SUMOylation of XPC with SUMO1

Stable Identifier
R-HSA-4570528
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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General
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XPC is SUMOylated at lysine-655 with SUMO1 (Wang et al. 2005, 2007). SUMOylation occurs after UV irradiation and may target XPC for destruction (Wang et al. 2007).
Literature References
PubMed ID Title Journal Year
16030353 DNA repair factor XPC is modified by SUMO-1 and ubiquitin following UV irradiation

Wang, QE, El-Mahdy, MA, Zhu, Q, Li, J, Wani, G, Wani, AA

Nucleic Acids Res. 2005
17693435 Ubiquitylation-independent degradation of Xeroderma pigmentosum group C protein is required for efficient nucleotide excision repair

Wang, QE, Qin, S, El-Mahdy, MA, Zhu, Q, Patnaik, S, Wani, G, Zhao, Q, Wani, AA, Praetorius-Ibba, M

Nucleic Acids Res. 2007
Participants
Participates
Catalyst Activity

SUMO transferase activity of SUMO1:C93-UBE2I [cytoplasm]

Orthologous Events
Authored
Reviewed
Created
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