Reactome | SUMOylation of NOP58 with SUMO1

SUMOylation of NOP58 with SUMO1

Stable Identifier

R-HSA-4570467

Type

Reaction [transition]

Species

Homo sapiens

Compartment

nucleoplasm

ReviewStatus

5/5

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NOP58 (NOP5) is SUMOylated at lysine-467 and lysine-497 with SUMO1 (Matafora et al. 2009, Westman et al. 2010, Westman and Lamond 2011,Impens et al. 2014). SUMOylation is required for binding of snoRNAs by NOP58.

Literature References

PubMed ID	Title	Journal	Year
19596686	Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition Blasi, F, Mori, S, Bachi, A, Matafora, V, D'Amato, A	Mol. Cell Proteomics	2009
12196509	Proteomic analysis of the mammalian nuclear pore complex Matunis, MJ, Cronshaw, JM, Chait, BT, Zhang, W, Krutchinsky, AN	J Cell Biol	2002
20797632	A proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58 Lam, YW, Lamond, AI, Bertrand, E, Westman, BJ, Verheggen, C, Hutten, S	Mol. Cell	2010
25114211	Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli Impens, F, Cossart, P, Radoshevich, L, Ribet, D	Proc. Natl. Acad. Sci. U.S.A.	2014
21647297	A role for SUMOylation in snoRNP biogenesis revealed by quantitative proteomics Lamond, AI, Westman, BJ	Nucleus	2011