-351581)	0.899	9
UniProt:P10398 ARAF	4	p-S299,S302,T452,T455,S582 ARAF [cytosol] (R-HSA-5672646) p-S299,S302,T452,T455,S582 ARAF [plasma membrane] (R-HSA-5672648) p-S582 ARAF [cytosol] (R-HSA-5672681) p-S214,S582 ARAF [cytosol] (R-HSA-5672639)	0.897	10
UniProt:P33176 KIF5B	3	KIF5B [cytosol] (R-HSA-265181) KIF5B(2-575)-p-7Y-ALK(1063-1620) fusion [cytosol] (R-HSA-9711937) KIF5B(2-575)-ALK(1063-1620) fusion [cytosol] (R-HSA-9711964)	0.895	7
UniProt:P40818 USP8	2	USP8 [cytosol] (R-HSA-917720) p-T945-USP8 [cytosol] (R-HSA-1358714)	0.895	7
UniProt:P54253 ATX1			0.882	13
UniProt:P46937 YAP1	8	p-Y407-YAP1 [cytosol] (R-HSA-9865208) p-S127-YAP1 [cytosol] (R-HSA-2028553) p-5S-YAP1 [cytosol] (R-HSA-2028554) p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) YAP1 [cytosol] (R-HSA-1253345) YAP1 [nucleoplasm] (R-HSA-1253322)	0.882	11
UniProt:Q8TEW0 PARD3	3	PARD3 [plasma membrane] (R-HSA-419980) PARD3 [cytosol] (R-HSA-419993) PARD3 [cell junction] (R-HSA-2134481)	0.88	10
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.879	11
UniProt:Q04917 YWHAH	1	YWHAH [cytosol] (R-HSA-1445107)	0.877	11
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.869	10
UniProt:Q9NSK0 KLC4	1	KLC4 [cytosol] (R-HSA-983244)	0.867	7
UniProt:Q86X27 RGPS2			0.867	8
UniProt:Q9H0B6 KLC2	1	KLC2 [cytosol] (R-HSA-983191)	0.867	7
UniProt:Q92974 ARHGEF2	1	ARHGEF2 [cytosol] (R-HSA-195101)	0.859	7
UniProt:P26045 PTPN3	3	PTPN3 [plasma membrane] (R-HSA-5490317) p-S459 PTPN3 [cytosol] (R-HSA-8868111) PTPN3 [cytosol] (R-HSA-8867650)	0.859	7
UniProt:Q9NYL2 M3K20			0.858	8
UniProt:O43524 FOXO3	11	p-S215 FOXO3 [nucleoplasm] (R-HSA-5687010) p-S215 FOXO3 [cytosol] (R-HSA-5687014) FOXO3 [cytosol] (R-HSA-5687032) p-S43,S173,S294,S325-FOXO3 [nucleoplasm] (R-HSA-8870627) p-S43,S173,S294,S325-FOXO3 [cytosol] (R-HSA-8870560) FOXO3(?-673) [mitochondrial matrix] (R-HSA-9841824) Ac-K271,K290-FOXO3(?-673) [mitochondrial matrix] (R-HSA-9841849) Ac-K242,K259,K271,K290,K569-FOXO3 [nucleoplasm] (R-HSA-9620514) p-T32,S253,S315-FOXO3 [cytosol] (R-HSA-9614413) p-T32,S253,S315-FOXO3 [nucleoplasm] (R-HSA-199289) FOXO3 [nucleoplasm] (R-HSA-199305)	0.851	6
UniProt:P27348 YWHAQ	1	YWHAQ [cytosol] (R-HSA-1445116)	0.848	12
UniProt:Q6PKG0 LARP1	1	LARP1 [cytosol] (R-HSA-9760421)	0.835	6
UniProt:Q9UQC2 GAB2	5	p-Y643-GAB2 [cytosol] (R-HSA-9677149) p-5Y-GAB2 [cytosol] (R-HSA-8855574) p-Y-GAB2 [cytosol] (R-HSA-912529) p-Y452,Y476,Y584-GAB2 [cytosol] (R-HSA-2685615) GAB2 [cytosol] (R-HSA-508239)	0.827	7
UniProt:Q7Z401 DENND4A	1	DENND4A [cytosol] (R-HSA-8876072)	0.816	7
UniProt:O75044 SRGAP2	1	SRGAP2 [cytosol] (R-HSA-195131)	0.816	6
UniProt:Q9Y4H2 IRS2	4	IRS2 [plasma membrane] (R-HSA-2428927) IRS2 [cytosol] (R-HSA-57528) p-Y-IRS2 [cytosol] (R-HSA-74774) p-Y-IRS2 [plasma membrane] (R-HSA-198334)	0.816	6
UniProt:Q9P0K7 RAI14			0.813	5
UniProt:Q5TCX8 M3K21			0.802	6
UniProt:Q99759 MAP3K3	1	MAP3K3 [cytosol] (R-HSA-507725)	0.802	6
UniProt:Q8WUI4 HDAC7	1	HDAC7 [nucleoplasm] (R-HSA-3004534)	0.802	5
UniProt:O60825 PFKFB2	1	PFKFB2 [cytosol] (R-HSA-71790)	0.802	6
UniProt:Q07866 KLC1	3	KLC1(1-420)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711978) KLC1(1-420)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711968) KLC1 [cytosol] (R-HSA-983284)	0.802	5
UniProt:Q9UQL6 HDAC5	1	HDAC5 [nucleoplasm] (R-HSA-3004533)	0.802	5
UniProt:Q00537 CDK17			0.802	6
UniProt:Q9UQB8 BAIAP2	1	BAIAP2 [cytosol] (R-HSA-442574)	0.802	8
UniProt:O60343 TBC1D4	2	p-5S,T642-TBC1D4 [cytoplasmic vesicle membrane] (R-HSA-1445101) TBC1D4 [cytoplasmic vesicle membrane] (R-HSA-1445122)	0.792	5
UniProt:Q12802 AKAP13	1	AKAP13 [cytosol] (R-HSA-2975983)	0.792	5
UniProt:O00750 PIK3C2B	1	PIK3C2B [cytosol] (R-HSA-1604619)	0.792	5
UniProt:Q9P2M7 CGN	1	CGN [cell junction] (R-HSA-2134478)	0.792	6
UniProt:O60292 SI1L3			0.792	6
UniProt:Q6WCQ1 MPRIP	2	MPRIP(2-1015)-RAF1(279-648) fusion [cytosol] (R-HSA-6802406) MPRIP(2-1015)-p-RAF1(279-648) fusion [cytosol] (R-HSA-6802540)	0.792	5
UniProt:P31947 SFN	1	SFN [cytosol] (R-HSA-1445105)	0.792	8
UniProt:Q9P0L2 MARK1			0.788	5
UniProt:Q9Y2U5 M3K2			0.788	5
UniProt:Q12778 FOXO1	5	p-S218-FOXO1 [nucleoplasm] (R-HSA-5692651) Ac-K245,K248,K265-FOXO1 [nucleoplasm] (R-HSA-9626942) FOXO1 [nucleoplasm] (R-HSA-199300) p-T24,S256,S319-FOXO1 [nucleoplasm] (R-HSA-199306) p-T24,S256,S319-FOXO1 [cytosol] (R-HSA-211158)	0.788	6
UniProt:O14639 ABLIM1	1	ABLIM1 [cytosol] (R-HSA-416771)	0.786	6
UniProt:Q99683 MAP3K5	1	MAP3K5 [cytosol] (R-HSA-167709)	0.779	5
UniProt:Q6R327 RICTOR	1	RICTOR [cytosol] (R-HSA-198632)	0.774	5
UniProt:Q7L804 RAB11FIP2	1	RAB11FIP2 [cytoplasmic vesicle membrane] (R-HSA-2028707)	0.774	5
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.772	6
UniProt:Q5T5U3 ARHGAP21	1	ARHGAP21 [cytosol] (R-HSA-8873918)	0.763	5
UniProt:Q13625 TP53BP2	1	TP53BP2 [nucleoplasm] (R-HSA-6799780)	0.763	5
UniProt:Q9Y2K2 SIK3			0.762	8
UniProt:O95544 NADK	1	NADK [cytosol] (R-HSA-197282)	0.758	4
UniProt:Q5PRF9 SMAG2			0.758	4
UniProt:Q96F86 EDC3	1	EDC3 [cytosol] (R-HSA-429997)	0.749	4
UniProt:Q9Y2J2 EPB41L3	1	EPB41L3 [cytosol] (R-HSA-6797563)	0.749	4
UniProt:Q8NHQ8 RASF8			0.745	5
UniProt:Q92625 ANS1A			0.745	5
UniProt:Q5TCZ1 SH3PXD2A	1	SH3PXD2A [cytosol] (R-HSA-8941242)	0.745	5
UniProt:Q86SQ0 PHLB2			0.745	5
UniProt:Q9P2F8 SI1L2			0.745	5
UniProt:O60333 KIF1B	1	KIF1B [cytosol] (R-HSA-8849378)	0.745	5
UniProt:Q6IQ23 PKHA7			0.745	5
UniProt:Q5VZ89 DENND4C	1	DENND4C [cytosol] (R-HSA-5216192)	0.745	5
UniProt:Q6UUV9 CRTC1	1	CRTC1 [nucleoplasm] (R-HSA-5656488)	0.745	5
UniProt:Q86TI0 TBC1D1	2	TBC1D1 [cytoplasmic vesicle membrane] (R-HSA-1454718) p-S237-TBC1D1 [cytosol] (R-HSA-1454673)	0.745	5
UniProt:Q07002 CDK18			0.744	5
UniProt:Q6ICG6 K0930			0.744	4
UniProt:Q7Z6B7 SRGAP1	1	SRGAP1 [cytosol] (R-HSA-428453)	0.744	4
UniProt:Q6P597 KLC3	1	KLC3 [cytosol] (R-HSA-983232)	0.744	4
UniProt:O43896 KIF1C	1	KIF1C [cytosol] (R-HSA-8849365)	0.738	4
UniProt:P30291 WEE1	3	p-WEE1 [nucleoplasm] (R-HSA-156491) p-S53-WEE1 [nucleoplasm] (R-HSA-156694) WEE1 [nucleoplasm] (R-HSA-69253)	0.734	5
UniProt:O75592 MYCB2			0.731	4
UniProt:Q5VV41 ARHGEF16	1	ARHGEF16 [cytosol] (R-HSA-2976623)	0.731	4
UniProt:Q02156 PRKCE	2	PRKCE [cytosol] (R-HSA-58202) p-T566,T710,S729-PRKCE [plasma membrane] (R-HSA-198260)	0.729	7
UniProt:Q9NYF3 FA53C			0.725	4
UniProt:Q53ET0 CRTC2	1	CRTC2 [nucleoplasm] (R-HSA-8931951)	0.725	6
UniProt:Q5JSL3 DOCK11	1	DOCK11 [cytosol] (R-HSA-1012996)	0.725	4
UniProt:Q15032 R3HD1			0.725	4
UniProt:Q96Q42 ALS2	1	ALS2 [cytosol] (R-HSA-8875298)	0.725	4
UniProt:O94988 FAM13A	1	FAM13A [cytosol] (R-HSA-3364049)	0.725	4
UniProt:Q6NUK4 REEP3			0.725	4
UniProt:Q9Y3M2 CBY1	3	pS20-CBY1 [nucleoplasm] (R-HSA-3769356) CBY1 [nucleoplasm] (R-HSA-3769210) pS20-CBY1 [cytosol] (R-HSA-3769354)	0.725	4
UniProt:P22681 CBL	20	PolyUb,p-Y-CBL [cytosol] (R-HSA-9763893) CBL R420G [cytosol] (R-HSA-9706203) CBL R420Q [cytosol] (R-HSA-9706186) CBL Y371H [cytosol] (R-HSA-9706680) CBL H398Y [cytosol] (R-HSA-9706639) CBL P417A [cytosol] (R-HSA-9706636) CBL S376F [cytosol] (R-HSA-9706643) CBL E366_Q409del [cytosol] (R-HSA-9706179) CBL del366-477 [cytosol] (R-HSA-9706176) CBL R499L [cytosol] (R-HSA-9706678) CBL L380P [cytosol] (R-HSA-9706630) CBL L287R [cytosol] (R-HSA-9706693) CBL L380R [cytosol] (R-HSA-9706635) CBL G375P [cytosol] (R-HSA-9706219) CBL P417L [cytosol] (R-HSA-9706634) CBL H398Q [cytosol] (R-HSA-9706633) CBL P417R [cytosol] (R-HSA-9706632) CBL R499* [cytosol] (R-HSA-9706670) CBL H398R [cytosol] (R-HSA-9706638) CBL H398P [cytosol] (R-HSA-9706637)	0.725	4
UniProt:P10636 MAPT	3	MAPT(422-758) [cytosol] (R-HSA-350642) MAPT(2-421) [cytosol] (R-HSA-350628) MAPT [cytosol] (R-HSA-201574)	0.723	8
UniProt:Q14153 FA53B			0.708	4
UniProt:P00519 ABL1	6	p-Y393-ABL1 [cytosol] (R-HSA-9865161) p-Y226,Y393-ABL1 [nucleoplasm] (R-HSA-8985251) ABL1 [cytosol] (R-HSA-375987) p-Y226,Y393-ABL1 [cytosol] (R-HSA-8942610) ABL1 [nucleoplasm] (R-HSA-5686579) p-S456-ABL1 [nucleoplasm] (R-HSA-5686576)	0.708	4
UniProt:O94875 SRBS2			0.707	4
UniProt:O94915 FRYL			0.706	4
UniProt:Q4KWH8 PLCH1	1	PLCH1 [plasma membrane] (R-HSA-2023859)	0.706	4
UniProt:Q7Z460 CLASP1	1	CLASP1 [cytosol] (R-HSA-376230)	0.706	4
UniProt:Q9H6H4 REEP4			0.706	4
UniProt:O43379 WDR62			0.706	4
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.706	22
UniProt:Q13009 TIAM1	2	p-Y829-TIAM1 [cytosol] (R-HSA-3928461) TIAM1 [cytosol] (R-HSA-195013)	0.706	4
UniProt:P47974 ZFP36L2	1	ZFP36L2 [cytosol] (R-HSA-9819194)	0.706	4
UniProt:Q86W92 PPFIBP1	5	PPFIBP1 [cytosol] (R-HSA-6799300) PPFIBP1(1-349)insK-ALK(1058-1620) fusion [cytosol] (R-HSA-9711955) PPFIBP1(1-232)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711976) PPFIBP1(1-232)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711963) PPFIBP1(1-349)insK-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711961)	0.695	4
UniProt:P06733 ENO1	1	ENO1 [cytosol] (R-HSA-71437)	0.692	3
UniProt:P25705 ATP5F1A	3	ATP5A1(1-553) [mitochondrial intermembrane space] (R-HSA-1267978) ATP5A1(1-553) [cytosol] (R-HSA-1267955) ATP5F1A [mitochondrial matrix] (R-HSA-164575)	0.688	4
UniProt:Q9UDY2 TJP2	4	TJP2 [plasma membrane] (R-HSA-351862) TJP2(?-?) [plasma membrane] (R-HSA-351897) TJP2 [cytosol] (R-HSA-2064412) TJP2 [nucleoplasm] (R-HSA-2064410)	0.688	3
UniProt:P04792 HSBP1	3	HSPB1 [cytosol] (R-HSA-450563) p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.678	4
UniProt:P57059 SIK1	1	SIK1 [nucleoplasm] (R-HSA-5656504)	0.677	5
UniProt:O95685 PPR3D			0.675	4
UniProt:O75122 CLASP2	1	CLASP2 [cytosol] (R-HSA-376252)	0.671	6
UniProt:O14654 IRS4	2	p-Y-IRS4 [plasma membrane] (R-HSA-2424302) IRS4 [plasma membrane] (R-HSA-2424297)	0.671	4
UniProt:Q7L8J4 3BP5L			0.669	3
UniProt:P05783 KRT18	1	KRT18 [cytosol] (R-HSA-201582)	0.669	3
UniProt:P30307 CDC25C	8	p-T48,T67,S122,T130,S168,S214-CDC25C [cytosol] (R-HSA-8863654) p-S191-CDC25C [nucleoplasm] (R-HSA-6802968) p-S216-CDC25C [cytosol] (R-HSA-75003) p-S216-CDC25C [nucleoplasm] (R-HSA-156496) CDC25C [nucleoplasm] (R-HSA-69741) CDC25C [cytosol] (R-HSA-157879) p-S198-CDC25C [cytosol] (R-HSA-8981697) p-S198-CDC25C [nucleoplasm] (R-HSA-156668)	0.669	3
UniProt:P08670 VIM	11	VIM(2-85) [cytosol] (R-HSA-350264) VIM(86-466) [cytosol] (R-HSA-350294) VIM(430-466) [cytosol] (R-HSA-350316) VIM(2-429) [cytosol] (R-HSA-350317) VIM(260-466) [cytosol] (R-HSA-350314) VIM(2-259) [cytosol] (R-HSA-350323) VIM [cytosol] (R-HSA-201600) Vimentin [late endosome lumen] (R-HSA-9660019) Vimentin [microtubule organizing center] (R-HSA-9657898) Vimentin [cytosol] (R-HSA-9646687) Vimentin [lysosomal lumen] (R-HSA-9659977)	0.669	3
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.669	3
UniProt:Q9Y4H4 GPSM3	1	GPSM3 [cytosol] (R-HSA-8949486)	0.666	7
UniProt:Q15884 EREP1			0.659	4
UniProt:P23528 CFL1	3	CFL1 [cytosol] (R-HSA-350751) p-S3-CFL1 [cytosol] (R-HSA-399813) CFL1 [extracellular region] (R-HSA-350747)	0.656	3
UniProt:P30304 CDC25A	6	PolyUb-CDC25A [cytosol] (R-HSA-6782810) CDC25A [nucleoplasm] (R-HSA-143487) CDC25A [cytosol] (R-HSA-157410) p-S124-CDC25A [nucleoplasm] (R-HSA-143488) p-S124-CDC25A [cytosol] (R-HSA-69588) p-S40,S116,S261-CDC25A [nucleoplasm] (R-HSA-8863634)	0.656	3
UniProt:P61587 RND3	1	RND3 [plasma membrane] (R-HSA-9696265)	0.655	11
UniProt:P42345 MTOR	2	MTOR [nucleoplasm] (R-HSA-5083674) MTOR [cytosol] (R-HSA-165662)	0.65	3
UniProt:Q9P0V3 SH3BP4	1	SH3BP4 [cytosol] (R-HSA-8866227)	0.65	3
UniProt:P07910 HNRNPC	3	HNRNPC [cytosol] (R-HSA-9715136) SUMO1-K250-HNRNPC [nucleoplasm] (R-HSA-4570543) HNRNPC [nucleoplasm] (R-HSA-71933)	0.65	3
UniProt:O14744 PRMT5	3	p-Y297,304,307-PRMT5 [nucleoplasm] (R-HSA-5211300) PRMT5 [nucleoplasm] (R-HSA-5205609) PRMT5 [cytosol] (R-HSA-191876)	0.646	3
UniProt:Q9UJ41 RABGEF1	2	RABGEF1 [cytosol] (R-HSA-8875419) RABGEF1 [early endosome membrane] (R-HSA-2029032)	0.643	3
UniProt:Q12840 KIF5A	1	KIF5A [cytosol] (R-HSA-983190)	0.643	3
UniProt:P15822 ZEP1			0.643	3
UniProt:Q16877 PFKFB4	1	PFKFB4 [cytosol] (R-HSA-71798)	0.643	3
UniProt:Q8IVT5 KSR1	5	p-S311,S406 KSR1 [cytosol] (R-HSA-5672654) KSR1 [cytosol] (R-HSA-5672587) p-S311 KSR1 [cytosol] (R-HSA-5672652) p-S311,Y602 KSR1 [plasma membrane] (R-HSA-5672659) p-S311,Y602 KSR1 [cytosol] (R-HSA-5672656)	0.643	3
UniProt:P37235 HPCL1			0.643	3
UniProt:Q15276 RABEP1	1	RABEP1 [early endosome membrane] (R-HSA-2029004)	0.643	3
UniProt:Q08AE8 SPIR1			0.643	3
UniProt:Q9NYB9 ABI2	2	ABI2 [cytosol] (R-HSA-1671647) p-4S-ABI2 [cytosol] (R-HSA-2029003)	0.643	3
UniProt:P68431 HIST1H3G	20	2xAcK-HIST1H3A [nucleoplasm] (R-HSA-427507) Me1K5-H3C1 [nucleoplasm] (R-HSA-9677683) Ack-Me3K5-HIST1H3A [nucleoplasm] (R-HSA-4551293) AcK-Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4551291) AcK-Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4551292) Me2aR27-HIST1H3A [nucleoplasm] (R-HSA-5229052) Me2aR18-HIST1H3A [nucleoplasm] (R-HSA-5229062) Me2sR9-HIST1H3A [nucleoplasm] (R-HSA-5211328) Me2sR3-HIST1H3A [nucleoplasm] (R-HSA-5218935) AcK9,14-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8870893) AcK14,18,79-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871271) AcK9,14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871306) AcK14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871294) AcK9,14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8865596) AcK14,18-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871295) AcK14,18,79-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871288) AcK14,18-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871299) AcK14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871286) Me2K28-HIST1H3A [nucleoplasm] (R-HSA-4754193) MeK37-HIST1H3A [nucleoplasm] (R-HSA-4722135)	0.643	3
UniProt:Q9H4L5 OSBPL3	1	OSBPL3 [cytosol] (R-HSA-8867532)	0.643	3
UniProt:O43822 CF410			0.643	3
UniProt:Q00536 CDK16			0.643	3
UniProt:Q86VP3 PACS2			0.643	3
UniProt:Q96GV9 MACIR			0.643	3
UniProt:Q9UBF8 PI4KB	2	PI4KB [cytosol] (R-HSA-1604615) PI4KB [Golgi membrane] (R-HSA-1806202)	0.643	3
UniProt:Q61337 Bad	6	phospho-Bad [cytosol] (R-MMU-217297) Bad [mitochondrial outer membrane] (R-MMU-114242) p-S136-Bad [cytosol] (R-MMU-3139049) Bad [cytosol] (R-MMU-3139043) Bad [cytosol] (R-MMU-50662) phospho-Bad [cytosol] (R-MMU-198335)	0.643	3
UniProt:Q02750 MAP2K1	20	MAP2K1(9-393) [cytosol] (R-HSA-5211353) MAP2K1(2-8) [cytosol] (R-HSA-5211342) MAP2K1 F53S [cytosol] (R-HSA-9652034) MAP2K1 D67N [cytosol] (R-HSA-9652016) MAP2K1 Q56P [cytosol] (R-HSA-9652064) MAP2K1 E203K [cytosol] (R-HSA-9652023) MAP2K1 V60E [cytosol] (R-HSA-9652067) MAP2K1 P124S [cytosol] (R-HSA-9652062) MAP2K1 Y130C [cytosol] (R-HSA-9652101) MAP2K1 C121S [cytosol] (R-HSA-9652013) MAP2K1 G128V [cytosol] (R-HSA-9652047) MAP2K1 F53L [cytosol] (R-HSA-9652031) MAP2K1 K57N [cytosol] (R-HSA-9652050) MAP2K1 K57T [cytosol] (R-HSA-9652052) MAP2K1 F53V [cytosol] (R-HSA-9652038) MAP2K1 D67Y [cytosol] (R-HSA-9652019) MAP2K1 G128D [cytosol] (R-HSA-9652043) MAP2K1 P124L [cytosol] (R-HSA-9652056) MAP2K1 F53Y [cytosol] (R-HSA-9652041) MAP2K1 L42_K57del [cytosol] (R-HSA-9652026)	0.643	6
UniProt:Q5SQI0 ATAT1	1	ATAT [cytosol] (R-HSA-5618184)	0.643	3
UniProt:Q9H4A3 WNK1	1	WNK1 [cytosol] (R-HSA-2672391)	0.64	3
UniProt:Q01113 IL9R	2	p-Y407-IL9R [plasma membrane] (R-HSA-8985904) IL9R [plasma membrane] (R-HSA-449790)	0.635	5
UniProt:P67828 KC1A			0.632	4
UniProt:Q9P0K1 ADAM22	1	ADAM22 [plasma membrane] (R-HSA-5678678)	0.626	5
UniProt:P54256-2 HAP1			0.619	4
UniProt:P10636-3 MAPT			0.618	9
UniProt:Q99959 PKP2	2	PKP2 [cornified envelope] (R-HSA-8847734) PKP2 [plasma membrane] (R-HSA-6814393)	0.615	3
UniProt:Q7Z309 PBIR2			0.615	3
UniProt:Q8N350 CBARP			0.615	3
UniProt:O95208 EPN2	1	EPN2 [cytosol] (R-HSA-8865828)	0.615	3
UniProt:Q96N67 DOCK7	1	DOCK7 [cytosol] (R-HSA-1012970)	0.615	3
UniProt:Q8N8E3 CE112			0.615	3
UniProt:Q5VT97 SYDE2	1	SYDE2 [cytosol] (R-HSA-200589)	0.615	3
UniProt:Q9UJF2 RASAL2	1	RASAL2 [cytosol] (R-HSA-5658224)	0.615	3
UniProt:Q5THJ4 VP13D			0.615	3
UniProt:Q6P1L5 F117B			0.615	3
UniProt:Q96NE9 FRMD6			0.615	3
UniProt:Q9BZF3 OSBPL6	1	OSBPL6 [cytosol] (R-HSA-8867534)	0.615	3
UniProt:O43166 SIPA1L1	1	SPAR [cytosol] (R-HSA-6794278)	0.615	3
UniProt:Q15831 STK11	2	STK11 [cytosol] (R-HSA-380954) STK11 [nucleoplasm] (R-HSA-164119)	0.61	6
UniProt:Q5SW79 CE170			0.604	3
UniProt:P30793 GCH1	1	GCH1 [cytosol] (R-HSA-1474127)	0.602	4
UniProt:Q29495 SNAT			0.602	3
UniProt:Q16890 TPD52L1	2	TPD52L1 [cytoplasmic vesicle lumen] (R-HSA-434220) TPD52L1 [Golgi lumen] (R-HSA-434331)	0.593	3
UniProt:P84198 VIME			0.591	5
UniProt:P17612 PRKACA	4	PRKACA [mitochondrial matrix] (R-HSA-9838291) PRKACA [ciliary base] (R-HSA-5610402) PRKACA [nucleoplasm] (R-HSA-111936) PRKACA [cytosol] (R-HSA-57844)	0.59	2
UniProt:Q13310 PABP4			0.589	2
UniProt:P62995 TRA2B	2	TRA2B [cytosol] (R-HSA-9715137) TRA2B [nucleoplasm] (R-HSA-8850859)	0.589	2
UniProt:Q14978 NOLC1			0.589	2
UniProt:O00273 DFFA	6	DFFA [cytosol] (R-HSA-211221) DFFA(1-?) [nucleoplasm] (R-HSA-211228) DFFA(225-331) [nucleoplasm] (R-HSA-211188) DFFA(118-224) [nucleoplasm] (R-HSA-211205) DFFA(118-331) [nucleoplasm] (R-HSA-211199) DFFA(1-117) [nucleoplasm] (R-HSA-211185)	0.589	2
UniProt:Q9P0K1-3 ADAM22			0.581	3
UniProt:P16104 H2AFX	7	Me2sR4-H2AFX [nucleoplasm] (R-HSA-5218317) H2AFX [nucleoplasm] (R-HSA-56151) p-Y143-H2AFX [nucleoplasm] (R-HSA-5683942) p-S140,Y143-H2AFX [nucleoplasm] (R-HSA-5683953) p-S140-H2AFX [nucleoplasm] (R-HSA-75170) K63PolyUb-K14,K16,p-S140-H2AFX [nucleoplasm] (R-HSA-5682847) H2AFX [extracellular region] (R-HSA-977583)	0.577	6
UniProt:P55072 VCP	8	Me3K315-VCP [cytosol] (R-HSA-8932209) VCP [endoplasmic reticulum membrane] (R-HSA-8943105) VCP [nucleoplasm] (R-HSA-5643745) VCP [secretory granule lumen] (R-HSA-6801039) VCP [ficolin-1-rich granule lumen] (R-HSA-6800425) VCP [extracellular region] (R-HSA-6806191) VCP [azurophil granule lumen] (R-HSA-6800438) VCP [cytosol] (R-HSA-1181251)	0.573	2
UniProt:Q12923 PTPN13	2	PTPN13 [plasma membrane] (R-HSA-8870318) PTPN13 [nucleoplasm] (R-HSA-9008915)	0.569	3
UniProt:O15049 N4BP3			0.569	3
UniProt:P10636-8 MAPT	3	p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) MAPT-8 [cytosol] (R-HSA-9619519)	0.569	10
UniProt:Q9Y2H2 INPP5F	1	INPP5F [early endosome membrane] (R-HSA-8849952)	0.569	3
UniProt:O00443 PIK3C2A	3	PIK3C2A [Golgi membrane] (R-HSA-432679) PIK3C2A [cytosol] (R-HSA-1604624) PIK3C2A [cytoplasmic vesicle membrane] (R-HSA-432683)	0.569	3
UniProt:P63104 YWHAZ	2	YWHAZ [nucleoplasm] (R-HSA-450469) YWHAZ [cytosol] (R-HSA-206099)	0.564	3
UniProt:Q16658 FSCN1	1	FSCN1 [cytosol] (R-HSA-6789835)	0.564	3
UniProt:P06576 ATP5F1B	6	ATP5F1B [mitochondrial matrix] (R-HSA-164576) ATP5B(1-47) [mitochondrial matrix] (R-HSA-8986172) ATP5B(1-529) [cytosol] (R-HSA-1267973) ATP5B(1-529) [mitochondrial intermembrane space] (R-HSA-1267985) ATP5B(1-529) [mitochondrial inner membrane] (R-HSA-1299440) ATP5B [mitochondrial inner membrane] (R-HSA-1299441)	0.564	2
UniProt:Q14204 DYNC1H1	3	DYNC1H1 [extracellular region] (R-HSA-6806223) DYNC1H1 [azurophil granule lumen] (R-HSA-6799155) DYNC1H1 [cytosol] (R-HSA-380285)	0.564	2
UniProt:P02545 LMNA	3	LMNA(1-646) [nuclear envelope] (R-HSA-535479) LMNA(1-567)-RAF1(279-648) fusion [cytosol] (R-HSA-6802399) LMNA(1-567)-p-RAF1(279-648) fusion [cytosol] (R-HSA-6802537)	0.564	2
UniProt:Q6Y7W6 GGYF2			0.564	2
UniProt:P27708 CAD	1	CAD [cytosol] (R-HSA-73452)	0.564	2
UniProt:Q8WWI1 LMO7	3	LMO7(1-1073)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9713460) LMO7(1-1073)-ALK(1058-1620) fusion [cytosol] (R-HSA-9713457) LMO7 [cytosol] (R-HSA-8862589)	0.564	2
UniProt:Q9UHB6 LIMA1			0.564	2
UniProt:Q69YN4 VIR			0.564	2
UniProt:P23396 RPS3	2	RPS3 [nucleoplasm] (R-HSA-6798714) RPS3 [cytosol] (R-HSA-72369)	0.564	2
UniProt:P62158 CALM			0.564	2
UniProt:Q9Y2A7 NCKAP1	1	NCKAP1 [cytosol] (R-HSA-200979)	0.564	2
UniProt:O15151 MDM4	5	PolyUb-MDM4 [nucleoplasm] (R-HSA-6782502) p-S403-MDM4 [nucleoplasm] (R-HSA-349461) p-S346,S367,S403-MDM4 [nucleoplasm] (R-HSA-349441) PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm] (R-HSA-6804938) MDM4 [nucleoplasm] (R-HSA-349430)	0.564	2
UniProt:Q71U36 TUBA1A	9	AcK-TUBA1A [cytosol] (R-HSA-5618312) Ac K40 TUBA1A [axonemal microtubule] (R-HSA-5624852) TUBA1A folding intermediate [cytosol] (R-HSA-392805) TUBA1A unfolded [cytosol] (R-HSA-392767) L-isoglutamyl polyglycyl-TUBA1A [cytosol] (R-HSA-8867428) Polyglutamyl-TUBA1A [cytosol] (R-HSA-8867408) TUBA1A(1-450) [cytosol] (R-HSA-8955577) TUBA1A [cytosol] (R-HSA-191689) TUBA1A [axonemal microtubule] (R-HSA-5610433)	0.564	4
UniProt:Q6AWC2 WWC2			0.564	2
UniProt:P42704 LRPPRC	1	LRPPRC [mitochondrial matrix] (R-HSA-5336174)	0.564	2
UniProt:Q15154 PCM1	1	PCM1 [cytosol] (R-HSA-380308)	0.564	2
UniProt:Q9Y4D8 HECD4			0.564	2
UniProt:Q8NHH9 ATLA2			0.564	2
UniProt:Q14C86 GAPVD1	1	GAPVD1 [cytosol] (R-HSA-8871123)	0.564	2
UniProt:Q9BSJ8 ESYT1	2	ESYT1 [plasma membrane] (R-HSA-9715081) ESYT1 [endoplasmic reticulum membrane] (R-HSA-8857672)	0.564	2
UniProt:P0C0S8 H2AC11	11	K63polyUb-HIST1H2AG [nucleoplasm] (R-HSA-6783237) Ub-HIST1H2AG [nucleoplasm] (R-HSA-6782508) Ack6-HIST1H2AG [nucleoplasm] (R-HSA-4568595) Me2aR30-HIST1H2AG [nucleoplasm] (R-HSA-5244582) MeR30-HIST1H2AG [nucleoplasm] (R-HSA-5244560) Me2aR4-HIST1H2AG [nucleoplasm] (R-HSA-5244587) MeR4-HIST1H2AG [nucleoplasm] (R-HSA-5244623) Me2aR12-HIST1H2AG [nucleoplasm] (R-HSA-5229305) MeR12-HIST1H2AG [nucleoplasm] (R-HSA-5229206) HIST1H2AG [nucleoplasm] (R-HSA-212084) Ack-HIST1H2AG [nucleoplasm] (R-HSA-4551311)	0.564	2
UniProt:Q15007 WTAP	1	WTAP [nucleoplasm] (R-HSA-6789461)	0.564	2
UniProt:Q9Y4G8 RAPGEF2	1	RAPGEF2 [cytosol] (R-HSA-5672599)	0.564	2
UniProt:P60709 ACTB	5	Unfolded ACTB [cytosol] (R-HSA-390462) ACTB [nucleoplasm] (R-HSA-3321990) ACTB [cytosol] (R-HSA-201861) ACTB [lysosomal membrane] (R-HSA-196160) ACTB [plasma membrane] (R-HSA-196016)	0.564	3
UniProt:O14980 XPO1	2	XPO1 [nucleoplasm] (R-HSA-165529) XPO1 [cytosol] (R-HSA-165539)	0.564	2
UniProt:O60573 EIF4E2	1	EIF4E2 [cytosol] (R-HSA-1678822)	0.564	2
UniProt:Q9BZ23 PANK2	1	PANK2(111-570) [mitochondrial intermembrane space] (R-HSA-196803)	0.564	2
UniProt:P25054 APC	20	APC R213* [cytosol] (R-HSA-9666924) APC C1410* [cytosol] (R-HSA-9666925) APC K1310* [cytosol] (R-HSA-9666926) APC R499* [cytosol] (R-HSA-9666927) APC R1450* [cytosol] (R-HSA-5251499) APC G1357* [cytosol] (R-HSA-9666940) APC L1488* [cytosol] (R-HSA-9666941) APC S1400* [cytosol] (R-HSA-9666942) APC S1346* [cytosol] (R-HSA-9666943) APC R405* [cytosol] (R-HSA-9666936) APC S1281* [cytosol] (R-HSA-9666937) APC E1573* [cytosol] (R-HSA-9666938) APC R805* [cytosol] (R-HSA-9666939) APC R1386* [cytosol] (R-HSA-9666932) APC S1327* [cytosol] (R-HSA-9666933) APC E1209* [cytosol] (R-HSA-9666934) APC Q1469* [cytosol] (R-HSA-9666935) APC R564* [cytosol] (R-HSA-9666928) APC E1536* [cytosol] (R-HSA-9666929) APC G1288* [cytosol] (R-HSA-9666930)	0.564	2
UniProt:P68104 EEF1A1	7	Me3K79-EEF1A1 [cytosol] (R-HSA-8932212) Me3K318-EEF1A1 [cytosol] (R-HSA-8932419) EEF1A1 [secretory granule lumen] (R-HSA-6801479) EEF1A1 [extracellular region] (R-HSA-6806456) EEF1A1 [ficolin-1-rich granule lumen] (R-HSA-6801528) EEF1A1 [cytosol] (R-HSA-156905) EEF1A1 [lysosomal membrane] (R-HSA-9626022)	0.564	2
UniProt:Q9NPI6 DCP1A	1	DCP1A [cytosol] (R-HSA-430043)	0.564	2
UniProt:Q96B36 AKT1S1	4	AKT1S1 [nucleoplasm] (R-HSA-5083637) p-T246-AKT1S1 [cytosol] (R-HSA-377124) p-S183,T246-AKT1S1 [cytosol] (R-HSA-200163) AKT1S1 [cytosol] (R-HSA-200155)	0.564	2
UniProt:P62805 H4C1	17	polySUMO3-HIST1H4 [nucleoplasm] (R-HSA-4570531) monoSUMO1-HIST1H4 [nucleoplasm] (R-HSA-4570518) 4xAcK-HIST1H4A [nucleoplasm] (R-HSA-427390) AcK5,12-HIST1H4A [nucleoplasm] (R-HSA-212078) AcK13-HIST1H4 [nucleoplasm] (R-HSA-4568744) Me2aR4-HIST1H4 [nucleoplasm] (R-HSA-5229015) Me2sR4-HIST1H4 [nucleoplasm] (R-HSA-4754243) MeR4-HIST1H4 [nucleoplasm] (R-HSA-4754240) Me3K21-HIST1H4 [nucleoplasm] (R-HSA-5651656) HIST1H4A [extracellular region] (R-HSA-977569) AcK17-HIST1H4 [nucleoplasm] (R-HSA-427469) AcK6-HIST1H4 [nucleoplasm] (R-HSA-4568748) AcK9-HIST1H4 [nucleoplasm] (R-HSA-4568758) MeK21-HIST1H4 [nucleoplasm] (R-HSA-5423110) AcK-HIST1H4 [nucleoplasm] (R-HSA-3451124) Me2K21-HIST1H4 [nucleoplasm] (R-HSA-5651652) HIST1H4 [nucleoplasm] (R-HSA-181902)	0.564	3
UniProt:P26358 DNMT1	2	monoSUMO1-K-DNMT1 [nucleoplasm] (R-HSA-4655353) DNMT1 [nucleoplasm] (R-HSA-212181)	0.564	2
UniProt:P06748 NPM1	11	monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1 [granular component] (R-HSA-9017702) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679)	0.564	2
UniProt:P31327 CPS1	1	CPS1 [mitochondrial matrix] (R-HSA-70544)	0.564	2
UniProt:P10636-2 MAPT			0.558	2
UniProt:P36897 TGFBR1	13	Ub-TGFBR1 [plasma membrane] (R-HSA-8869461) p-4S,T185,T186-TGFBR1 W242* [plasma membrane] (R-HSA-3656504) p-4S,T185,T186-TGFBR1 P327Qfs8 [plasma membrane] (R-HSA-3656505) p-4S,T185,T186-TGFBR1 L354Nfs4 [plasma membrane] (R-HSA-3656506) p-4S,T185,T186-TGFBR1 R414* [plasma membrane] (R-HSA-3656508) p-4S,T185,T186-TGFBR1 D269_Q324del [plasma membrane] (R-HSA-3656509) TGFBR1 G52R [plasma membrane] (R-HSA-3656368) TGFBR1 C41Y [plasma membrane] (R-HSA-3656328) TGFBR1 N45S [plasma membrane] (R-HSA-3656348) TGFBR1 P83L [plasma membrane] (R-HSA-3656341) TGFBR1 P83S [plasma membrane] (R-HSA-3656326) TGFBR1 [plasma membrane] (R-HSA-170839) p-4S,T185,T186-TGFBR1 [plasma membrane] (R-HSA-170849)	0.556	4
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.556	3
UniProt:Q86Z20 CC125			0.556	3
UniProt:Q9NRI5 DISC1			0.553	3
UniProt:Q99459 CDC5L	1	CDC5L [nucleoplasm] (R-HSA-5420887)	0.553	2
UniProt:P60520 GABARAPL2	3	GABARAPL2 [autophagosome membrane] (R-HSA-5683633) GABARAPL2(1-117) [cytosol] (R-HSA-5682641) GABARAPL2 [cytosol] (R-HSA-5671758)	0.547	2
UniProt:Q9Y2D8 ADIP			0.547	2
UniProt:P29172 TAU			0.544	2
UniProt:Q6P6S3 BSPRY			0.543	3
UniProt:P55196 AFDN			0.536	2
UniProt:Q96RK0 CIC			0.536	2
UniProt:P47736 RAP1GAP	1	RAP1GAP [cytosol] (R-HSA-392493)	0.536	2
UniProt:P09651 HNRNPA1	2	HNRNPA1 [cytosol] (R-HSA-9727902) HNRNPA1 [nucleoplasm] (R-HSA-71927)	0.536	2
UniProt:Q9Y2I8 WDR37			0.527	2
UniProt:Q6VAB6 KSR2	1	KSR2 [cytosol] (R-HSA-5672589)	0.527	6
UniProt:Q13136 PPFIA1	1	PPFIA1 [cytosol] (R-HSA-383377)	0.527	2
UniProt:Q9BPZ7 MAPKAP1	1	MAPKAP1 [cytosol] (R-HSA-3006620)	0.527	2
UniProt:O43900 PRIC3			0.527	4
UniProt:Q9UBS9 SUCO			0.527	2
UniProt:P31629 ZEP2			0.527	2
UniProt:Q8TD55 PLEKHO2	2	PLEKHO2 [extracellular region] (R-HSA-6806484) PLEKHO2 [ficolin-1-rich granule lumen] (R-HSA-6801067)	0.527	2
UniProt:Q9NQU5 PAK6	1	PAK6 [cytosol] (R-HSA-428454)	0.527	2
UniProt:Q9BVC5 C2orf49	1	C2orf49 [nucleoplasm] (R-HSA-5696780)	0.527	2
UniProt:P36405 ARL3	1	ARL3 [cilium] (R-HSA-5618182)	0.527	3
UniProt:Q8IZ21 PHAR4			0.527	2
UniProt:Q16875 PFKFB3	1	PFKFB3 [cytosol] (R-HSA-71794)	0.527	2
UniProt:P11274 BCR	4	BCR(1-584)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1838979) p-Y177-BCR(1-584)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1839041) BCR(1-584)-FGFR1(429-822) fusion [cytosol] (R-HSA-1604524) BCR [cytosol] (R-HSA-195200)	0.527	2
UniProt:Q96S53 TESK2			0.527	2
UniProt:P49761 CLK3			0.527	2
UniProt:Q8WYL5 SSH1			0.527	2
UniProt:A0JNW5 BLTP3B	1	UHRF1BP1L [cytosol] (R-HSA-9715180)	0.527	2
UniProt:Q14680 MELK			0.527	2
UniProt:P07101 TH	1	TH [cytosol] (R-HSA-2980863)	0.527	2
UniProt:Q13470 TNK1			0.527	2
UniProt:Q96GL9 F163A			0.527	3
UniProt:Q9NYI0 PSD3			0.527	2
UniProt:Q96N96 SPATA13	1	SPATA13 [cytosol] (R-HSA-9690931)	0.527	2
UniProt:Q8IX15 HOMEZ			0.527	2
UniProt:Q13671 RIN1	1	RIN1 [cytosol] (R-HSA-8875287)	0.527	2
UniProt:Q7Z3C6 ATG9A	1	ATG9A [phagophore assembly site membrane] (R-HSA-5671732)	0.527	2
UniProt:Q9H1R3 MYLK2			0.527	3
UniProt:Q9NZQ3 NCKIPSD	1	NCKIPSD [cytosol] (R-HSA-2197671)	0.527	2
UniProt:Q6ZV73 FGD6			0.527	2
UniProt:P19484 TFEB	1	TFEB [nucleoplasm] (R-HSA-9857368)	0.527	4
UniProt:Q32P44 EMAL3			0.527	2
UniProt:Q9HB20 PLEKHA3	1	PLEKHA3 [Golgi membrane] (R-HSA-8870513)	0.527	2
UniProt:Q9UJM3 ERRFI			0.527	2
UniProt:P57078 RIPK4			0.527	2
UniProt:Q86X02 CDR2L			0.527	4
UniProt:Q15139 PRKD1	1	PRKD1 [cytosol] (R-HSA-58210)	0.527	2
UniProt:P49796 RGS3	1	RGS3 [plasma membrane] (R-HSA-8849410)	0.527	2
UniProt:Q9H8N7 ZN395			0.527	3
UniProt:Q969F2 NKD2			0.527	2
UniProt:Q9BZ29 DOCK9	1	DOCK9 [cytosol] (R-HSA-1012981)	0.527	2
UniProt:Q9HB19 PLEKHA2	1	PLEKHA2 [plasma membrane] (R-HSA-8870329)	0.527	2
UniProt:P05787 KRT8	1	KRT8 [cytosol] (R-HSA-446043)	0.527	3
UniProt:P36507 MAP2K2	12	MAP2K2(1-10) [cytosol] (R-HSA-5211334) MAP2K2(11-400) [cytosol] (R-HSA-5211337) MAP2K2 C125S [cytosol] (R-HSA-9652070) MAP2K2 P128Q [cytosol] (R-HSA-9652082) MAP2K2 V35M [cytosol] (R-HSA-9652086) MAP2K2 Y134C [cytosol] (R-HSA-9652089) p-S222,S226-MAP2K2 [cytosol] (R-HSA-169292) MAP2K2 [cytosol] (R-HSA-59504) p-S,T-MAP2K2 [cytosol] (R-HSA-109848) MAP2K2 N126D [cytosol] (R-HSA-9652079) MAP2K2 L46F [cytosol] (R-HSA-9652076) MAP2K2 F57C [cytosol] (R-HSA-9652073)	0.527	4
UniProt:Q9BYG4 PARD6G	2	PARD6G [plasma membrane] (R-HSA-418192) PARD6G [cytosol] (R-HSA-419967)	0.527	2
UniProt:Q96FS4 SIPA1	1	SIPA1 [cytosol] (R-HSA-392495)	0.527	2
UniProt:Q9ULR3 PPM1H			0.527	2
UniProt:Q3KQU3 MA7D1			0.527	2
UniProt:O60282 KIF5C	1	KIF5C [cytosol] (R-HSA-3878117)	0.527	2
UniProt:P31946-2 YWHAB			0.527	2
UniProt:Q9BZF9 UACA	1	UACA [cytosol] (R-HSA-6804636)	0.527	2
UniProt:P27986 PIK3R1	16	p-Y-PIK3R1 [cytosol] (R-HSA-9680647) PIK3R1 G376R [plasma membrane] (R-HSA-2399717) PIK3R1 K379E [plasma membrane] (R-HSA-8944148) PIK3R1 Y463_L466del [plasma membrane] (R-HSA-2399546) PIK3R1 H450_E451del [plasma membrane] (R-HSA-2399545) PIK3R1 R574_T576del [plasma membrane] (R-HSA-2399544) PIK3R1 D560Y [plasma membrane] (R-HSA-2399421) PIK3R1 N564D [plasma membrane] (R-HSA-2399427) PIK3R1 K459del [plasma membrane] (R-HSA-2399554) PIK3R1 N564K [plasma membrane] (R-HSA-2399431) PIK3R1 D560H [plasma membrane] (R-HSA-2399432) PIK3R1 R574I [plasma membrane] (R-HSA-2399536) PIK3R1 R574T [plasma membrane] (R-HSA-2399540) K63polyUb-PIK3R1 [cytosol] (R-HSA-3080572) PIK3R1 [cytosol] (R-HSA-74789) PIK3R1 [plasma membrane] (R-HSA-198365)	0.527	2
UniProt:P07359 GP1BA	6	GP1BA G249S [plasma membrane] (R-HSA-9844280) GP1BA G249V [plasma membrane] (R-HSA-9844257) GP1BA M255V [plasma membrane] (R-HSA-9844240) GP1BA [plasma membrane] (R-HSA-55861) GP1BA D251Y [plasma membrane] (R-HSA-9844197) GP1BA W246L [plasma membrane] (R-HSA-9844258)	0.527	2
UniProt:P29074 PTPN4	2	PTPN4 [nucleoplasm] (R-HSA-9008925) PTPN4 [cytosol] (R-HSA-8877173)	0.527	2
UniProt:Q07352 ZFP36L1	3	p-S54,S92,S203-p-ZFP36L1 [cytosol] (R-HSA-450384) ZFP36L1 [cytosol] (R-HSA-450547) p-S92,S203-ZFP36L1 [cytosol] (R-HSA-450618)	0.527	2
UniProt:Q9P2Y5 UVRAG	2	UVRAG [cytosol] (R-HSA-5668884) UVRAG [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9730510)	0.527	2
UniProt:Q08495 DMTN	1	DMTN [cytosol] (R-HSA-5216222)	0.527	2
UniProt:Q9NQC7 CYLD	3	K48polyUb-K338, K530-CYLD [cytosol] (R-HSA-9818664) p-S418-CYLD [cytosol] (R-HSA-5212667) CYLD [cytosol] (R-HSA-741420)	0.527	2
UniProt:Q96L34 MARK4	1	MARK4 [cytosol] (R-HSA-5626653)	0.527	2
UniProt:Q63767	4	phospho-Bcar1 [cytosol] (R-RNO-372645) phospho-Bcar1 [cytosol] (R-RNO-5218739) phospho-Bcar1 [cytosol] (R-RNO-8848723) Bcar1 [cytosol] (R-RNO-201625)	0.527	2
UniProt:Q8WX92 NELFB	3	NELFB [nucleoplasm] (R-HSA-112427) NELFB [cytosol] (R-HSA-9603526) NELFB [mitochondrial outer membrane] (R-HSA-9603553)	0.527	2
UniProt:P62993 GRB2	1	GRB2 [cytosol] (R-HSA-8983328)	0.527	3
UniProt:A0MZ66 SHTN1	1	KIAA1598 [cytosol] (R-HSA-443599)	0.527	2
UniProt:P29353 SHC1	5	p-Y427-SHC1 [cytosol] (R-HSA-74684) p-Y349,Y350-SHC1 [cytosol] (R-HSA-180276) p-Y349,Y350,Y427-SHC1 [cytosol] (R-HSA-912321) SHC1 [cytosol] (R-HSA-74680) p-Y-SHC1 [cytosol] (R-HSA-162568)	0.527	2
UniProt:Q8NFH8 REPS2	1	REPS2 [cytosol] (R-HSA-432938)	0.524	2
UniProt:P28290 ITPI2			0.519	2
UniProt:O00257-3 CBX4			0.499	2
UniProt:Q8IVL1 NAV2			0.483	2
UniProt:Q9NR80 ARHGEF4	1	ARHGEF4 [cytosol] (R-HSA-2976635)	0.483	2
UniProt:Q5VT25 CDC42BPA	1	CDC42BPA [cytosol] (R-HSA-419871)	0.483	2
UniProt:Q9BXF6 RFIP5			0.483	2
UniProt:Q13480 GAB1	4	GAB1 [cytosol] (R-HSA-179795) p-5Y-GAB1 [cytosol] (R-HSA-180344) p-Y627,Y659-GAB1 [cytosol] (R-HSA-180496) p-Y-GAB1 [cytosol] (R-HSA-8855306)	0.483	2
UniProt:Q76I76 SSH2			0.483	2
UniProt:Q6GYQ0 RALGAPA1	1	RALGAPA1 [cytosol] (R-HSA-9714672)	0.483	2
UniProt:Q8TEH3 DENND1A	2	DENND1A [cytosol] (R-HSA-8877594) p-S536, S538 DENND1A [cytosol] (R-HSA-8933370)	0.483	2
UniProt:Q5M775 CYTSB			0.483	2
UniProt:Q3V6T2 CCDC88A	1	CCDC88A [cytosol] (R-HSA-9715191)	0.483	2
UniProt:Q5T0W9 FAM83B	1	FAM83B [cytosol] (R-HSA-9715184)	0.483	2
UniProt:Q14669 TRIP12	1	TRIP12 [cytosol] (R-HSA-976046)	0.483	2
UniProt:P78524 ST5	1	ST5 [cytosol] (R-HSA-8876091)	0.483	2
UniProt:Q86UU1 PHLB1			0.483	2
UniProt:Q6ZWE6 PKHM3			0.483	2
UniProt:A7KAX9 ARHGAP32	1	ARHGAP32 [cytosol] (R-HSA-195134)	0.483	2
UniProt:Q9ULJ3 ZBT21			0.483	2
UniProt:O14974 PPP1R12A	4	p-S473-PPP1R12A [nucleoplasm] (R-HSA-3002801) p-T696,S852-PPP1R12A [cytosol] (R-HSA-419079) PPP1R12A [cytosol] (R-HSA-419070) p-T696-PPP1R12A [cytosol] (R-HSA-5668956)	0.483	2
UniProt:Q9Y4F5 C170B			0.483	2
UniProt:O94885 SASH1			0.483	2
UniProt:Q9UPV9 TRAK1	3	TRAK1 [cytosol] (R-HSA-5578870) TRAK1(1-325)-RAF1(279-648) fusion [cytosol] (R-HSA-6802474) TRAK1(1-325)-p-RAF1(279-648) fusion [cytosol] (R-HSA-6802554)	0.483	2
UniProt:Q6UUV7 CRTC3	1	CRTC3 [nucleoplasm] (R-HSA-8931950)	0.483	2
UniProt:Q5T5Y3 CAMP1			0.483	2
UniProt:Q9Y6M7 SLC4A7 </