Reactome | SATB2 [nucleoplasm]

SATB2 [nucleoplasm]

Stable Identifier

R-HSA-4615944

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DNA-binding protein SATB2, SATB2_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q01826 SATB1

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional regulation by RUNX2 (Homo sapiens)
      - RUNX2 regulates bone development (Homo sapiens)
        
        RUNX2 regulates osteoblast differentiation (Homo sapiens)
        
        RUNX2 binds to SATB2 (Homo sapiens)
        
        SATB2 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UPW6 SATB2

Gene Names

SATB2, KIAA1034

Chain

chain:1-733

Reference Genes

BioGPS Gene:23314 SATB2

COSMIC (genes):SATB2 SATB2

CTD Gene:23314 SATB2

dbSNP Gene:23314 SATB2

ENSEMBL:ENSG00000119042 SATB2

ENSEMBL_homo_sapiens_GENE:ENSG00000119042.18 SATB2

HGNC:21637 SATB2

KEGG Gene (Homo sapiens):23314 SATB2

Monarch:23314 SATB2

NCBI Gene:23314 SATB2

OMIM:608148 SATB2

UCSC:Q9UPW6 SATB2

Reference Transcript

Other Identifiers

11728904_a_at

11728905_at

11728906_s_at

11755392_a_at

16907044

213435_PM_at

213435_at

23314

2594097

2594098

2594099

2594100

2594101

2594102

2594103

2594109

2594118

2594119

2594120

2594123

2594129

2594134

2594136

2594137

2594138

2594153

2594163

2594164

2594166

2594167

2594168

2594169

2594170

2594171

2594172

2594173

2594174

2594175

2594176

2594185

2594197

2594198

2594199

41708_at

8058091

A_32_P174365

GE53705

GO:0000118

GO:0000122

GO:0000785

GO:0000977

GO:0000978

GO:0000981

GO:0001228

GO:0001764

GO:0002076

GO:0003677

GO:0003682

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005667

GO:0005694

GO:0006325

GO:0006338

GO:0006351

GO:0006355

GO:0006357

GO:0009880

GO:0010468

GO:0016363

GO:0030154

GO:0042826

GO:0043226

GO:0043565

GO:0045944

GO:0048704

GO:0048856

GO:0048870

GO:0051216

GO:0060021

GO:0071310

GO:0140110

HMNXSV003014217

Hs.12896.0.S1_3p_at

ILMN_1738657

PH_hs_0030098

TC02002656.hg

Participates

as an input of

as a component of

RUNX2:SATB2 [nucleoplasm] (Homo sapiens)

Other forms of this molecule

polySUMO3-K233,K350-SATB2 [nucleoplasm]

Inferred To

dve-1 [nucleoplasm] (Caenorhabditis elegans)

SATB2 [nucleoplasm] (Bos taurus)

SATB2 [nucleoplasm] (Canis familiaris)

SATB2 [nucleoplasm] (Gallus gallus)

SATB2 [nucleoplasm] (Sus scrofa)

satb2 [nucleoplasm] (Xenopus tropicalis)

dve [nucleoplasm] (Drosophila melanogaster)

Satb2 [nucleoplasm] (Mus musculus)

Satb2 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001165980.1, XP_006712435.1, NP_056080.1, XP_011509142.1, NP_001165988.1

OpenTargets

ENSG00000119042

GeneCards

Q9UPW6

HPA

ENSG00000119042-SATB2

Ensembl

ENSP00000514854, ENSP00000388581, ENSP00000514853, ENST00000417098, ENSG00000119042, ENSP00000401112, ENST00000260926, ENSP00000405420, ENSP00000260926, ENST00000457245, ENST00000428695, ENST00000700191, ENST00000700193

PRO

Q9UPW6

Pharos - Targets

Q9UPW6

Orphanet

16802

PDB

1WIZ, 1WI3, 2CSF

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P53350 PLK1	4	PLK1 [nucleoplasm] (R-HSA-156720) p-T210-PLK1 [cytosol] (R-HSA-3000318) p-T210-PLK1 [nucleoplasm] (R-HSA-3002800) PLK1 [cytosol] (R-HSA-164603)	0.643	3
UniProt:Q9H3D4-2 TP63			0.556	5
UniProt:Q8TBN0 RAB3IL1	1	RAB3IL1 [cytosol] (R-HSA-8875296)	0.556	3
UniProt:Q9H1A7 RPB1C			0.556	3
UniProt:Q96LI6 HSFY1			0.527	2
UniProt:Q6ZWI9 RFPLB			0.527	2
UniProt:Q01826 SATB1	5	polySUMO2,3-K744-SATB1 [nucleoplasm] (R-HSA-4615978) monoSUMO1-K744-SATB1 [nucleoplasm] (R-HSA-4615954) SATB1(255-763) [nucleoplasm] (R-HSA-352264) SATB1(1-254) [nucleoplasm] (R-HSA-352269) SATB1 [nucleoplasm] (R-HSA-201593)	0.527	3
UniProt:Q9Y2M5 KLHL20	1	KLHL20 [cytosol] (R-HSA-976032)	0.527	2
UniProt:P43363 MAGAA			0.527	2
UniProt:Q5SZD1 CF141			0.527	2
UniProt:Q15014 MORF4L2	1	MORF4L2 [nucleoplasm] (R-HSA-3322945)	0.527	2
UniProt:Q96LD4 TRI47			0.527	3
UniProt:Q15274 QPRT	1	QPRT [cytosol] (R-HSA-197212)	0.527	3
UniProt:Q12946 FOXF1	1	FOXF1 [nucleoplasm] (R-HSA-9759879)	0.527	2
UniProt:Q12952 FOXL1			0.483	2
UniProt:Q9H3D4 TP63	1	TP63 [nucleoplasm] (R-HSA-2997585)	0.463	2