PIAS2,3,4 SUMOylate RORA with SUMO1

Stable Identifier
R-HSA-4719436
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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PIAS2-2 (PIASx-alpha), PIAS3, and PIAS4 SUMOylate RORA with SUMO1 at lysine-240 (Hwang et al. 2009). SUMOylation increases transcriptional activation by RORA.
Literature References
PubMed ID Title Journal Year
19041634 SUMOylation of RORalpha potentiates transcriptional activation function

Kim, KI, Park, JH, Yang, Y, Hwang, EJ, Baek, SH, Lee, JM, Lim, JS, Kim, JH, Jeong, J

Biochem. Biophys. Res. Commun. 2009
Participants
Participates
Catalyst Activity

SUMO transferase activity of PIAS2-2,PIAS3,PIAS4 [nucleoplasm]

Orthologous Events
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Reviewed
Created
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