Reactome | SET [nucleoplasm]

SET [nucleoplasm]

Stable Identifier

R-HSA-451201

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Protein SET, SET_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P62750 RPL23A

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External Reference Information

External Reference

UniProt:Q01105 SET

Gene Names

SET

Chain

initiator methionine:, chain:2-290

Reference Genes

COSMIC (genes):SET SET

dbSNP Gene:6418 SET

ENSEMBL:ENSG00000119335 SET

Participates

as a component of

as an input of

Inferred To

Set [nucleoplasm] (Drosophila melanogaster)

Set [nucleoplasm] (Mus musculus)

Set [nucleoplasm] (Rattus norvegicus)

SET [nucleoplasm] (Bos taurus)

SET [nucleoplasm] (Canis familiaris)

SET [nucleoplasm] (Gallus gallus)

SET [nucleoplasm] (Sus scrofa)

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BT49 THAP7			0.809	7
UniProt:P63000 RAC1	6	RAC1 [plasma membrane] (R-HSA-351141) RAC1 [cytosol] (R-HSA-442615) GGC-PalmC-RAC1 [plasma membrane] (R-HSA-2316446) RAC1 [ficolin-1-rich granule membrane] (R-HSA-6804802) RAC1 [secretory granule membrane] (R-HSA-6804770) RAC1 [endoplasmic reticulum membrane] (R-HSA-5672076)	0.684	8
UniProt:Q6SJ93 F111B			0.666	4
UniProt:P17480 UBTF	2	UBTF [nucleoplasm] (R-HSA-73683) p-UBTF [nucleoplasm] (R-HSA-76039)	0.639	4
UniProt:P20226 TBP	1	TBP [nucleoplasm] (R-HSA-83718)	0.632	4
UniProt:Q15572 TAF1C	1	TAF1C [nucleoplasm] (R-HSA-73687)	0.632	4
UniProt:Q12778 FOXO1	5	FOXO1 [nucleoplasm] (R-HSA-199300) p-T24,S256,S319-FOXO1 [nucleoplasm] (R-HSA-199306) p-T24,S256,S319-FOXO1 [cytosol] (R-HSA-211158) Ac-K245,K248,K265-FOXO1 [nucleoplasm] (R-HSA-9626942) p-S218-FOXO1 [nucleoplasm] (R-HSA-5692651)	0.591	5
UniProt:P68400 CSNK2A1	2	CSNK2A1 [cytosol] (R-HSA-201713) CSNK2A1 [nucleoplasm] (R-HSA-6805057)	0.59	2
UniProt:Q7TSY8	1	Sgo2 [cytosol] (R-MMU-376242)	0.564	3
UniProt:P50222 MEOX2			0.556	3
UniProt:O00560 SDCBP	3	SDCBP [cytosol] (R-HSA-373639) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [extracellular region] (R-HSA-6806206)	0.556	3
UniProt:P62750 RPL23A	1	RPL23A [cytosol] (R-HSA-72432)	0.527	2
UniProt:Q562F6 SGO2	1	SGOL2 [cytosol] (R-HSA-376242)	0.527	2
UniProt:Q9NVP1 DDX18			0.527	2
UniProt:Q9BWE0 REPI1			0.527	4
UniProt:P10126	6	Me3K79-EEF1A1 [cytosol] (R-MMU-8932212) Me3K318-EEF1A1 [cytosol] (R-MMU-8932419) EEF1A1 [ficolin-1-rich granule lumen] (R-MMU-6801528) EEF1A1 [extracellular region] (R-MMU-6806456) EEF1A1 [secretory granule lumen] (R-MMU-6801479) EEF1A1 [cytosol] (R-MMU-156905)	0.527	2
UniProt:P10644 PRKAR1A	4	PRKAR1A [cytosol] (R-HSA-57836) PRKAR1A [ciliary base] (R-HSA-5610408) PRKAR1A(1-183)-ALK(1058-1620) fusion [cytosol] (R-HSA-9713471) PRKAR1A(1-183)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9713476)	0.524	2
UniProt:Q15573 TAF1A	1	TAF1A [nucleoplasm] (R-HSA-73689)	0.524	2
UniProt:Q53T94 TAF1B	2	TAF1B [nucleoplasm] (R-HSA-73691) Ac-TAF1B [nucleoplasm] (R-HSA-5138530)	0.524	3
UniProt:P06454 PTMA			0.508	3

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