Reactome | JMJD6 [nucleoplasm]

JMJD6 [nucleoplasm]

Stable Identifier

R-HSA-4754226

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

JMJD6_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6NYC1 JMJD6

Gene Names

JMJD6, KIAA0585, PSR, PTDSR

Chain

chain:1-403

Reference Genes

BioGPS Gene:23210 JMJD6

COSMIC (genes):JMJD6 JMJD6

CTD Gene:23210 JMJD6

dbSNP Gene:23210 JMJD6

ENSEMBL:ENSG00000070495 JMJD6

HGNC:19355 JMJD6

Monarch:23210 JMJD6

NCBI Gene:23210 JMJD6

OMIM:604914 JMJD6

UCSC:Q6NYC1 JMJD6

Reference Transcript

Other Identifiers

11736069_at

11744289_a_at

1552629_PM_a_at

1552629_a_at

16849308

212722_PM_s_at

212722_s_at

212723_PM_at

212723_at

215233_PM_at

215233_at

23210

2583901

2583902

35849_at

35850_at

35851_g_at

3771768

3771769

3771770

3771771

3771772

3771774

3771775

3771777

3771778

3771779

3771781

3771782

3771783

3771784

3771786

3771788

3771789

3771790

3771791

3771794

3771795

8018793

A_23_P311616

GE53294

GE538317

GO:0001568

GO:0001822

GO:0002040

GO:0002376

GO:0003723

GO:0003727

GO:0003824

GO:0005506

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005829

GO:0005886

GO:0006325

GO:0006338

GO:0006355

GO:0006397

GO:0006909

GO:0007166

GO:0007507

GO:0008380

GO:0016071

GO:0016192

GO:0016491

GO:0018395

GO:0030154

GO:0030324

GO:0032452

GO:0032463

GO:0033077

GO:0033746

GO:0033749

GO:0035513

GO:0035515

GO:0038023

GO:0042116

GO:0042802

GO:0043226

GO:0043277

GO:0043654

GO:0045893

GO:0045944

GO:0046872

GO:0048024

GO:0048821

GO:0048856

GO:0051213

GO:0051260

GO:0060041

GO:0060089

GO:0065003

GO:0070815

GO:0098772

GO:0106140

GO:0140096

GO:0140098

GO:0140457

GO:0140537

GO:0140694

GO:1990904

HMNXSV003032017

HMNXSV003034192

Hs.72660.0.S1_3p_at

Hs.72660.1.S1_3p_at

Hs2.72660.1.S1_3p_s_at

ILMN_1666068

ILMN_2412024

PH_hs_0004179

TC17001907.hg

Participates

as a component of

JMJD6:Fe2+ [nucleoplasm] (Homo sapiens)

Inferred To

JMJD6 [nucleoplasm] (Bos taurus)

JMJD6 [nucleoplasm] (Caenorhabditis elegans)

JMJD6 [nucleoplasm] (Canis familiaris)

JMJD6 [nucleoplasm] (Danio rerio)

JMJD6 [nucleoplasm] (Drosophila melanogaster)

JMJD6 [nucleoplasm] (Gallus gallus)

JMJD6 [nucleoplasm] (Mus musculus)

JMJD6 [nucleoplasm] (Rattus norvegicus)

JMJD6 [nucleoplasm] (Sus scrofa)

jmjd6 [nucleoplasm] (Xenopus tropicalis)

Cross References

Guide to Pharmacology - Targets

2892

OpenTargets

ENSG00000070495

ENSEMBL

ENST00000397625, ENSP00000394085, ENST00000445478, ENSP00000380750

HPA

ENSG00000070495-JMJD6

PRO

Q6NYC1

Pharos - Targets

Q6NYC1

GlyGen

Q6NYC1

PDB

6GDY, 3LD8, 6MEV, 3K2O, 6BNH, 3LDB

HMDB Protein

HMDBP02642

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O60885 BRD4	1	BRD4 [nucleoplasm] (R-HSA-9680425)	0.782	11
UniProt:Q9GZZ1 NAA50			0.718	6
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.649	8
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.639	7
UniProt:Q9NP64 ZCC17			0.632	6
UniProt:Q01081 U2AF1	1	U2AF1 [nucleoplasm] (R-HSA-71985)	0.632	4
UniProt:Q8NAV1 PRPF38A	1	PRPF38A [nucleoplasm] (R-HSA-8867897)	0.632	5
UniProt:Q9NWB6 ARGL1			0.564	4
UniProt:Q96NE9 FRMD6			0.556	3
UniProt:Q9UK58 CCNL1			0.547	3
UniProt:Q96IZ7 RSRC1			0.547	4
UniProt:Q8IZU1 FAM9A			0.547	2
UniProt:P50750 CDK9	1	CDK9 [nucleoplasm] (R-HSA-51801)	0.544	5
UniProt:Q16630 CPSF6	2	CPSF6(1-490)-FGFR1(429-822) fusion [cytosol] (R-HSA-1614368) CPSF6(1-490)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1838987)	0.527	3
UniProt:Q14498 RBM39	1	RBM39 [nucleoplasm] (R-HSA-9770254)	0.527	4
UniProt:P49761 CLK3			0.527	4
UniProt:Q9BU76 MMTAG2	3	MMTAG2 [ficolin-1-rich granule lumen] (R-HSA-6801074) MMTAG2 [extracellular region] (R-HSA-6806452) MMTAG2 [secretory granule lumen] (R-HSA-6801073)	0.527	3
UniProt:Q9UHX1 PUF60	1	PUF60 [nucleoplasm] (R-HSA-8865910)	0.527	4
UniProt:Q8N5F7 NKAP	1	NKAP [nucleoplasm] (R-HSA-9769602)	0.527	5
UniProt:Q86X55 CARM1	1	CARM1 [nucleoplasm] (R-HSA-400139)	0.499	2

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