Reactome | WT1 [nucleoplasm]

WT1 [nucleoplasm]

Stable Identifier

R-HSA-452420

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Wilms tumor protein, WT1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q6N021 TET2

Expand all

External Reference Information

External Reference

UniProt:P19544 WT1

Gene Names

WT1

Chain

chain:1-449

Reference Genes

BioGPS Gene:7490 WT1

COSMIC (genes):WT1 WT1

CTD Gene:7490 WT1

dbSNP Gene:7490 WT1

ENSEMBL:ENSG00000184937 WT1

HGNC:12796 WT1

KEGG:hsa:7490 WT1

Monarch:7490 WT1

NCBI Gene:7490 WT1

OMIM:607102 WT1

UCSC:P19544 WT1

Reference Transcript

Participates

as an input of

as a component of

Cross References

OpenTargets

ENSG00000184937

ENSEMBL

ENSP00000435307, ENSP00000368370, ENST00000452863, ENSG00000184937, ENSP00000492269, ENST00000530998, ENSP00000415516, ENST00000379079, ENST00000639563

HPA

ENSG00000184937-WT1

GeneCards

WT1

PRO

P19544

Pharos - Targets

P19544

Orphanet

WT1

PDB

2PRT, 4WUU, 5KL6, 5KL7, 6B0O, 7BBG, 6B0P, 6B0Q, 4R2E, 6B0R, 4R2P, 1XF7, 2JP9, 4R2Q, 4R2S, 4R2R, 3HPJ, 2JPA, 6RSY, 8ISN, 3MYJ, 6WLH, 5KL2, 6BLW, 5KL3, 5KL4, 5KL5

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q92997 DVL3	4	pp-DVL3 [cytosol] (R-HSA-3772400) p-DVL3 [cytosol] (R-HSA-201680) DVL3 [cytosol] (R-HSA-201678) ub-DVL3 [cytosol] (R-HSA-4652688)	0.668	3
UniProt:Q6A162 KRT40	1	KRT40 [cytosol] (R-HSA-6809605)	0.666	4
UniProt:Q6N021 TET2	1	TET2 [nucleoplasm] (R-HSA-5221011)	0.602	9
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.556	3
IntAct:EBI-10171679 386682			0.488	2

Cite Us!