SUMOylation of Histone H4 with SUMO3

Stable Identifier
R-HSA-4570485
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
SUMOylation of Histone H4 with SUMO3
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Histone H4 (HIST1H4) is SUMOylated at an unknown residue with SUMO3 (Shiio and Eisenman 2003). SUMOylation of histone H4 is associated with repression of transcription.
Literature References
PubMed ID Title Journal Year
14578449 Histone sumoylation is associated with transcriptional repression

Eisenman, RN, Shiio, Y

Proc. Natl. Acad. Sci. U.S.A. 2003
Participants
Input
Output
Participates
as an event of
Catalyst Activity

SUMO transferase activity of SUMO3:UBE2I [nucleoplasm]

Physical Entity
SUMO3:UBE2I [nucleoplasm] (Homo sapiens)
Activity
SUMO transferase activity (GO:0019789)
Orthologous Events
SUMOylation of Histone H4 with SUMO3 (Bos taurus)
SUMOylation of Histone H4 with SUMO3 (Danio rerio)
SUMOylation of Histone H4 with SUMO3 (Dictyostelium discoideum)
SUMOylation of Histone H4 with SUMO3 (Drosophila melanogaster)
SUMOylation of Histone H4 with SUMO3 (Gallus gallus)
SUMOylation of Histone H4 with SUMO3 (Mus musculus)
SUMOylation of Histone H4 with SUMO3 (Plasmodium falciparum)
SUMOylation of Histone H4 with SUMO3 (Rattus norvegicus)
SUMOylation of Histone H4 with SUMO3 (Sus scrofa)
Authored
May, B  (2013-09-19)
Reviewed
Matunis, MJ  (2017-01-22)
Yang, WC  (2017-01-22)
Lu, J  (2017-01-22)
Created
May, B  (2013-09-21)
Cite Us!