Reactome | AcK16-HIST2H2BF [nucleoplasm]

AcK16-HIST2H2BF [nucleoplasm]

Stable Identifier

R-HSA-4568725

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - HCMV Infection (Homo sapiens)
      - HCMV Early Events (Homo sapiens)
        
        Activation of Latent HCMV Genome (Homo sapiens)
        
        Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
        
        Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-HIST2H2BF [nucleoplasm] (Homo sapiens)
        
        AcK16-HIST2H2BF [nucleoplasm] (Homo sapiens)
        
        Delayed Early (DE) Gene Expression (Homo sapiens)
        
        Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
        
        Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-HIST2H2BF [nucleoplasm] (Homo sapiens)
        
        AcK16-HIST2H2BF [nucleoplasm] (Homo sapiens)
        
        Immediate Early (IE) Gene Expression (Homo sapiens)
        
        Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
        
        Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-HIST2H2BF [nucleoplasm] (Homo sapiens)
        
        AcK16-HIST2H2BF [nucleoplasm] (Homo sapiens)
        
        Transcriptional Activation of the HCMV Genome (Homo sapiens)
        
        Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-HIST2H2BF [nucleoplasm] (Homo sapiens)
        
        AcK16-HIST2H2BF [nucleoplasm] (Homo sapiens)
        
        Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
        
        Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-HIST2H2BF [nucleoplasm] (Homo sapiens)
        
        AcK16-HIST2H2BF [nucleoplasm] (Homo sapiens)
      - HCMV Late Events (Homo sapiens)
        
        Late (L) Gene Expression (Homo sapiens)
        
        Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
        
        Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-HIST2H2BF [nucleoplasm] (Homo sapiens)
        
        AcK16-HIST2H2BF [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q5QNW6 H2BC18

Gene Names

H2BC18, HIST2H2BF

Chain

initiator methionine:1, chain:2-126

Reference Genes

BioGPS Gene:440689 H2BC18

CTD Gene:440689 H2BC18

dbSNP Gene:440689 H2BC18

ENSEMBL:ENSG00000203814 HIST2H2BF

ENSEMBL:ENSG00000203814.7 H2BC18

HGNC:24700 H2BC18

KEGG Gene (Homo sapiens):440689 H2BC18

Monarch:440689 H2BC18

NCBI Gene:440689 H2BC18

UCSC:Q5QNW6 H2BC18

Reference Transcript

Other Identifiers

11750018_at

2434032

2434045

2434046

2434100

2434127

2459531

440689

GO:0000786

GO:0003674

GO:0003677

GO:0005198

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005694

GO:0005829

GO:0030527

GO:0043226

GO:0043229

GO:0046982

GO:0070062

HMNXSV003002158

HMNXSV003017461

p33351

Participates

as a member of

AcK(6,13,16,21)-HIST2H2BF [nucleoplasm] (Homo sapiens)

Other forms of this molecule

Ub-HIST2H2BF [nucleoplasm]

AcK-HIST2H2BF [nucleoplasm]

HIST2H2BF [nucleoplasm]

AcK21-HIST2H2BF [nucleoplasm]

AcK6-HIST2H2BF [nucleoplasm]

AcK13-HIST2H2BF [nucleoplasm]

Inferred To

H2B-VIII [nucleoplasm] (Gallus gallus)

His2B [nucleoplasm] (Drosophila melanogaster)

h2bc14 [nucleoplasm] (Xenopus tropicalis)

AcK16-HIST1H2BB [nucleoplasm] (Danio rerio)

AcK16-HIST1H2BC [nucleoplasm] (Danio rerio)

AcK16-HIST1H2BC [nucleoplasm] (Xenopus tropicalis)

si:ch211-113a14.29 [nucleoplasm] (Danio rerio)

HIST1H2B5L [nucleoplasm] (Gallus gallus)

H2B-V [nucleoplasm] (Gallus gallus)

LOC100498553 [nucleoplasm] (Xenopus tropicalis)

AcK16-HIST2H2BF [nucleoplasm] (Canis familiaris)

LOC116411635 [nucleoplasm] (Xenopus tropicalis)

H2B-VII [nucleoplasm] (Gallus gallus)

H2B-I [nucleoplasm] (Gallus gallus)

H2BC5 [nucleoplasm] (Bos taurus)

hist2h2l [nucleoplasm] (Danio rerio)

LOC426037 [nucleoplasm] (Gallus gallus)

Homologues of AcK16-HIST1H2BC [nucleoplasm] (Danio rerio)

Homologues of AcK16-HIST1H2BC [nucleoplasm] (Gallus gallus)

Homologues of AcK16-HIST1H2BC [nucleoplasm] (Xenopus tropicalis)

LOC570661 [nucleoplasm] (Danio rerio)

h2bc21 [nucleoplasm] (Xenopus tropicalis)

Modified Residues

Name

N6-acetyl-L-lysine at 16

Coordinate

PsiMod Name

N6-acetyl-L-lysine [MOD:00064]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.

Cross References

RefSeq

NP_001019770.1, NP_001154806.1

OpenTargets

ENSG00000203814

HPA

ENSG00000203814-H2BC18

GeneCards

Q5QNW6

Ensembl

ENSP00000358164, ENST00000545683, ENST00000369167, ENSP00000445831, ENSG00000203814

PRO

Q5QNW6

Pharos - Targets

Q5QNW6

PDB

6MUP, 6MUO