Reactome | monoSUMO1-K744-SATB1 [nucleoplasm]

monoSUMO1-K744-SATB1 [nucleoplasm]

Stable Identifier

R-HSA-4615954

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DNA-binding protein SATB1, SATB1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q01826 SATB1

Gene Names

SATB1

Chain

chain:1-763

Reference Genes

BioGPS Gene:6304 SATB1

COSMIC (genes):SATB1 SATB1

CTD Gene:6304 SATB1

dbSNP Gene:6304 SATB1

ENSEMBL:ENSG00000182568 SATB1

HGNC:10541 SATB1

KEGG:hsa:6304 SATB1

Monarch:6304 SATB1

NCBI Gene:6304 SATB1

OMIM:602075 SATB1

UCSC:Q01826 SATB1

Reference Transcript

Other Identifiers

11741058_a_at

11741059_s_at

11754725_x_at

16951409

203408_PM_s_at

203408_s_at

241365_PM_at

241365_at

2665197

2665198

2665200

2665201

2665202

2665203

2665204

2665205

2665206

2665207

2665208

2665209

2665210

2665223

2665225

2665227

2665231

2665232

2665233

2665236

2665237

2665238

2665239

2665240

2665241

2665242

2665243

2665248

2665249

2665250

2665251

2665252

2665253

2665254

2665256

2665257

2665258

2665259

2665260

2665261

2665266

2665267

2665269

2665270

2665307

2665314

2665315

35667_at

36899_at

46768_r_at

53365_f_at

6304

73870_at

8085716

87288_at

A_23_P259741

GE624984

GE78977

GO:0000122

GO:0000785

GO:0000977

GO:0000978

GO:0000981

GO:0001227

GO:0003677

GO:0003690

GO:0005515

GO:0005634

GO:0005654

GO:0006325

GO:0006338

GO:0006355

GO:0006357

GO:0016363

GO:0016604

GO:0016605

GO:0043226

GO:0043565

GO:0140110

HMNXSV003010099

HMNXSV003048348

Hs.33024.0.A1_3p_at

ILMN_1690646

ILMN_1882495

M97287_at

PH_hs_0002783

PH_hs_0040811

TC03003338.hg

U33920_at

g4506790_3p_a_at

g4759089_3p_at

Participates

as an output of

PIAS1 SUMOylates SATB1 with SUMO1 (Homo sapiens)

Other forms of this molecule

SATB1 [nucleoplasm]

SATB1(1-254) [nucleoplasm]

SATB1(255-763) [nucleoplasm]

polySUMO2,3-K744-SATB1 [nucleoplasm]

Inferred To

dve-1 [nucleoplasm] (Caenorhabditis elegans)

Satb1 [nucleoplasm] (Rattus norvegicus)

monoSUMO1-K744-SATB1 [nucleoplasm] (Mus musculus)

satb1a [nucleoplasm] (Danio rerio)

SATB1 [nucleoplasm] (Bos taurus)

SATB1 [nucleoplasm] (Gallus gallus)

SATB1 [nucleoplasm] (Sus scrofa)

satb1 [nucleoplasm] (Xenopus tropicalis)

Modified Residues

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 744

Coordinate

744

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

XP_011532291.1, NP_001309800.1, NP_001309801.1, NP_002962.1, NP_001309802.1, XP_011532290.1, NP_001309803.1, NP_001182399.1, NP_001309804.1, NP_001124482.1

ENSEMBL

ENST00000415069, ENSP00000398072, ENSP00000514845, ENSP00000514846, ENSP00000399708, ENST00000700180, ENSP00000514847, ENST00000457005, ENSP00000514848, ENST00000700178, ENST00000700177, ENSP00000341024, ENST00000417717, ENSP00000390529, ENST00000700179, ENST00000454909, ENSP00000399518, ENST00000338745

OpenTargets

ENSG00000182568

HPA

ENSG00000182568-SATB1

PRO

Q01826

Pharos - Targets

Q01826

GlyGen

Q01826

Orphanet

SATB1

PDB

6LFF, 1YSE, 3TUO, 2O4A, 2MW8, 2L1P, 3NZL, 2O49

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P35222 CTNNB1	20	CTNNB1 S45A [cytosol] (R-HSA-9663982) CTNNB1 S45F [cytosol] (R-HSA-4791268) CTNNB1 S45C [cytosol] (R-HSA-9663983) CTNNB1 S45Y [cytosol] (R-HSA-9663975) CTNNB1 S45N [cytosol] (R-HSA-9663984) CTNNB1 S45P [cytosol] (R-HSA-4791272) pT41,S45-CTNNB1 S37P [cytosol] (R-HSA-9663981) pT41,S45-CTNNB1 S37F [cytosol] (R-HSA-4839621) CTNNB1 [nucleoplasm] (R-HSA-3451168) CTNNB1 [cytosol] (R-HSA-448839) CTNNB1(1-115) [cytosol] (R-HSA-202930) CTNNB1(116-376) [cytosol] (R-HSA-202950) CTNNB1 [plasma membrane] (R-HSA-9038440) p-S33,S37,T41,S45 CTNNB1 [cytosol] (R-HSA-8942374) p-S37,T41,S45, CTNNB1 [cytosol] (R-HSA-8942369) p-T41,S45 CTNNB1 [cytosol] (R-HSA-8942367) p-S45 CTNNB1 [cytosol] (R-HSA-8942363) p-S552-CTNNB1 [cytosol] (R-HSA-3134933) p-S552-CTNNB1 [nucleoplasm] (R-HSA-3134926) p-Y-CTNNB1 [cytosol] (R-HSA-8876940)	0.66	9
UniProt:Q6FHY5 Q6FHY5			0.556	3
UniProt:G2XKQ0 SUMO5			0.556	3
UniProt:Q9NZD8 SPG21			0.556	3
UniProt:P63279 UBE2I	9	monoSUMO1-K14-UBE2I [nucleoplasm] (R-HSA-4085358) UBE2I [nuclear envelope] (R-HSA-4655408) SUMO2-C93-UBE2I [cytosol] (R-HSA-4656944) SUMO3-C93-UBE2I [nucleoplasm] (R-HSA-3730629) UBE2I [nucleoplasm] (R-HSA-912481) SUMO1-C93-UBE2I [nucleoplasm] (R-HSA-3730617) SUMO2-C93-UBE2I [nucleoplasm] (R-HSA-3730619) SUMO1-C93-UBE2I [cytosol] (R-HSA-4656909) UBE2I [cytosol] (R-HSA-4655342)	0.553	2
UniProt:Q9UPW6 SATB2	2	SATB2 [nucleoplasm] (R-HSA-4615944) polySUMO3-K233,K350-SATB2 [nucleoplasm] (R-HSA-4615865)	0.527	3
UniProt:Q96LD4 TRI47			0.527	3
UniProt:P63165 SUMO1	11	lysyl-G97-SUMO1 [nucleoplasm] (R-HSA-9761562) SUMO1(2-101) [nucleoplasm] (R-HSA-2990831) SUMO1 [nucleoplasm] (R-HSA-877304) UBA2-G97-SUMO1 [nucleoplasm] (R-HSA-3730616) UBE2I-G97-SUMO1 [nucleoplasm] (R-HSA-3730622) lysyl-G97-SUMO1 [cytosol] (R-HSA-9762266) lysyl-G97-SUMO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9762380) UBE2I-G97-SUMO1 [cytosol] (R-HSA-4656941) lysyl-G97-SUMO1 [viral capsid] (R-HSA-9762386) lysyl-G97-SUMO1 [nucleolus] (R-HSA-9762385) lysyl-G97-SUMO1 [plasma membrane] (R-HSA-9762382)	0.508	2
UniProt:Q13627 DYRK1A	1	DYRK1A [nucleoplasm] (R-HSA-1362267)	0.499	2
UniProt:Q12952 FOXL1			0.483	2

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