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DPPA4 [nucleoplasm]
Stable Identifier
R-HSA-452999
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Developmental pluripotency-associated protein 4, DPPA4_HUMAN
Icon
Locations in the PathwayBrowser for interactor UniProt:Q99961 SH3GL1
Expand all
Developmental Biology (Homo sapiens)
Maternal to zygotic transition (MZT) (Homo sapiens)
Zygotic genome activation (ZGA) (Homo sapiens)
DPPA2, DPPA4 and TP53 bind the DUX4 gene cluster (Homo sapiens)
DPPA4 [nucleoplasm] (Homo sapiens)
Transcriptional regulation of pluripotent stem cells (Homo sapiens)
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation (Homo sapiens)
Expression of DPPA4 (Homo sapiens)
DPPA4 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7L190 DPPA4
Gene Names
DPPA4
Chain
chain:1-304
Reference Genes
BioGPS Gene:55211 DPPA4
COSMIC (genes):DPPA4 DPPA4
CTD Gene:55211 DPPA4
dbSNP Gene:55211 DPPA4
ENSEMBL:ENSG00000121570 DPPA4
ENSEMBL_homo_sapiens_GENE:ENSG00000121570.13 DPPA4
HGNC:19200 DPPA4
KEGG Gene (Homo sapiens):55211 DPPA4
Monarch:55211 DPPA4
NCBI Gene:55211 DPPA4
OMIM:614125 DPPA4
UCSC:Q7L190 DPPA4
Reference Transcript
RefSeq:NM_018189.3 DPPA4
Other Identifiers
11736127_s_at
11736128_a_at
11748881_x_at
16957263
219651_PM_at
219651_at
232985_PM_s_at
232985_s_at
2688181
2688182
2688183
2688184
2688185
2688186
2688187
2688189
2688191
2688192
2688193
2688194
2688199
47576_at
47577_at
55211
79675_at
8089448
A_23_P380526
GE55834
GO:0003682
GO:0005515
GO:0005634
GO:0005654
GO:0043226
GO:0048731
GO:0048856
GO:0060484
HMNXSV003047935
Hs.9536.1.S1_3p_a_at
ILMN_1768721
PH_hs_0032640
TC03001638.hg
g8922611_3p_at
Participates
as an output of
Expression of DPPA4 (Homo sapiens)
as an input of
DPPA2, DPPA4 and TP53 bind the DUX4 gene cluster (Homo sapiens)
as a component of
DPPA2:DPPA4:p-S15-TP53:DUX4 gene [nucleoplasm] (Homo sapiens)
Cross References
RefSeq
NP_060659.3
OpenTargets
ENSG00000121570
GeneCards
Q7L190
HPA
ENSG00000121570-DPPA4
Ensembl
ENSP00000335306
,
ENST00000335658
,
ENSG00000121570
PRO
Q7L190
Pharos - Targets
Q7L190
Interactors (36)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q99961 SH3GL1
1
SH3GL1 [cytosol]
(R-HSA-8867732)
0.899
10
UniProt:O95751 LDOC1
0.781
7
UniProt:P46108 CRK
1
CRK [cytosol]
(R-HSA-2980677)
0.666
4
UniProt:Q12161 PSH1
0.61
4
UniProt:Q96KN7 RPGR1
0.556
3
UniProt:Q9C086 INO80B
1
INO80B [nucleoplasm]
(R-HSA-5689599)
0.556
3
UniProt:Q969Y2 GTPBP3
1
GTPBP3 [mitochondrial matrix]
(R-HSA-6787414)
0.556
3
UniProt:Q86X95-2 CIR1
0.556
3
UniProt:Q8IVT2 MISP
0.556
3
IntAct:EBI-22315148 CCSB ORF ID
0.556
3
UniProt:Q96JC9 EAF1
1
EAF1 [nucleoplasm]
(R-HSA-8932787)
0.556
3
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.556
3
UniProt:Q13588 GRAP
1
GRAP [cytosol]
(R-HSA-1433547)
0.556
3
UniProt:Q15025 TNIP1
1
TNIP1 [cytosol]
(R-HSA-5690853)
0.556
3
UniProt:Q14511-2 NEDD9
0.556
3
UniProt:Q6PIV2 FOXR1
0.556
3
UniProt:Q9Y5P6 GMPPB
1
GMPPB [cytosol]
(R-HSA-532525)
0.556
3
UniProt:Q14240-2 EIF4A2
0.556
3
UniProt:Q9UKI8 TLK1
0.556
3
UniProt:Q8WV41 SNX33
0.556
5
UniProt:Q6FGM0 Q6FGM0
0.556
5
UniProt:Q14240 EIF4A2
1
EIF4A2 [cytosol]
(R-HSA-72575)
0.556
3
UniProt:P61326 MAGOH
1
MAGOH [nucleoplasm]
(R-HSA-156658)
0.556
3
UniProt:P38744
1
PCBD1 [cytosol]
(R-SCE-71131)
0.556
3
UniProt:Q5MJ10 SPXN2
0.556
3
UniProt:Q96RF0 SNX18
1
SNX18 [cytosol]
(R-HSA-8868038)
0.556
3
UniProt:Q9H8E8 KAT14
1
KAT14 [nucleoplasm]
(R-HSA-3301917)
0.556
3
UniProt:P05090 APOD
1
APOD [extracellular region]
(R-HSA-5216199)
0.527
2
UniProt:Q9BYJ1 ALOXE3
1
ALOXE3 [cytosol]
(R-HSA-8942204)
0.527
2
UniProt:O75342 ALOX12B
1
ALOX12B [cytosol]
(R-HSA-2142832)
0.527
2
UniProt:Q8NEX9 SDR9C7
1
SDR9C7 [endoplasmic reticulum membrane]
(R-HSA-4084690)
0.527
2
UniProt:Q53EQ6 TIGD5
0.527
2
UniProt:Q9Y5X1 SNX9
3
SNX9 [cytosol]
(R-HSA-8867737)
SNX9 [Golgi membrane]
(R-HSA-432988)
SNX9 [cytoplasmic vesicle membrane]
(R-HSA-432990)
0.527
2
UniProt:Q6SPF0 SAMD1
0.527
2
UniProt:P42357 HAL
1
HAL [cytosol]
(R-HSA-70897)
0.527
3
UniProt:P22735 TGM1
3
TGM1 [cytosol]
(R-HSA-6813756)
TGM1 [cornified envelope]
(R-HSA-8847706)
TGM1 [plasma membrane]
(R-HSA-6813757)
0.527
2
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