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SATB2 [nucleoplasm]
Stable Identifier
R-HSA-4615944
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DNA-binding protein SATB2, SATB2_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q15014 MORF4L2
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX2 (Homo sapiens)
RUNX2 regulates bone development (Homo sapiens)
RUNX2 regulates osteoblast differentiation (Homo sapiens)
RUNX2 binds to SATB2 (Homo sapiens)
SATB2 [nucleoplasm] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
SUMOylation of chromatin organization proteins (Homo sapiens)
PIAS1 SUMOylates SATB2 with SUMO3 (Homo sapiens)
SATB2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UPW6 SATB2
Gene Names
SATB2, KIAA1034
Chain
chain:1-733
Reference Genes
BioGPS Gene:23314 SATB2
COSMIC (genes):SATB2 SATB2
CTD Gene:23314 SATB2
dbSNP Gene:23314 SATB2
ENSEMBL:ENSG00000119042 SATB2
ENSEMBL_homo_sapiens_GENE:ENSG00000119042.18 SATB2
HGNC:21637 SATB2
KEGG Gene (Homo sapiens):23314 SATB2
Monarch:23314 SATB2
NCBI Gene:23314 SATB2
OMIM:608148 SATB2
UCSC:Q9UPW6 SATB2
Reference Transcript
RefSeq:NM_001172509.1 SATB2
RefSeq:NM_015265.3 SATB2
RefSeq:NM_001172517.1 SATB2
RefSeq:XM_011510840.2 SATB2
RefSeq:XM_006712372.2 SATB2
Other Identifiers
11728904_a_at
11728905_at
11728906_s_at
11755392_a_at
16907044
213435_PM_at
213435_at
23314
2594097
2594098
2594099
2594100
2594101
2594102
2594103
2594109
2594118
2594119
2594120
2594123
2594129
2594134
2594136
2594137
2594138
2594153
2594163
2594164
2594166
2594167
2594168
2594169
2594170
2594171
2594172
2594173
2594174
2594175
2594176
2594185
2594197
2594198
2594199
41708_at
8058091
A_32_P174365
GE53705
GO:0000118
GO:0000122
GO:0000785
GO:0000977
GO:0000978
GO:0000981
GO:0001228
GO:0001764
GO:0002076
GO:0003677
GO:0003682
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0006357
GO:0009880
GO:0010468
GO:0016363
GO:0030154
GO:0042826
GO:0043226
GO:0043565
GO:0045944
GO:0048704
GO:0048856
GO:0048870
GO:0051216
GO:0060021
GO:0071310
GO:0140110
HMNXSV003014217
Hs.12896.0.S1_3p_at
ILMN_1738657
PH_hs_0030098
TC02002656.hg
Participates
as an input of
PIAS1 SUMOylates SATB2 with SUMO3 (Homo sapiens)
RUNX2 binds to SATB2 (Homo sapiens)
as a component of
RUNX2:SATB2 [nucleoplasm] (Homo sapiens)
Other forms of this molecule
polySUMO3-K233,K350-SATB2 [nucleoplasm]
Inferred To
dve-1 [nucleoplasm]
(Caenorhabditis elegans)
SATB2 [nucleoplasm]
(Bos taurus)
SATB2 [nucleoplasm]
(Canis familiaris)
SATB2 [nucleoplasm]
(Gallus gallus)
SATB2 [nucleoplasm]
(Sus scrofa)
satb2 [nucleoplasm]
(Xenopus tropicalis)
dve [nucleoplasm]
(Drosophila melanogaster)
Satb2 [nucleoplasm]
(Mus musculus)
Satb2 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_001165980.1
,
XP_006712435.1
,
NP_056080.1
,
XP_011509142.1
,
NP_001165988.1
OpenTargets
ENSG00000119042
GeneCards
Q9UPW6
HPA
ENSG00000119042-SATB2
Ensembl
ENSP00000514854
,
ENSP00000388581
,
ENSP00000514853
,
ENST00000417098
,
ENSG00000119042
,
ENSP00000401112
,
ENST00000260926
,
ENSP00000405420
,
ENSP00000260926
,
ENST00000457245
,
ENST00000428695
,
ENST00000700191
,
ENST00000700193
PRO
Q9UPW6
Pharos - Targets
Q9UPW6
Orphanet
16802
PDB
1WIZ
,
1WI3
,
2CSF
Interactors (16)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P53350 PLK1
4
PLK1 [nucleoplasm]
(R-HSA-156720)
p-T210-PLK1 [cytosol]
(R-HSA-3000318)
p-T210-PLK1 [nucleoplasm]
(R-HSA-3002800)
PLK1 [cytosol]
(R-HSA-164603)
0.643
3
UniProt:Q9H3D4-2 TP63
0.556
5
UniProt:Q8TBN0 RAB3IL1
1
RAB3IL1 [cytosol]
(R-HSA-8875296)
0.556
3
UniProt:Q9H1A7 RPB1C
0.556
3
UniProt:Q96LI6 HSFY1
0.527
2
UniProt:Q6ZWI9 RFPLB
0.527
2
UniProt:Q01826 SATB1
5
polySUMO2,3-K744-SATB1 [nucleoplasm]
(R-HSA-4615978)
monoSUMO1-K744-SATB1 [nucleoplasm]
(R-HSA-4615954)
SATB1(255-763) [nucleoplasm]
(R-HSA-352264)
SATB1(1-254) [nucleoplasm]
(R-HSA-352269)
SATB1 [nucleoplasm]
(R-HSA-201593)
0.527
3
UniProt:Q9Y2M5 KLHL20
1
KLHL20 [cytosol]
(R-HSA-976032)
0.527
2
UniProt:P43363 MAGAA
0.527
2
UniProt:Q5SZD1 CF141
0.527
2
UniProt:Q15014 MORF4L2
1
MORF4L2 [nucleoplasm]
(R-HSA-3322945)
0.527
2
UniProt:Q96LD4 TRI47
0.527
3
UniProt:Q15274 QPRT
1
QPRT [cytosol]
(R-HSA-197212)
0.527
3
UniProt:Q12946 FOXF1
1
FOXF1 [nucleoplasm]
(R-HSA-9759879)
0.527
2
UniProt:Q12952 FOXL1
0.483
2
UniProt:Q9H3D4 TP63
1
TP63 [nucleoplasm]
(R-HSA-2997585)
0.463
2
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