RANBP2 SUMOylates RANBP2 with SUMO2

Stable Identifier
R-HSA-4551679
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nuclear envelope, nucleoplasm
ReviewStatus
5/5
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RANBP2 SUMOylates RANBP2 with SUMO2
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RANBP2 SUMOylates RANBP2 at lysine-2652 and lysine-2725 with SUMO2 (Cooper et al. 2005, Hendriks et al. 2014).
Literature References
PubMed ID Title Journal Year
16194093 Fourier transform ion cyclotron resonance mass spectrometry for the analysis of small ubiquitin-like modifier (SUMO) modification: identification of lysines in RanBP2 and SUMO targeted for modification during the E3 autoSUMOylation reaction

Cooper, HJ, Tatham, MH, Jaffray, E, Heath, JK, Lam, TT, Marshall, AG, Hay, RT

Anal. Chem. 2005
25218447 Uncovering global SUMOylation signaling networks in a site-specific manner

Hendriks, IA, D'Souza, RC, Yang, B, Verlaan-de Vries, M, Mann, M, Vertegaal, AC

Nat. Struct. Mol. Biol. 2014
Participants
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Output
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as an event of
Catalyst Activity

SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope]

Physical Entity
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
Activity
SUMO transferase activity (GO:0019789)
Orthologous Events
RANBP2 SUMOylates RANBP2 with SUMO2 (Bos taurus)
RANBP2 SUMOylates RANBP2 with SUMO2 (Drosophila melanogaster)
RANBP2 SUMOylates RANBP2 with SUMO2 (Gallus gallus)
RANBP2 SUMOylates RANBP2 with SUMO2 (Mus musculus)
RANBP2 SUMOylates RANBP2 with SUMO2 (Rattus norvegicus)
RANBP2 SUMOylates RANBP2 with SUMO2 (Sus scrofa)
RANBP2 SUMOylates RANBP2 with SUMO2 (Xenopus tropicalis)
Authored
May, B  (2013-09-13)
Reviewed
Niskanen, E  (2018-05-09)
Niskanen, E  (2018-08-08)
Created
May, B  (2013-09-14)
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