SUMOyation of DNMT1 with SUMO1

Stable Identifier
R-HSA-4655431
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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DNMT1 is SUMOyated at several unknown lysine residues with SUMO1 (Lee et al. 2009). SUMOylation increases the DNA methyltransferase activity of DNMT1.
Literature References
PubMed ID Title Journal Year
19450230 SUMOylation enhances DNA methyltransferase 1 activity

Lee, B, Muller, MT

Biochem. J. 2009
Participants
Participates
Catalyst Activity

SUMO transferase activity of SUMO1:C93-UBE2I [cytoplasm]

Orthologous Events
Authored
Reviewed
Created
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