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AcK6-HIST1H2BL [nucleoplasm]
Stable Identifier
R-HSA-4568719
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HATs acetylate histones (Homo sapiens)
EP300 acetylates histone H2A, H2B, H3, H4 (Homo sapiens)
AcK-histone H2A, H2B, H3, H4 [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BL [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BL [nucleoplasm] (Homo sapiens)
HDACs deacetylate histones (Homo sapiens)
HDAC10 deacetylates histone (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BL [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BL [nucleoplasm] (Homo sapiens)
HDAC1:2-containing complex deacetylate histones (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BL [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BL [nucleoplasm] (Homo sapiens)
HDAC3 containing complexes deacetylate histone (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BL [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BL [nucleoplasm] (Homo sapiens)
HDAC8 deacetylates histones (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BL [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BL [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HCMV Infection (Homo sapiens)
HCMV Early Events (Homo sapiens)
Activation of Latent HCMV Genome (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BL [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BL [nucleoplasm] (Homo sapiens)
Delayed Early (DE) Gene Expression (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BL [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BL [nucleoplasm] (Homo sapiens)
Immediate Early (IE) Gene Expression (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BL [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BL [nucleoplasm] (Homo sapiens)
Transcriptional Activation of the HCMV Genome (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BL [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BL [nucleoplasm] (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BL [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BL [nucleoplasm] (Homo sapiens)
HCMV Late Events (Homo sapiens)
Late (L) Gene Expression (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BL [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BL [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99880 H2BC13
Gene Names
H2BC13, H2BFC, HIST1H2BL
Chain
initiator methionine:, chain:2-126
Reference Genes
BioGPS Gene:8340 H2BC13
CTD Gene:8340 H2BC13
dbSNP Gene:8340 H2BC13
ENSEMBL:ENSG00000185130 HIST1H2BL
ENSEMBL_homo_sapiens_GENE:ENSG00000185130.6 H2BC13
HGNC:4748 H2BC13
KEGG Gene (Homo sapiens):8340 H2BC13
Monarch:8340 H2BC13
NCBI Gene:8340 H2BC13
OMIM:602800 H2BC13
UCSC:Q99880 H2BC13
Reference Transcript
RefSeq:NM_003519.3 H2BC13
Other Identifiers
11740828_at
17016486
207611_PM_at
2947033
2947034
2947035
35576_f_at
36347_f_at
8124510
8340
ADDON002867.hg
A_23_P8013
GE511997
GO:0000786
GO:0003677
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005694
GO:0005829
GO:0006325
GO:0006334
GO:0030527
GO:0043226
GO:0043229
GO:0046982
GO:0065003
GO:0070062
HMNXSV003013302
ILMN_1652998
PH_hs_0029201
PH_hs_0031779
TC06001421.hg
g5579460_3p_at
Participates
as a member of
AcK(6,13,16,21)-HIST1H2BL [nucleoplasm] (Homo sapiens)
Other forms of this molecule
Ub-HIST1H2BL [nucleoplasm]
AcK-HIST1H2BL [nucleoplasm]
HIST1H2BL [extracellular region]
AcK13-HIST1H2BL [nucleoplasm]
AcK16-HIST1H2BL [nucleoplasm]
AcK21-HIST1H2BL [nucleoplasm]
Ub-121-HIST1H2BL [nucleoplasm]
HIST1H2BL [nucleoplasm]
Inferred To
H2Bv2 [nucleoplasm]
(Dictyostelium discoideum)
htb1 [nucleoplasm]
(Schizosaccharomyces pombe)
AcK6-HIST1H2BC [nucleoplasm]
(Danio rerio)
Hist1h2bp [nucleoplasm]
(Mus musculus)
HIST1H2B5L [nucleoplasm]
(Gallus gallus)
H2B-V [nucleoplasm]
(Gallus gallus)
H2Bv3 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VII [nucleoplasm]
(Gallus gallus)
Homologues of AcK6-HIST1H2BC [nucleoplasm]
(Danio rerio)
Homologues of AcK6-HIST1H2BC [nucleoplasm]
(Gallus gallus)
Homologues of AcK6-HIST1H2BC [nucleoplasm]
(Xenopus tropicalis)
H2B-I [nucleoplasm]
(Gallus gallus)
Homologues of AcK6-HIST1H2BL [nucleoplasm]
(Mus musculus)
H2bc3 [nucleoplasm]
(Mus musculus)
HTB2 [nucleoplasm]
(Saccharomyces cerevisiae)
H2Bv1 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VIII [nucleoplasm]
(Gallus gallus)
His2B [nucleoplasm]
(Drosophila melanogaster)
AcK6-HIST1H2BB [nucleoplasm]
(Plasmodium falciparum)
H2bc7 [nucleoplasm]
(Mus musculus)
AcK6-HIST1H2BL [nucleoplasm]
(Bos taurus)
h2bc11 [nucleoplasm]
(Xenopus tropicalis)
si:ch211-113a14.29 [nucleoplasm]
(Danio rerio)
Homologues of AcK6-HIST1H2BB [nucleoplasm]
(Dictyostelium discoideum)
Homologues of AcK6-HIST1H2BB [nucleoplasm]
(Plasmodium falciparum)
Homologues of AcK6-HIST1H2BB [nucleoplasm]
(Saccharomyces cerevisiae)
LOC100498553 [nucleoplasm]
(Xenopus tropicalis)
LOC116411635 [nucleoplasm]
(Xenopus tropicalis)
hist2h2l [nucleoplasm]
(Danio rerio)
HTB1 [nucleoplasm]
(Saccharomyces cerevisiae)
LOC570661 [nucleoplasm]
(Danio rerio)
H1-2 [nucleoplasm]
(Sus scrofa)
h2bc21 [nucleoplasm]
(Xenopus tropicalis)
Modified Residues
Name
N6-acetyl-L-lysine at 6
Coordinate
6
PsiMod Name
N6-acetyl-L-lysine [MOD:00064]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.
Cross References
RefSeq
NP_003510.1
OpenTargets
ENSG00000185130
HPA
ENSG00000185130-H2BC13
GeneCards
Q99880
Ensembl
ENST00000377401
,
ENSP00000366618
,
ENSG00000185130
PRO
Q99880
Pharos - Targets
Q99880
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96CW1 AP2M1
6
AP2M1 [plasma membrane]
(R-HSA-167585)
AP2M1 [lysosomal membrane]
(R-HSA-196144)
AP2M1 [cytosol]
(R-HSA-182227)
AP2M1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-2130423)
AP2M1 [endolysosome membrane]
(R-HSA-6784828)
p-T156 AP2M1 [cytosol]
(R-HSA-8856805)
0.556
3
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