YWHAB [cytosol]

Stable Identifier
R-HSA-48888
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
14-3-3 protein beta/alpha, 143B protein, Protein kinase C inhibitor protein-1, KCIP-1, Protein 1054
Icon
YWHAB [cytosol] icon
YWHAB [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P31946 YWHAB
Gene Names
YWHAB
Chain
chain:1-246, initiator methionine:, chain:2-246
Reference Genes
BioGPS Gene:7529 YWHAB
COSMIC (genes):YWHAB YWHAB
CTD Gene:7529 YWHAB
dbSNP Gene:7529 YWHAB
ENSEMBL:ENSG00000166913 YWHAB
ENSEMBL_homo_sapiens_GENE:ENSG00000166913.13 YWHAB
HGNC:12849 YWHAB
KEGG Gene (Homo sapiens):7529 YWHAB
Monarch:7529 YWHAB
NCBI Gene:7529 YWHAB
OMIM:601289 YWHAB
Reference Transcript
Other Identifiers
11725042_a_at
11725043_a_at
11725044_s_at
11731397_a_at
11757887_x_at
16914103
208743_PM_s_at
208743_s_at
217717_PM_s_at
217717_s_at
217718_PM_s_at
217718_s_at
32324_at
3886640
3886643
3886644
3886649
3886650
3886652
3886654
3886655
3886656
3886657
3886658
3886659
3886661
3886662
7529
8062880
A_23_P120414
GE81853
GO:0004860
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005773
GO:0005774
GO:0005829
GO:0005925
GO:0006605
GO:0006886
GO:0007165
GO:0016020
GO:0019899
GO:0019904
GO:0023052
GO:0031410
GO:0035308
GO:0036211
GO:0042470
GO:0042802
GO:0042826
GO:0043085
GO:0043226
GO:0045296
GO:0045744
GO:0048471
GO:0050815
GO:0051219
GO:0051220
GO:0070062
GO:0098772
HMNXSV003042369
Hs.182238.0.A1_3p_a_at
ILMN_1694385
ILMN_2277099
PH_hs_0023424
TC20000337.hg
X57346_at
g12655022_3p_s_at
g7661715_3p_a_at
Participates
as a component of
as an input of
as a member of
Inferred To
14-3-3zeta [cytosol] (Drosophila melanogaster)
par-5 [cytosol] (Caenorhabditis elegans)
ywhab [cytosol] (Xenopus tropicalis)
14-3-3I [cytosol] (Plasmodium falciparum)
Ghost homologue of YWHAB [cytosol] (Canis familiaris)
Ghost homologue of YWHAB [cytosol] (Dictyostelium discoideum)
Ywhab [cytosol] (Rattus norvegicus)
ywhabb [cytosol] (Danio rerio)
14-3-3 beta/alpha [cytosol] (Mus musculus)
YWHAB [cytosol] (Bos taurus)
YWHAB [cytosol] (Gallus gallus)
YWHAB [cytosol] (Sus scrofa)
Homologues of YWHAB [cytosol] (Caenorhabditis elegans)
ftt-2 [cytosol] (Caenorhabditis elegans)
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
HMDB Protein
PDB
Interactors (319)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P04049 RAF1  20 0.955 38
 UniProt:P49815 TSC2  4 0.945 15
 UniProt:P62258 YWHAE  1 0.919 15
 UniProt:P27448 MARK3  1 0.916 13
 UniProt:P15056 BRAF  20 0.905 11
 UniProt:P30305 CDC25B  3 0.894 8
 UniProt:P46937 YAP1  8 0.894 9
 UniProt:P61981 YWHAG  1 0.889 9
 UniProt:Q9Y2U5 M3K2      0.888 7
 UniProt:P30307 CDC25C  8 0.886 8
 UniProt:O96013 PAK4  1 0.88 9
 UniProt:P63104 YWHAZ  2 0.869 10
 UniProt:Q7Z401 DENND4A  1 0.867 10
 UniProt:Q86X27 RGPS2      0.867 8
 UniProt:Q8TEW0 PARD3  3 0.867 9
 UniProt:P40818 USP8  2 0.867 9
 UniProt:Q02241 KIF23  3 0.867 8
 UniProt:Q5TCX8 M3K21      0.859 8
 UniProt:P26045 PTPN3  3 0.859 8
 UniProt:Q6ICG6 K0930      0.857 7
 UniProt:Q12802 AKAP13  1 0.851 7
 UniProt:P27348 YWHAQ  1 0.851 8
 UniProt:Q7KZI7 MARK2      0.848 8
 UniProt:Q53ET0 CRTC2  1 0.848 7
 UniProt:P10398 ARAF  4 0.837 10
 UniProt:Q04917 YWHAH  1 0.837 7
 UniProt:P08069 IGF1R  3 0.832 7
 UniProt:Q07866 KLC1  3 0.826 6
 UniProt:Q6PKG0 LARP1  1 0.826 8
 UniProt:Q9Y4H2 IRS2  4 0.826 7
 UniProt:Q96TC7 RMD3      0.82 8
 UniProt:Q9NSK0 KLC4  1 0.816 7
 UniProt:Q86W92 PPFIBP1  5 0.816 7
 UniProt:Q96Q42 ALS2  1 0.813 5
 UniProt:Q14C86 GAPVD1  1 0.813 5
 UniProt:Q9UBF8 PI4KB  2 0.813 6
 UniProt:Q96F86 EDC3  1 0.806 7
 UniProt:Q9Y2J2 EPB41L3  1 0.806 5
 UniProt:O94915 FRYL      0.806 5
 UniProt:P33176 KIF5B  3 0.806 5
 UniProt:Q9Y6M7 SLC4A7  1 0.806 6
 UniProt:Q96NE9 FRMD6      0.806 5
 UniProt:Q6WCQ1 MPRIP  2 0.806 6
 UniProt:Q5PRF9 SMAG2      0.802 5
 UniProt:Q92934 BAD  4 0.798 6
 UniProt:P30291 WEE1  3 0.796 5
 UniProt:Q02750 MAP2K1  20 0.788 7
 UniProt:P22681 CBL  20 0.788 5
 UniProt:Q6R327 RICTOR  1 0.774 6
 UniProt:P56524 HDAC4  3 0.774 6
 UniProt:O43524 FOXO3  11 0.774 6
 UniProt:Q8N3F8 MILK1      0.758 4
 UniProt:Q9Y2A7 NCKAP1  1 0.758 5
 UniProt:Q9H4L5 OSBPL3  1 0.758 4
 UniProt:Q9P0K7 RAI14      0.758 4
 UniProt:Q9H0H5 RACGAP1  1 0.758 4
 UniProt:Q5S007 LRRK2  1 0.75 5
 UniProt:Q9UJ41 RABGEF1  2 0.749 4
 UniProt:O75592 MYCB2      0.749 5
 UniProt:Q86X29 LSR  1 0.749 5
 UniProt:Q92625 ANS1A      0.745 5
 UniProt:Q5TCZ1 SH3PXD2A  1 0.745 6
 UniProt:Q86SQ0 PHLB2      0.745 6
 UniProt:Q7Z460 CLASP1  1 0.745 7
 UniProt:Q9P2F8 SI1L2      0.745 6
 UniProt:O60333 KIF1B  1 0.745 6
 UniProt:O75122 CLASP2  1 0.745 8
 UniProt:Q5JSL3 DOCK11  1 0.745 6
 UniProt:Q8IVT5 KSR1  5 0.745 5
 UniProt:Q6IQ23 PKHA7      0.745 6
 UniProt:Q5VZ89 DENND4C  1 0.745 6
 UniProt:O14654 IRS4  2 0.745 6
 UniProt:O14639 ABLIM1  1 0.745 6
 UniProt:Q9H0B6 KLC2  1 0.745 6
 UniProt:Q86TI0 TBC1D1  2 0.745 6
 UniProt:O00443 PIK3C2A  3 0.745 6
 UniProt:Q99759 MAP3K3  1 0.744 5
 UniProt:P54253 ATX1      0.737 5
 UniProt:Q9P0V3 SH3BP4  1 0.731 5
 UniProt:Q92538 GBF1  2 0.731 4
 UniProt:Q9UQC2 GAB2  5 0.727 7
 UniProt:Q07002 CDK18      0.725 4
 UniProt:Q15032 R3HD1      0.725 4
 UniProt:O60825 PFKFB2  1 0.725 5
 UniProt:P36507 MAP2K2  12 0.725 6
 UniProt:Q9UQL6 HDAC5  1 0.725 4
 UniProt:Q00537 CDK17      0.725 4
 UniProt:P22893  2 0.725 5
 UniProt:Q96B36 AKT1S1  4 0.725 4
 UniProt:P00519 ABL1  6 0.725 4
 UniProt:Q99683 MAP3K5  1 0.716 4
 UniProt:O60343 TBC1D4  2 0.706 5
 UniProt:O95544 NADK  1 0.706 4
 UniProt:Q9H6H4 REEP4      0.706 5
 UniProt:Q8WWI1 LMO7  3 0.706 4
 UniProt:Q9UJF2 RASAL2  1 0.706 5
 UniProt:Q9H4A3 WNK1  1 0.706 5
 UniProt:Q6UUV7 CRTC3  1 0.706 5
 UniProt:Q9Y3R0 GRIP1  2 0.706 4
 UniProt:O43379 WDR62      0.706 5
 UniProt:Q8TF72 SHRM3      0.706 4
 UniProt:Q8NEY1 NAV1      0.706 5
 UniProt:Q6P0Q8 MAST2      0.706 4
 UniProt:Q7L804 RAB11FIP2  1 0.706 5
 UniProt:Q9UQB8 BAIAP2  1 0.706 6
 UniProt:O75044 SRGAP2  1 0.706 4
 UniProt:P30304 CDC25A  6 0.701 10
 UniProt:P55196 AFDN      0.695 5
 UniProt:Q16890 TPD52L1  2 0.691 4
 UniProt:Q96JH8 RADIL      0.688 3
 UniProt:P68400 CSNK2A1  2 0.688 3
 UniProt:O94921 CDK14      0.681 6
 UniProt:P19634 SLC9A1  1 0.678 4
 UniProt:Q9UQ35 SRRM2  1 0.674 3
 UniProt:Q15678 PTPN14  1 0.671 5
 UniProt:Q9Y6R0 NUMBL      0.671 4
 UniProt:Q8N8E3 CE112      0.671 4
 UniProt:Q9NYL2 M3K20      0.671 4
 UniProt:Q6WKZ4 RFIP1      0.671 5
 UniProt:Q9ULJ3 ZBT21      0.671 4
 UniProt:Q6UUV9 CRTC1  1 0.671 4
 UniProt:Q16204 CCDC6      0.671 4
 UniProt:Q92974 ARHGEF2  1 0.671 5
 UniProt:Q13625 TP53BP2  1 0.671 4
 UniProt:O15049 N4BP3      0.671 5
 UniProt:P21359 NF1  20 0.671 4
 UniProt:Q14671 PUM1  1 0.671 5
 UniProt:O14649 KCNK3  1 0.67 5
 UniProt:Q92574 TSC1  2 0.669 3
 UniProt:Q13627 DYRK1A  1 0.669 3
 UniProt:P31946 YWHAB  1 0.667 3
 UniProt:P42858 HTT  1 0.666 11
 UniProt:Q9P2M7 CGN  1 0.65 4
 UniProt:Q9NYF3 FA53C      0.643 3
 UniProt:Q9BPZ7 MAPKAP1  1 0.643 3
 UniProt:O43896 KIF1C  1 0.643 3
 UniProt:Q9Y2K5 R3HD2      0.643 3
 UniProt:Q8WUI4 HDAC7  1 0.643 4
 UniProt:Q6NUK4 REEP3      0.643 4
 UniProt:Q9P0L2 MARK1      0.643 3
 UniProt:Q9ULR3 PPM1H      0.643 3
 UniProt:Q00536 CDK16      0.643 3
 UniProt:Q96GV9 MACIR      0.643 3
 UniProt:Q70EL4 USP43  1 0.643 3
 UniProt:Q9NQC7 CYLD  3 0.643 3
 UniProt:Q8WX92 NELFB  3 0.643 3
 UniProt:Q12778 FOXO1  5 0.643 3
 UniProt:Q51451 Q51451      0.637 3
 UniProt:Q61097  5 0.632 3
 UniProt:Q99959 PKP2  2 0.615 4
 UniProt:Q13136 PPFIA1  1 0.615 3
 UniProt:P85037 FOXK1  1 0.615 3
 UniProt:Q86V48 LUZP1      0.615 4
 UniProt:Q9UPN4 CEP131  1 0.615 4
 UniProt:Q4KWH8 PLCH1  1 0.615 4
 UniProt:Q3V6T2 CCDC88A  1 0.615 4
 UniProt:Q5T0W9 FAM83B  1 0.615 4
 UniProt:Q96S53 TESK2      0.615 3
 UniProt:A0JNW5 BLTP3B  1 0.615 3
 UniProt:Q9UPU9 SMAG1      0.615 3
 UniProt:A7KAX9 ARHGAP32  1 0.615 4
 UniProt:Q5VT97 SYDE2  1 0.615 3
 UniProt:Q6AWC2 WWC2      0.615 3
 UniProt:Q9Y4F5 C170B      0.615 4
 UniProt:Q15276 RABEP1  1 0.615 3
 UniProt:Q9UQ84 EXO1  1 0.615 3
 UniProt:O15063 GARRE1  1 0.615 4
 UniProt:Q96PY6 NEK1  1 0.615 4
 UniProt:O60292 SI1L3      0.615 5
 UniProt:Q8IUD2 RB6I2      0.615 3